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Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression

Authors: Gloria Gamiz-Arco, Valeria A Risso, Eric A Gaucher, Jose A Gavira, Athi N Naganathan, Beatriz Ibarra-Molero, Jose M Sanchez-Ruiz

Journal: J Mol Biol

PubMed ID: 34687715

Doi: 10.1016/j.jmb.2021.167321

Products & Services: Plasmid DNA Preparation

Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring

Authors: Fengzhen Cui, Qingfei Pan, Siyi Wang, Faming Zhao, Runxin Wang, Tingting Zhang, Yaying Song, Jun He, Haolin Zhang, Qiang Weng, Yang Jin, Wei Xia, Yuanyuan Li, Guo-Yuan Yang, Winnok H De Vos, Jean-Pierre Timmermans, Shunqing Xu, Yaohui Tang, Xia Sheng

Journal: Adv Sci (Weinh)

PubMed ID: 34713618

Doi: 10.1002/advs.202102686

Products & Services: Gene Synthesis

Non-canonical activation of the ER stress sensor ATF6 by effectors

Authors: Nnejiuwa U Ibe, Advait Subramanian, Shaeri Mukherjee

Journal: Life Sci Alliance

PubMed ID: 34635501

Doi: 10.26508/lsa.202101247

Products & Services: Mutant Libraries

Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling

Authors: Jiajia Wang, Jiaying Wang, Wenxiang Hong, Lulu Zhang, Liqian Song, Qi Shi, Yanfei Shao, Guifeng Hao, Chunyan Fang, Yueping Qiu, Lijun Yang, Zhaoxu Yang, Jincheng Wang, Ji Cao, Bo Yang, Qiaojun He, Qinjie Weng

Journal: Nat Commun

PubMed ID: 34707127

Doi: 10.1038/s41467-021-26477-4

Products & Services: Plasmid DNA Preparation

Mdivi-1 Modulates Macrophage/Microglial Polarization in Mice with EAE via the Inhibition of the TLR2/4-GSK3β-NF-κB Inflammatory Signaling Axis

Authors: Xiaoqin Liu, Xiaojuan Zhang, Xiaojie Niu, Peijun Zhang, Qing Wang, Xiuhua Xue, Guobin Song, Jiezhong Yu, Guoping Xi, Lijuan Song, Yanhua Li, Cungen Ma

Journal: Mol Neurobiol

PubMed ID: 34618332

Doi: 10.1007/s12035-021-02552-1

Products & Services: Custom DNA/RNA Oligos

Development of recombinant COVID-19 vaccine based on CHO-produced, prefusion spike trimer and alum/CpG adjuvants

Authors: Haitao Liu, Chenliang Zhou, Jiao An, Yujiao Song, Pin Yu, Jiadai Li, Chenjian Gu, Dongdong Hu, Yuanxiang Jiang, Lingli Zhang, Chuanqi Huang, Chao Zhang, Yunqi Yang, Qianjun Zhu, Dekui Wang, Yuqiang Liu, Chenyang Miao, Xiayao Cao, Longfei Ding, Yuanfei Zhu, Hua Zhu, Linlin Bao, Lingyun Zhou, Huan Yan, Jiang Fan, Jianqing Xu, Zhongyu Hu, Youhua Xie, Jiangning Liu, Ge Liu

Journal: Vaccine

PubMed ID: 34750014

Doi: 10.1016/j.vaccine.2021.10.066

Products & Services: Peptide Synthesis

SDCBP Modulates Stemness and Chemoresistance in Head and Neck Squamous Cell Carcinoma through Src Activation

Authors: Cristina Mir, Yoelsis Garcia-Mayea, Laia Garcia, Pol Herrero, Nuria Canela, Rocío Tabernero, Juan Lorente, Josep Castellvi, Eva Allonca, Juana García-Pedrero, Juan Pablo Rodrigo, Ángel Carracedo, Matilde Esther LLeonart

Journal: Cancers (Basel)

PubMed ID: 34638436

Doi: 10.3390/cancers13194952

Products & Services: ORF cDNA Clones/MolecularCloud

Epigenetic Silencing of BMP6 by the SIN3A-HDAC1/2 Repressor Complex Drives Melanoma Metastasis via FAM83G/PAWS1

Authors: Dongkook Min, Jaemin Byun, Eun-Joon Lee, Abdul A Khan, Christina Liu, Oliver Loudig, Wei Hu, Yong Zhao, Meenhard Herlyn, Benjamin Tycko, Phillip A Cole, Byungwoo Ryu

Journal: Mol Cancer Res

PubMed ID: 34610961

Doi: 10.1158/1541-7786.MCR-21-0289

Products & Services: ORF cDNA Clones/MolecularCloud

The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type α-synuclein

Authors: Yunpeng Sun, Houfang Long, Wencheng Xia, Kun Wang, Xia Zhang, Bo Sun, Qin Cao, Yaoyang Zhang, Bin Dai, Dan Li, Cong Liu

Journal: Nat Commun

PubMed ID: 34716315

Doi: 10.1038/s41467-021-26433-2

Products & Services: Protein and Antibody Isolation

Immune Responses to Orally Administered Recombinant Expressing Multi-Epitope Proteins Targeting M Cells of Foot-and-Mouth Disease Virus

Authors: Fudong Zhang, Zhongwang Zhang, Xian Li, Jiahao Li, Jianliang Lv, Zhongyuan Ma, Li Pan