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The insecticide β-Cyfluthrin induces acute arrhythmic cardiotoxicity through interaction with NaV15 and ranolazine reverses the phenotype

Authors: Maria Vitoria da Silva, Artur Santos-Miranda, Julliane V Joviano-Santos, Diego Santos Souza, Leisiane Pereira Marques, Jaqueline Oliveira Sarmento, Samuel Santos Beserra, Danilo Roman-Campos

Journal: Clin Sci (Lond)

PubMed ID: 35190819

Doi: 10.1042/CS20211151

Products & Services: Mammalian Expression

Structural and functional characterizations of infectivity and immune evasion of SARS-COV-2Omicron

Authors: Zhen Cui, Pan Liu, Nan Wang, Lei Wang, Kaiyue Fan, Qianhui Zhu, Kang Wang, Ruihong Chen, Rui Feng, Zijing Jia, Minnan Yang, Ge Xu, Boling Zhu, Wangjun Fu, Tianming Chu, Leilei Feng, Yide Wang, Xinran Pei, Peng Yang, Xiaoliang Sunney Xie, Lei Cao, Yunlong Cao, Xiangxi Wang

Journal: Cell

PubMed ID: 35120603

Doi: 10.1016/j.cell.2022.01.019

Products & Services: Custom Vector Construction

Machine learning discovery of missing links that mediate alternative branches to plant alkaloids

Authors: Christopher J. Vavricka; Shunsuke Takahashi; Naoki Watanabe; Musashi Takenaka; Mami Matsuda; Takanobu Yoshida; Ryo Suzuki; Hiromasa Kiyota; Jianyong Li; Hiromichi Minami; Jun Ishii; Kenji Tsuge; Michihiro Araki; Akihiko Kondo; Tomohisa Hasunuma

Journal: Nature Communications

PubMed ID: 35296652

Doi: 10.1038/s41467-022-28883-8

A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus

Authors: Peter J. Hoferle; Thomas K. Anderson; Robert N. Kirchdoerfer

Journal: The Journal of Biological Chemistry

PubMed ID: 39307300

Doi: 10.1016/j.jbc.2024.107802

A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus

Authors: Peter J. Hoferle; Thomas K. Anderson; Robert N. Kirchdoerfer

Journal: The Journal of Biological Chemistry

PubMed ID: 39307300

Doi: 10.1016/j.jbc.2024.107802

SERTAD3 induces proteasomal degradation of ZIKV capsid protein and represents a therapeutic target

Authors: Nina Sun; Rong-Rong Zhang; Guang-Yuan Song; Qiaomei Cai; Saba R. Aliyari; Karin Nielsen-Saines; Jae U. Jung; Heng Yang; Genhong Cheng; Cheng-Feng Qin

Journal: Journal of medical virology

PubMed ID: 36594413

Doi: 10.1002/jmv.28451

Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

Authors: Oskar Staufer, Kapil Gupta, Jochen Estebano Hernandez Bücher, Fabian Kohler, Christian Sigl, Gunjita Singh, Kate Vasileiou, Ana Yagüe Relimpio, Meline Macher, Sebastian Fabritz, Hendrik Dietz, Elisabetta Ada Cavalcanti Adam, Christiane Schaffitzel, Alessia Ruggieri, Ilia Platzman, Imre Berger, Joachim P Spatz

Journal: Nat Commun

PubMed ID: 35165285

Doi: 10.1038/s41467-022-28446-x

Products & Services: Plasmid DNA Preparation

A Lateral Flow Immunoassay Coupled with a Spectrum-Based Reader for SARS-CoV-2 Neutralizing Antibody Detection

Authors: Rui-Lin Huang, Yi-Chen Fu, Yung-Chih Wang, Chitsung Hong, Wei-Chieh Yang, I-Jen Wang, Jun-Ren Sun, Yunching Chen, Ching-Fen Shen, Chao-Min Cheng

Journal: Vaccines (Basel)

PubMed ID: 35214731

Doi: 10.3390/vaccines10020271

Products & Services: Molecular Biology Reagents

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2

Authors: Youwen Zhuang, Lei Wang, Jia Guo, Dapeng Sun, Yue Wang, Weiyi Liu, H Eric Xu, Cheng Zhang

Journal: Nat Commun

PubMed ID: 35217703

Doi: 10.1038/s41467-022-28586-0

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N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum

Authors: Samuel Pazicky, Arne Alder, Haydyn Mertens, Dmitri Svergun, Tim Gilberger, Christian Löw

Journal: Biochem J

PubMed ID: 35023554

Doi: 10.1042/BCJ20210829

Products & Services: Mutant Libraries