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RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants

Authors: Qingtai Liang, Yifeng Wang, Shuyuan Zhang, Jing Sun, Wenbo Sun, Jizhou Li, Yaping Liu, Mingxi Li, Lin Cheng, Yuhang Jiang, Ruoke Wang, Rui Zhang, Zihan Yang, Yifei Ren, Peng Chen, Peng Gao, Huayuan Yan, Zheng Zhang, Qi Zhang, Xuanling Shi, Jianbin Wang, Wanli Liu, Xinquan Wang, Bo Ying, Jincun Zhao, Hai Qi, Linqi Zhang

Journal: iScience

PubMed ID: 35291264

Doi: 10.1016/j.isci.2022.104043

Products & Services: Catalog Peptides

KIR3DL05 and KIR3DS02 Recognition of a Nonclassical MHC Class I Molecule in the Rhesus Macaque Implicated in Pregnancy Success

Authors: Rachel E Nicholas, Kjell Sandstrom, Jennifer L Anderson, Willow R Smith, Molly Wetzel, Priyankana Banerjee, Sanath Kumar Janaka, David T Evans

Journal: Front Immunol

PubMed ID: 35401580

Doi: 10.3389/fimmu.2022.841136

Products & Services: Custom Vector Construction

AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition

Authors: Yongchao Xie, Laixing Zhang, Zhengyu Gao, Peipei Yin, Hao Wang, Hang Li, Zeliang Chen, Yi Zhang, Maojun Yang, Yue Feng

Journal: Nat Chem Biol

PubMed ID: 35301482

Doi: 10.1038/s41589-022-00995-8

Products & Services: Molecular Biology Reagents

A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis

Authors: Yun Ji Park, Richard J Jodts, Jeffrey W Slater, Reyvin M Reyes, Valerie J Winton, Rana A Montaser, Paul M Thomas, William B Dowdle, Anahi Ruiz, Neil L Kelleher, J Martin Bollinger, Carsten Krebs, Brian M Hoffman, Amy C Rosenzweig

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35320042

Doi: 10.1073/pnas.2123566119

Products & Services: Custom Vector Construction

ARL6IP5 reduces cisplatin-resistance by suppressing DNA repair and promoting apoptosis pathways in ovarian carcinoma

Authors: Ji-Ye Kim, Entaz Bahar, Jung-Yun Lee, Sunhee Chang, Se Hoon Kim, Eun Young Park, Sung-Im Do, Hyonok Yoon, Hyun-Soo Kim

Journal: Cell Death Dis

PubMed ID: 35293383

Doi: 10.1038/s41419-022-04568-4

Products & Services: Plasmid DNA Preparation

Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells

Authors: Hang Yang, Huijun Yuan, Xiaohui Zhao, Meng Xun, Shangrui Guo, Nan Wang, Bing Liu, Hongliang Wang

Journal: Virol Sin

PubMed ID: 35272059

Doi: 10.1016/j.virs.2022.03.003

Products & Services: DNA Sequencing

Machine learning discovery of missing links that mediate alternative branches to plant alkaloids

Authors: Christopher J. Vavricka; Shunsuke Takahashi; Naoki Watanabe; Musashi Takenaka; Mami Matsuda; Takanobu Yoshida; Ryo Suzuki; Hiromasa Kiyota; Jianyong Li; Hiromichi Minami; Jun Ishii; Kenji Tsuge; Michihiro Araki; Akihiko Kondo; Tomohisa Hasunuma

Journal: Nature Communications

PubMed ID: 35296652

Doi: 10.1038/s41467-022-28883-8

A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus

Authors: Peter J. Hoferle; Thomas K. Anderson; Robert N. Kirchdoerfer

Journal: The Journal of Biological Chemistry

PubMed ID: 39307300

Doi: 10.1016/j.jbc.2024.107802

A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus

Authors: Peter J. Hoferle; Thomas K. Anderson; Robert N. Kirchdoerfer

Journal: The Journal of Biological Chemistry

PubMed ID: 39307300