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LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway

Authors: Ying Xing, Yang Liu, Zhong Qi, Zhengrong Liu, Xin Wang, Hongyi Zhang

Journal: Cell Mol Biol Lett

PubMed ID: 34837962

Doi: 10.1186/s11658-021-00295-4

Products & Services: Custom DNA/RNA Oligos

Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model

Authors: Monique C P Mendonça, Michael F Cronin, John F Cryan, Caitriona M O'Driscoll

Journal: Eur J Pharm Biopharm

PubMed ID: 34793942

Doi: 10.1016/j.ejpb.2021.11.003

Products & Services: Catalog Peptides

Endotoxin Acts Synergistically With Clostridioides difficile Toxin B to Increase Interleukin 1β Production: A Potential Role for the Intestinal Biome in Modifying the Severity of C difficile Colitis

Authors: Pyae Htwe, Htay Aung, Bohm Kywe, Phyu T Niang, Thar Sann Oo, Sindhu Monhandas, Libusha Kelly, David L Goldman

Journal: J Infect Dis

PubMed ID: 33780547

Doi: 10.1093/infdis/jiab165

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Mitochondrial Localization Signal of Porcine Circovirus Type 2 Capsid Protein Plays a Critical Role in Cap-Induced Apoptosis

Authors: Wanting Yu, Yuao Sun, Qing He, Chaoying Sun, Tian Dong, Luhua Zhang, Yang Zhan, Naidong Wang, Yi Yang, Yujie Sun

Journal: Vet Sci

PubMed ID: 34822645

Doi: 10.3390/vetsci8110272

Products & Services: Custom Vector Construction

TGF-β1-overexpressing mesenchymal stem cells reciprocally regulate Th17/Treg cells by regulating the expression of IFN-γ

Authors: Ruixue Li, Renyong Wang, Shijie Zhong, Farhan Asghar, Tiehan Li, Lei Zhu, Hong Zhu

Journal: Open Life Sci

PubMed ID: 34761110

Doi: 10.1515/biol-2021-0118

Products & Services: Custom Vector Construction

Potential role of BAY11-7082, a NF-κB blocker inhibiting experimental autoimmune encephalomyelitis in C57BL/6J mice via declining NLRP3 inflammasomes

Authors: Yue Lang, Fengna Chu, Lingling Liu, Chao Zheng, Chunrong Li, Donghui Shen, Shan Liu, Weiguanliu Zhang, Li Cui, Jie Zhu

Journal: Clin Exp Immunol

PubMed ID: 35020839

Doi: 10.1093/cei/uxab022

Products & Services: Peptide Synthesis

Inducing I and phase 1 repolarization of the cardiac action potential with a Kv43/KChIP21 bicistronic transgene

Authors: Nan Wang, Eef Dries, Ewan D Fowler, Stephen C Harmer, Jules C Hancox, Mark B Cannell

Journal: J Mol Cell Cardiol

PubMed ID: 34823101

Doi: 10.1016/j.yjmcc.2021.11.004

Products & Services: DNA Sequencing

Refinement and Neutralization Evaluation of the F(ab') Type of Antivenom against the Deadly Jellyfish Toxins

Authors: Rongfeng Li, Huahua Yu, Aoyu Li, Chunlin Yu, Pengcheng Li

Journal: Int J Mol Sci

PubMed ID: 34884477

Doi: 10.3390/ijms222312672

Products & Services: Protein and Antibody Isolation

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

Authors: Mohamad-Gabriel Alameh, István Tombácz, Emily Bettini, Katlyn Lederer, Chutamath Sittplangkoon, Joel R Wilmore, Brian T Gaudette, Ousamah Y Soliman, Matthew Pine, Philip Hicks, Tomaz B Manzoni, James J Knox, John L Johnson, Dorottya Laczkó, Hiromi Muramatsu, Benjamin Davis, Wenzhao Meng, Aaron M Rosenfeld, Shirin Strohmeier, Paulo J C Lin, Barbara L Mui, Ying K Tam, Katalin Karikó, Alain Jacquet, Florian Krammer, Paul Bates, Michael P Cancro, Drew Weissman, Eline T Luning Prak, David Allman, Michela Locci, Norbert Pardi

Journal: Immunity

PubMed ID: 34852217

Doi: 10.1016/j.immuni.2021.11.001

Products & Services: Recombinant Antibody Expression

Mediates Hormonally Regulated Dominance Rank in a Social Bee

Authors: Atul Pandey, Guy Bloch

Journal: Biology (Basel)

PubMed ID: 34827180

Doi: 10.3390/biology10111188

Products & Services: Molecular Biology Tools