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Ultrasensitive CRISPR/Cas12a-Driven SERS Biosensor for On-Site Nucleic Acid Detection and Its Application to Milk Authenticity Testing

Authors: Ruiyuan Pan, Jianghua Liu, Panxue Wang, Di Wu, Jian Chen, Yongning Wu, Guoliang Li

Journal: J Agric Food Chem

PubMed ID: 35380812

Doi: 10.1021/acs.jafc.1c08262

Products & Services: Custom DNA/RNA Oligos

Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells

Authors: Kareem A Heslop, Pieter Burger, Christiana Kappler, Ashish K Solanki, Monika Gooz, Yuri K Peterson, Catherine Mills, Thomas Benton, Stephen A Duncan, Patrick M Woster, Eduardo N Maldonado

Journal: Biomed Pharmacother

PubMed ID: 35447542

Doi: 10.1016/j.biopha.2022.112928

Products & Services: Plasmid DNA Preparation

The development of a candidate of desensitization vaccines against Der f 2 nearly without IgE-binding activity

Authors: Xiao-Jing Ling, Chen Pan, Ling-Xiao Tan, Ying Zhu, Yu-Xing Yang, Xiao-Fei Zeng, Jin-Lyu Sun, Ji-Fu Wei, Chen Lu

Journal: Immunobiology

PubMed ID: 35580444

Doi: 10.1016/j.imbio.2022.152217

Products & Services: Protein and Antibody Isolation

Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis

Authors: Takafumi Kato, Giorgia Radicioni, Micah J Papanikolas, Georgi V Stoychev, Matthew R Markovetz, Kazuhiro Aoki, Melody Porterfield, Kenichi Okuda, Selene M Barbosa Cardenas, Rodney C Gilmore, Cameron B Morrison, Camille Ehre, Kimberlie A Burns, Kristen K White, Tara A Brennan, Henry P Goodell, Holly Thacker, Henry T Loznev, Lawrence J Forsberg, Takahide Nagase, Michael Rubinstein, Scott H Randell, Michael Tiemeyer, David B Hill, Mehmet Kesimer, Wanda K O'Neal, Stephen T Ballard, Ronit Freeman, Brian Button, Richard C Boucher

Journal: Sci Adv

PubMed ID: 35363522

Doi: 10.1126/sciadv.abm9718

Products & Services: Plasmid DNA Preparation

First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine

Authors: Luis Martínez, Iker Malaina, David Salcines-Cuevas, Héctor Terán-Navarro, Andrea Zeoli, Santos Alonso, Ildefonso M De la Fuente, Elena Gonzalez-Lopez, J Gonzalo Ocejo-Vinyals, Mónica Gozalo-Margüello, Jorge Calvo-Montes, Carmen Alvarez-Dominguez

Journal: Sci Rep

PubMed ID: 35440789

Doi: 10.1038/s41598-022-09615-w

The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor

Authors: Francisco J Fernández, Jorge Santos-López, Rubén Martínez-Barricarte, Javier Querol-García, Héctor Martín-Merinero, Sergio Navas-Yuste, Martin Savko, William E Shepard, Santiago Rodríguez de Córdoba, M Cristina Vega

Journal: Nat Commun

PubMed ID: 35413960

Doi: 10.1038/s41467-022-29580-2

Products & Services: Plasmid DNA Preparation

Measles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract

Authors: Drishya Kurup, Christoph Wirblich, Rachael Lambert, Leila Zabihi Diba, Benjamin E Leiby, Matthias J Schnell

Journal: npj Vaccines

PubMed ID: 35440656

Doi: 10.1038/s41541-022-00464-2

Products & Services: Gene Synthesis

Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action

Authors: Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A Zubarev, Stig Linder, Pádraig D'Arcy

Journal: Front Oncol

PubMed ID: 35530310

Doi: 10.3389/fonc.2022.852980

Products & Services: Oligo pool

Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota

Authors: Matthew P Ostrowski, Sabina Leanti La Rosa, Benoit J Kunath, Andrew Robertson, Gabriel Pereira, Live H Hagen, Neha J Varghese, Ling Qiu, Tianming Yao, Gabrielle Flint, James Li, Sean P McDonald, Duna Buttner, Nicholas A Pudlo, Matthew K Schnizlein, Vincent B Young, Harry Brumer, Thomas M Schmidt, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Bruce Hamaker, Emiley A Eloe-Fadrosh, Ashootosh Tripathi, Phillip B Pope, Eric C Martens

Journal: Nat Microbiol

PubMed ID: 35365790

Doi: 10.1038/s41564-022-01093-0

Products & Services: Gene Fragments

Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF-κB activation through upregulating sirtuin 7 in dental pulp fibroblasts

Authors: Xiaochen Liu, Chunmeng Wang, Liping Pang, Liangliang Pan, Qi Zhang

Journal: Cell Prolif

PubMed ID: 35411569

Doi: 10.1111/cpr.13227

Products & Services: Recombinant Proteins