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Blood virosphere in febrile Tanzanian children

Authors: Samuel Cordey, Florian Laubscher, Mary-Anne Hartley, Thomas Junier, Kristina Keitel, Mylène Docquier, Nicolas Guex, Christian Iseli, Gael Vieille, Philippe Le Mercier, Anne Gleizes, Josephine Samaka, Tarsis Mlaganile, Frank Kagoro, John Masimba, Zamzam Said, Hosiana Temba, Gasser H Elbanna, Caroline Tapparel, Marie-Celine Zanella, Ioannis Xenarios, Jacques Fellay, Valérie D'Acremont, Laurent Kaiser

Journal: Emerg Microbes Infect

PubMed ID: 33929935

Doi: 10.1080/22221751.2021.1925161

Products & Services: Gene Synthesis

Long-term trajectories of SARS-CoV-2 neutralizing antibodies and predictive value of first dose vaccination-induced IgG-antibodies in hemodialysis patients

Authors: F P Tillmann, H Still, Philipp von Landenberg

Journal: Int Urol Nephrol

PubMed ID: 34860338

Doi: 10.1007/s11255-021-03076-2

Products & Services: Protein and Antibody Reagents

Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA

Authors: Kun Huang, Xiao-Xian Wu, Cheng-Li Fang, Zhou-Geng Xu, Hong-Wei Zhang, Jian Gao, Chuan-Miao Zhou, Lin-Lin You, Zhan-Xi Gu, Wen-Hui Mu, Yu Feng, Jia-Wei Wang, Yu Zhang

Journal: Science

PubMed ID: 34941388

Products & Services: Gene Synthesis

Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands

Authors: Edmond M Linossi , Kunlun Li , Gianluca Veggiani , Cyrus Tan , Farhad Dehkhoda , Colin Hockings , Dale J Calleja , Narelle Keating , Rebecca Feltham , Andrew J Brooks , Shawn S Li , Sachdev S Sidhu , Jeffrey J Babon , Nadia J Kershaw , Sandra E Nicholson

Journal: Nat Commun

PubMed ID: 34857742

Doi: s41467-021-26983-5

Products & Services: Peptide Synthesis

Local Charge Distributions, Electric Dipole Moments, and Local Electric Fields Influence Reactivity Patterns and Guide Regioselectivities in α-Ketoglutarate-Dependent Non-heme Iron Dioxygenases

Authors: Sam P de Visser, Gourab Mukherjee, Hafiz Saqib Ali, Chivukula V Sastri

Journal: Acc Chem Res

PubMed ID: 34915695

Doi: 10.1021/acs.accounts.1c00538

Products & Services: Custom Vector Construction

Chlorogenic Acid-Induced Gut Microbiota Improves Metabolic Endotoxemia

Authors: Xiaolin Ye, Yang Liu, Jiajin Hu, Yanyan Gao, Yanan Ma, Deliang Wen

Journal: Front Endocrinol (Lausanne)

PubMed ID: 34975748

Doi: 10.3389/fendo.2021.762691

Products & Services: Endotoxin Detection & Removal System

A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors

Authors: K Y Chen, T Krischuns, L Ortega Varga, E Harigua-Souiai, S Paisant, A Zettor, J Chiaravalli, D Courtney, A O'Brien, S C Baker, C Isel, F Agou, Y Jacob, A Blondel, N Naffakh

Journal: biorxiv

PubMed ID: 34981051

Doi: 10.1101/2021.12.18.473303

Products & Services: PCR Cloning and Subcloning

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

Authors: Sandile Cele, Laurelle Jackson, David S Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally, James Emmanuel San, Deborah Cromer, Cathrine Scheepers, Daniel G Amoako, Farina Karim, Mallory Bernstein, Gila Lustig, Derseree Archary, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Shi-Hsia Hwa, Jennifer Giandhari, Jonathan M Blackburn, Bernadett I Gosnell, Salim S Abdool Karim, Willem Hanekom, Anne von Gottberg, Jinal N Bhiman, Richard J Lessells, Mahomed-Yunus S Moosa, Miles P Davenport, Tulio de Oliveira, Penny L Moore, Alex Sigal

Journal: Nature

PubMed ID: 35016196

Doi: 10.1038/s41586-021-04387-1

Products & Services: Monoclonal Antibody Services

Cepharanthine Blocks Presentation of Thyroid and Islet Peptides in a Novel Humanized Autoimmune Diabetes and Thyroiditis Mouse Model

Authors: Cheuk Wun Li, Roman Osman, Francesca Menconi, Larissa C Faustino, Kookjoo Kim, Oliver B Clarke, Hanxi Hou, Yaron Tomer

Journal: Front Immunol

PubMed ID: 34987519

Doi: 10.3389/fimmu.2021.796552

Products & Services: Peptide Synthesis

Novel Tyrosine Kinase-Mediated Phosphorylation With Dual Specificity Plays a Key Role in the Modulation of Physiology and Virulence

Authors: Sashi Kant, Vijay Pancholi