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Comprehensive engineering of a therapeutic neutralizing antibody targeting SARS-CoV-2 spike protein to neutralize escape variants

Authors: Taichi Kuramochi, Siok Wan Gan, Adrian W S Ho, Bei Wang, Nagisa Kageji, Takeru Nambu, Sayaka Iida, Momoko Okuda-Miura, Wei Shan Chia, Chiew Ying Yeo, Dan Chen, Wen-Hsin Lee, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Cheng-I Wang, Tomoyuki Igawa, Hideaki Shimada

Journal: MAbs

PubMed ID: 35293276

Doi: 10.1080/19420862.2022.2040350

Products & Services: PCR Cloning and Subcloning

USF1 Transcriptionally Regulates UGT1A3 and Promotes Lung Adenocarcinoma Progression by Regulating Neurotrophin Signaling Pathway

Authors: Yu Wang, Yun-Xia Zhao, Xiang-Wei Zhang, Yuan-Zhu Jiang, Wei Ma, Lin Zhang, Wei Dong

Journal: Front Mol Biosci

PubMed ID: 35155573

Doi: 10.3389/fmolb.2022.758968

Products & Services: Peptide Synthesis

Experimental Periodontitis Deteriorated Atherosclerosis Associated With Trimethylamine N-Oxide Metabolism in Mice

Authors: Lingling Xiao, Lingyan Huang, Xin Zhou, Dan Zhao, Yan Wang, Haiyan Min, Shiyu Song, Weibin Sun, Qian Gao, Qingang Hu, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 35118014

Doi: 10.3389/fcimb.2021.820535

Products & Services: Custom DNA/RNA Oligos

Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening

Authors: Meghan J O'Melia, Adriana Mulero-Russe, Jihoon Kim, Alyssa Pybus, Deborah DeRyckere, Levi Wood, Douglas K Graham, Edward Botchwey, Andrés J García, Susan N Thomas

Journal: Adv Mater

PubMed ID: 34989049

Doi: 10.1002/adma.202108084

Products & Services: Stable Cell Lines

RIPPA: Identification of MHC-II Binding Peptides from Antigen Using a Yeast Display-Based Approach

Authors: Rongzeng Liu, Wei Jiang, Ying Li, Elizabeth D Mellins

Journal: Curr Protoc

PubMed ID: 35041265

Doi: 10.1002/cpz1.350

Products & Services: Catalog Peptides

Antigenic and immunogenic properties of recombinant proteins consisting of two immunodominant African swine fever virus proteins fused with bacterial lipoprotein OprI

Authors: Guanglei Zhang, Wei Liu, Zhan Gao, Yanyan Chang, Sicheng Yang, Qian Peng, Sudan Ge, Bijing Kang, Junjun Shao, Huiyun Chang

Journal: Virol J

PubMed ID: 35062983

Doi: 10.1186/s12985-022-01747-9

Products & Services: Custom Vector Construction

Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Authors: Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina

Journal: Pharmaceutics

PubMed ID: 35056989

Doi: 10.3390/pharmaceutics14010093

Products & Services: Plasmid DNA Preparation PCR Cloning and Subcloning

Improving one-step scarless genome editing in by combining co-CRISPR selection with sgRNA target site masking

Authors: Katharina J Götze, Achmed Mrestani, Paula Beckmann, Knut Krohn, Diana Le Duc, Akhil Velluva, Mathias A Böhme, Manfred Heckmann, Rami Abou Jamra, Johannes R Lemke, Hendrik Bläker, Nicole Scholz, Dmitrij Ljaschenko, Tobias Langenhan

Journal: Biol Methods Protoc

PubMed ID: 35087953

Doi: 10.1093/biomethods/bpac003

Products & Services: Plasmid DNA Preparation

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities

Authors: Raffaele Iennaco, Giulio Formenti, Camilla Trovesi, Riccardo Lorenzo Rossi, Chiara Zuccato, Tiziana Lischetti, Vittoria Dickinson Bocchi, Andrea Scolz, Cristina Martínez-Labarga, Olga Rickards, Michela Pacifico, Angelica Crottini, Anders Pape Møller, Richard Zhenghuan Chen, Thomas Francis Vogt, Giulio Pavesi, David Stephen Horner, Nicola Saino, Elena Cattaneo

Journal: Cell Death Differ

PubMed ID: 34974533

Doi: 10.1038/s41418-021-00914-9

Products & Services: PCR Cloning and Subcloning

Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

Authors: Icaro Putinhon Caruso, Vitor Dos Santos Almeida, Mariana Juliani do Amaral, Guilherme Caldas de Andrade, Gabriela Rocha de Araújo, Talita Stelling de Araújo, Jéssica Moreira de Azevedo, Glauce Moreno Barbosa, Leonardo Bartkevihi, Peter Reis Bezerra, Katia Maria Dos Santos Cabral, Isabella Otênio de Lourenço, Clara L F Malizia-Motta, Aline de Luna Marques, Nathane Cunha Mebus-Antunes, Thais Cristtina Neves-Martins, Jéssica Maróstica de Sá, Karoline Sanches, Marcos Caique Santana-Silva, Ariana Azevedo Vasconcelos, Marcius da Silva Almeida, Gisele Cardoso de Amorim, Cristiane Dinis Anobom, Andrea T Da Poian, Francisco Gomes-Neto, Anderson S Pinheiro, Fabio C L Almeida

Journal: Int J Biol Macromol

PubMed ID: 35077748

Doi: 10.1016/j.ijbiomac.2022.01.121

Products & Services: PCR Cloning and Subcloning