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Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine

Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35149556

Doi: 10.1073/pnas.2119995119

Products & Services: Codon Optimization

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF melanoma

Authors: Lorey K Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P Kusnadi, Jian Kang, Claire A Martin, Peter Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D Rao, Emily J Lelliott, Karen E Sheppard, David Goode, Rodney J Hicks, Tony Tiganis, Kaylene J Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O Wickramasinghe, Richard B Pearson, Grant A McArthur

Journal: Nat Commun

PubMed ID: 35232962

Doi: 10.1038/s41467-022-28705-x

Products & Services: Mutant Libraries

Metabolic engineering of Saccharomyces cerevisiae for gram-scale diosgenin production

Authors: Liping Xu , Dong Wang , Jing Chen , Bo Li , Qingyan Li , Pingping Liu , Ying Qin , Zhubo Dai , Feiyu Fan , Xueli Zhang

Journal: Metab Eng

PubMed ID: 35085779

Doi: 10.1016/j.ymben.2022.01.013

Products & Services: Codon Optimization

A compact and simple method of achieving differential transgene expression by exploiting translational readthrough

Authors: James E Sillibourne, Giulia Agliardi, Matteo Righi, Katerina Smetanova, Grant Rowley, Simon Speller, Abigail Dolor, Katarina Lamb, Christopher Allen, Rajeev Karattil, Farhaan Parekh, Frederick Arce Vargas, Simon Thomas, Shaun Cordoba, Martin Pule

Journal: BioTechniques

PubMed ID: 35234525

Doi: 10.2144/btn-2021-0079

Products & Services: Mammalian Expression

Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling

Authors: Maricel Gomez-Soler, Marina P. Gehring, Bernhard C. Lechtenberg,Elmer Zapata-Mercado, Alyssa Ruelos,Mike W. Matsumoto,Kalina Hristova,and Elena B. Pasquale

Journal: iScience

Doi: doi.org/10.1016/j.isci.2022.103870

Products & Services: Peptide Synthesis

Global profiling of regulatory elements in the histone benzoylation pathway

Authors: Duo Wang , Fuxiang Yan , Ping Wu, Kexue Ge , Muchun Li , Tingting Li , Ying Gao , Chao Peng , Yong Chen

Journal: Nat Commun

PubMed ID: 35296687

Doi: 10.1038/s41467-022-29057-2

Products & Services: Gene Synthesis

A multifunctional enolase mediates cytoadhesion and interaction with host plasminogen and fibronectin in Mycoplasma hyorhinis

Authors: Jia Wang , Yanfei Yu , Yao Li , Shiyang Li , Li Wang , Yanna Wei , Yuzi Wu , Bala Pillay , Ademola Olufolahan Olaniran , Thamsanqa E Chiliza , Guoqing Shao , Zhixin Feng , Qiyan Xiong

Journal: Vet Res

PubMed ID: 35337383

Doi: 10.1186/s13567-022-01041-0

Products & Services: Gene Synthesis Recombinant Antibody Expression

Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression

Authors: Yvonne E Smith, Guannan Wang, Ciara L Flynn, Stephen F Madden, Owen MacEneaney, Rodrigo G B Cruz, Cathy E Richards, Hanne Jahns, Marian Brennan, Mattia Cremona, Bryan T Hennessy, Katherine Sheehan, Alexander Casucci, Faizah A Sani, Lance Hudson, Joanna Fay, Sri H Vellanki, Siobhan O'Flaherty, Marc Devocelle, Arnold D K Hill, Kieran Brennan, Saraswati Sukumar, Ann M Hopkins

Journal: Cancers (Basel)

PubMed ID: 35267611

Doi: 10.3390/cancers14051303

Products & Services: Peptide Synthesis

Distinct effects of treatment with two different interferon-alpha subtypes on HIV-1-associated T-cell activation and dysfunction in humanized mice

Authors: Saurav S Rout, Yunyun Di, Ulf Dittmer, Kathrin Sutter, Kerry J Lavender

Journal: AIDS

PubMed ID: 35084382

Doi: 10.1097/QAD.0000000000003111

Products & Services: Endotoxin Detection & Removal System

Porcine circovirus 4 rescued from an infectious clone is replicable and pathogenic in vivo

Authors: Guyu Niu, Xinwei Zhang, Weilong Ji, Si Chen, Xue Li, Lin Yang, Liying Zhang, Hongsheng Ouyang, Chang Li, Linzhu Ren

Journal: Transbound Emerg Dis

PubMed ID: 35240007

Doi: 10.1111/tbed.14498

Products & Services: Gene Synthesis