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Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging

Authors: Manning Y Huang, Meenakshi B Joshi, Michael J Boucher, Sujin Lee, Liza C Loza, Elizabeth A Gaylord, Tamara L Doering, Hiten D Madhani

Journal: Genetics

PubMed ID: 34791226

Doi: 10.1093/genetics/iyab180

Products & Services: Gene Synthesis

Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

Authors: Eva Pauwels, Becky Provinciael, Anita Camps, Enno Hartmann, Kurt Vermeire

Journal: Int J Mol Sci

PubMed ID: 35054769

Doi: 10.3390/ijms23020584

Products & Services: Protein and Antibody Isolation

Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

Authors: Yaw Bia Tan, Laura Sandra Lello, Xin Liu, Yee-Song Law, Congbao Kang, Julien Lescar, Jie Zheng, Andres Merits, Dahai Luo

Journal: Nucleic Acids Res

PubMed ID: 35037043

Doi: 10.1093/nar/gkab1302

Products & Services: Gene Fragments Gene Synthesis

Immunogenicity of a recombinant VSV-Vectored SARS-CoV vaccine induced robust immunity in rhesus monkeys after single-dose immunization

Authors: Dan Shan, Xiaoyan Tang, Renqiang Liu, Dan Pan, Xijun Wang, Jinying Ge, Zhiyuan Wen, Zhigao Bu

Journal: Virol Sin

PubMed ID: 35234625

Doi: 10.1016/j.virs.2022.01.002

Products & Services: Catalog Antibodies

Dimensionless parameter predicts bacterial prodrug success

Authors: Brandon Alexander Holt, McKenzie Tuttle, Yilin Xu, Melanie Su, Joachim J Røise, Xioajian Wang, Niren Murthy, Gabriel A Kwong

Journal: Mol Syst Biol

PubMed ID: 35005851

Doi: 10.15252/msb.202110495

Products & Services: Catalog Peptides

Investigating Constraints Along the Plant Secretory Pathway to Improve Production of a SARS-CoV-2 Spike Vaccine Candidate

Authors: Emmanuel Margolin, Matthew Verbeek, Warren de Moor, Ros Chapman, Ann Meyers, Georgia Schäfer, Anna-Lise Williamson, Edward Rybicki

Journal: Front Plant Sci

PubMed ID: 35058959

Doi: 10.3389/fpls.2021.798822

Products & Services: Mammalian Expression

Myricetin Allosterically Inhibits the Dengue NS2B-NS3 Protease by Disrupting the Active and Locking the Inactive Conformations

Authors: Mei Dang, Liangzhong Lim, Amrita Roy, Jianxing Song

Journal: ACS Omega

PubMed ID: 35097276

Doi: 10.1021/acsomega.1c05569

Products & Services: Recombinant Proteins

ROS-regulated phosphorylation of ITPKB by CAMK2G drives cisplatin resistance in ovarian cancer

Authors: Jie Li, Cuimiao Zheng, Mingshuo Wang, Anna D Umano, Qingyuan Dai, Chunyu Zhang, Hua Huang, Qing Yang, Xianzhi Yang, Jingyi Lu, Wenfeng Pan, Bo Li, Shuzhong Yao, Chaoyun Pan

Journal: Oncogene

PubMed ID: 35039634

Doi: 10.1038/s41388-021-02149-x

Products & Services: Peptide Synthesis

Heterologous Expression and Functional Characterization of CAP18 from

Authors: Mahla Nikpoor, Azadeh Lohrasbi-Nejad, Jafar Zolala

Journal: Rep Biochem Mol Biol

PubMed ID: 35291606

Doi: 10.52547/rbmb.10.4.622

Products & Services: Protein and Antibody Isolation

A combination of multiple autoantibodies is associated with the risk of Alzheimer's disease and cognitive impairment

Authors: Sung-Mi Shim, Young Ho Koh, Jong-Hoon Kim, Jae-Pil Jeon

Journal: Sci Rep

PubMed ID: 35079008

Doi: 10.1038/s41598-021-04556-2

Products & Services: Catalog Antibodies