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Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

Authors: Wei Shi, Lingshu Wang, Tongqing Zhou, Mallika Sastry, Eun Sung Yang, Yi Zhang, Man Chen, Xuejun Chen, Misook Choe, Adrian Creanga, Kwan Leung, Adam S Olia, Amarendra Pegu, Reda Rawi, Chen-Hsiang Shen, Erik-Stephane D Stancofski, Chloe Adrienna Talana, I-Ting Teng, Shuishu Wang, Kizzmekia S Corbett, Yaroslav Tsybovsky, John R Mascola, Peter D Kwong

Journal: biorxiv

PubMed ID: 35118472

Doi: 10.1101/2022.01.25.477770

Products & Services: Protein and Antibody Isolation

Three Specific Potential Epitopes That Could Be Recognized by T Cells of Convalescent COVID-19 Patients Were Identified From Spike Protein

Authors: Yunwen Zhang, Zhengrong Yang, Mingyuan Tang, Hao Li, Tian Tang, Guilian Li, Yifan Zhong, Xiaomin Zhang, Xiaohui Wang, Chuan Wang

Journal: Front Immunol

PubMed ID: 35154095

Doi: 10.3389/fimmu.2022.752622

Products & Services: Peptide Synthesis

Single-conformation spectroscopy of cold, protonated PG-containing peptides: switching β-turn types and formation of a sequential type II/II' double β-turn

Authors: John T Lawler, Christopher P Harrilal, Andrew F DeBlase, Edwin L Sibert, Scott A McLuckey, Timothy S Zwier

Journal: Phys Chem Chem Phys

PubMed ID: 35019911

Doi: 10.1039/d1cp04852j

Products & Services: Protein and Antibody Isolation

A murine Skint6 W168X allele contributes to autoimmune disease in a transgenic model

Authors: Jiyu Ju, Hui Wang, Meng Lian, Yatao Bao, Yanyan Zhang, Zhiwei Xu

Journal: Lupus

PubMed ID: 35045734

Doi: 10.1177/09612033221074544

Products & Services: Catalog Peptides

Comprehensive engineering of a therapeutic neutralizing antibody targeting SARS-CoV-2 spike protein to neutralize escape variants

Authors: Taichi Kuramochi, Siok Wan Gan, Adrian W S Ho, Bei Wang, Nagisa Kageji, Takeru Nambu, Sayaka Iida, Momoko Okuda-Miura, Wei Shan Chia, Chiew Ying Yeo, Dan Chen, Wen-Hsin Lee, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Cheng-I Wang, Tomoyuki Igawa, Hideaki Shimada

Journal: MAbs

PubMed ID: 35293276

Doi: 10.1080/19420862.2022.2040350

Products & Services: PCR Cloning and Subcloning

USF1 Transcriptionally Regulates UGT1A3 and Promotes Lung Adenocarcinoma Progression by Regulating Neurotrophin Signaling Pathway

Authors: Yu Wang, Yun-Xia Zhao, Xiang-Wei Zhang, Yuan-Zhu Jiang, Wei Ma, Lin Zhang, Wei Dong

Journal: Front Mol Biosci

PubMed ID: 35155573

Doi: 10.3389/fmolb.2022.758968

Products & Services: Peptide Synthesis

Ion currents through Kir potassium channels are gated by anionic lipids

Authors: Ruitao Jin, Sitong He, Katrina A Black, Oliver B Clarke, Di Wu, Jani R Bolla, Paul Johnson, Agalya Periasamy, Ahmad Wardak, Peter Czabotar, Peter M Colman, Carol V Robinson, Derek Laver, Brian J Smith, Jacqueline M Gulbis

Journal: Nat Commun

PubMed ID: 35079013

Doi: 10.1038/s41467-022-28148-4

Products & Services: Mutant Libraries

Covalent coupling of Spike's receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2

Authors:

Journal: Sci Rep

PubMed ID: 35027583

Doi: 10.1038/s41598-021-03675-0

Products & Services: Catalog Peptides

Rapid sequence evolution is associated with genetic incompatibilities in the plastid Clp complex

Authors: Salah E Abdel-Ghany, Lisa M LaManna, Haleakala T Harroun, Pal Maliga, Daniel B Sloan

Journal: Plant Mol Biol

PubMed ID: 35039977

Doi: 10.1007/s11103-022-01241-4

Products & Services: PCR Cloning and Subcloning

DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3

Authors: Feng Hu, Ki On Fong, May Pui Lai Cheung, Jessica Aijia Liu, Rui Liang, Tsz Wai Li, Rakesh Sharma, Philip Pun-Ching Ip, Xintao Yang, Martin Cheung

Journal: Adv Sci (Weinh)

PubMed ID: 35088579

Doi: 10.1002/advs.202105226

Products & Services: Catalog Antibodies