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Deiodinase-3 is a thyrostat to regulate podocyte homeostasis

Authors: Shivangi Agarwal, Kwi Hye Koh, Nicholas J Tardi, Chuang Chen, Ranadheer Reddy Dande, Joao Pedro WerneckdeCastro, Yashwanth Reddy Sudhini, Cristina Luongo, Domenico Salvatore, Beata Samelko, Mehmet M Altintas, Steve Mangos, Antonio Bianco, Jochen Reiser

Journal: EBioMedicine

PubMed ID: 34649077

Doi: 10.1016/j.ebiom.2021.103617

Products & Services: Plasmid DNA Preparation

Brain cross-protection against SARS-CoV-2 variants by a lentiviral vaccine in new transgenic mice

Authors: Min-Wen Ku, Pierre Authié, Maryline Bourgine, François Anna, Amandine Noirat, Fanny Moncoq, Benjamin Vesin, Fabien Nevo, Jodie Lopez, Philippe Souque, Catherine Blanc, Ingrid Fert, Sébastien Chardenoux, Llta Lafosse, Delphine Cussigh, David Hardy, Kirill Nemirov, Françoise Guinet, Francina Langa Vives, Laleh Majlessi, Pierre Charneau

Journal: EMBO Mol Med

PubMed ID: 34647691

Doi: 10.15252/emmm.202114459

Products & Services: Molecular Biology Reagents

The GPR171 pathway suppresses T cell activation and limits antitumor immunity

Authors: Yuki Fujiwara, Robert J Torphy, Yi Sun, Emily N Miller, Felix Ho, Nicholas Borcherding, Tuoqi Wu, Raul M Torres, Weizhou Zhang, Richard D Schulick, Yuwen Zhu

Journal: Nat Commun

PubMed ID: 34615877

Doi: 10.1038/s41467-021-26135-9

Products & Services: Peptide Synthesis

Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance

Authors: Xuezhi Cao, Yong Liang, Zhenxiang Hu, Huiyu Li, Jiaming Yang, Eric J Hsu, Jiankun Zhu, Jin Zhou, Yang-Xin Fu

Journal: Nat Commun

PubMed ID: 34620867

Doi: 10.1038/s41467-021-26112-2

Products & Services: Endotoxin Detection & Removal System

Structural determinants of the integrin transmembrane domain required for bidirectional signal transmission across the cell membrane

Authors: Zhengli Wang, Jieqing Zhu

Journal: J Biol Chem

PubMed ID: 34678312

Doi: 10.1016/j.jbc.2021.101318

Products & Services: Protein and Antibody Isolation

Complete three-dimensional structures of the Lon protease translocating a protein substrate

Authors: Shanshan Li, Kan-Yen Hsieh, Chiao-I Kuo, Szu-Hui Lee, Grigore D Pintilie, Kaiming Zhang, Chung-I Chang

Journal: Sci Adv

PubMed ID: 34652947

Doi: 10.1126/sciadv.abj7835

Products & Services: Protein Electrophoresis and Western

Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes

Authors: Yingjuan J Lu, Leroy W Wheeler, Haiyan Chu, Paul J Kleindl, Michael Pugh, Fei You, Satish Rao, Gabriela Garcia, Henry Y Wu, Andre P da Cunha, Richard Johnson, Elaine Westrick, Vicky Cross, Alex Lloyd, Christina Dircksen, Patrick J Klein, Iontcho R Vlahov, Philip S Low, Christopher P Leamon

Journal: Cell Rep Med

PubMed ID: 34755134

Doi: 10.1016/j.xcrm.2021.100422

Products & Services: Mammalian Expression

PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis

Authors: Sophie Sluysmans, Isabelle Méan, Tong Xiao, Amina Boukhatemi, Flavio Ferreira, Lionel Jond, Annick Mutero, Christopher J Chang, Sandra Citi

Journal: Mol Biol Cell

PubMed ID: 34613798

Doi: 10.1091/mbc.E21-07-0355

Products & Services: Molecular Biology Tools

Modulating immune responses to AAV by expanded polyclonal T-regs and capsid specific chimeric antigen receptor T-regulatory cells

Authors: Motahareh Arjomandnejad, Katelyn Sylvia, Meghan Blackwood, Thomas Nixon, Qiushi Tang, Manish Muhuri, Alisha M Gruntman, Guangping Gao, Terence R Flotte, Allison M Keeler

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34853797

Doi: 10.1016/j.omtm.2021.10.010

Products & Services: Peptide Synthesis

Two Novel Hydroxymethylbilane Synthase Splicing Mutations Predispose to Acute Intermittent Porphyria

Authors: Yanping Zhang, Han Xiao, Qiuhong Xiong, Changxin Wu, Ping Li

Journal: Int J Mol Sci

PubMed ID: 34681668

Doi: 10.3390/ijms222011008

Products & Services: Custom Vector Construction