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FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P-dependent switch

Authors: Nathan R Zaccai, Zuzana Kadlecova, Veronica Kane Dickson, Kseniya Korobchevskaya, Jan Kamenicky, Oleksiy Kovtun, Perunthottathu K Umasankar, Antoni G Wrobel, Jonathan G G Kaufman, Sally R Gray, Kun Qu, Philip R Evans, Marco Fritzsche, Filip Sroubek, Stefan Höning, John A G Briggs, Bernard T Kelly, David J Owen, Linton M Traub

Journal: Sci Adv

PubMed ID: 35486718

Doi: 10.1126/sciadv.abn2018

Products & Services: Plasmid DNA Preparation

Monoclonal antibody targeting the conserved region of the SARS-CoV-2 spike protein to overcome viral variants

Authors: Wan-Ling Wu, Chen-Yi Chiang, Szu-Chia Lai, Chia-Yi Yu, Yu-Ling Huang, Hung-Chun Liao, Ching-Len Liao, Hsin-Wei Chen, Shih-Jen Liu

Journal: JCI Insight

PubMed ID: 35290246

Doi: 10.1172/jci.insight.157597

Products & Services: Mammalian Expression

Metabolic engineering of yeasts for green and sustainable production of bioactive ginsenosides F2 and 3,20-Di--Glc-DM

Authors: Fenglin Jiang, Chen Zhou, Yan Li, Haidong Deng, Ting Gong, Jingjing Chen, Tianjiao Chen, Jinling Yang, Ping Zhu

Journal: Acta Pharm Sin B

PubMed ID: 35865098

Doi: 10.1016/j.apsb.2022.04.012

Products & Services: Mutant Libraries

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

Authors: Kai S Yang, Syuan-Ting Alex Kuo, Lauren R Blankenship, Zhi Zachary Geng, Shuhua G Li, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu

Journal: Curr Res Chem Biol

PubMed ID: 35815070

Doi: 10.1016/j.crchbi.2022.100025

Products & Services: Protein and Antibody Isolation

Non-homologous End Joining-Mediated Insertional Mutagenesis Reveals a Novel Target for Enhancing Fatty Alcohols Production in

Authors: Mengxu Li, Jinlai Zhang, Qiuyan Bai, Lixia Fang, Hao Song, Yingxiu Cao

Journal: Front Microbiol

PubMed ID: 35547152

Doi: 10.3389/fmicb.2022.898884

Products & Services: Codon Optimization

Inhibition of PRMT5 by market drugs as a novel cancer therapeutic avenue

Authors: Lakshmi Prabhu, Matthew Martin, Lan Chen, Özlem Demir, Jiamin Jin, Xiumei Huang, Aishat Motolani, Mengyao Sun, Guanglong Jiang, Harikrishna Nakshatri, Melissa L Fishel, Steven Sun, Ahmad Safa, Rommie E Amaro, Mark R Kelley, Yunlong Liu, Zhong-Yin Zhang, Tao Lu

Journal: Genes Dis

PubMed ID: 37013054

Doi: 10.1016/j.gendis.2022.04.001

Products & Services: Protein and Antibody Isolation

Identification of Single-Molecule Catecholamine Enantiomers Using a Programmable Nanopore

Authors: Wendong Jia, Chengzhen Hu, Yuqin Wang, Yao Liu, Liying Wang, Shanyu Zhang, Qiang Zhu, Yuming Gu, Panke Zhang, Jing Ma, Hong-Yuan Chen, Shuo Huang

Journal: ACS Nano

PubMed ID: 35394745

Doi: 10.1021/acsnano.2c01017

Products & Services: Gene Synthesis

A Nanopore Based Molnupiravir Sensor

Authors: Wendong Jia , Chengzhen Hu , Yuqin Wang , Panke Zhang , Hong-Yuan Chen , Shuo Huang

Journal: ACS Sens

PubMed ID: 35427117

Doi: 10.1021/acssensors.2c00447

Products & Services: Plasmid DNA Preparation

USP14-regulated allostery of the human proteasome by time-resolved cryo-EM

Authors: Shuwen Zhang , Shitao Zou , Deyao Yin , Lihong Zhao , Daniel Finley , Zhaolong Wu , Youdong Mao

Journal: Nature

PubMed ID: 35477760

Doi: 10.1038/s41586-022-04671-8

Products & Services: Gene Synthesis

A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models

Authors: Anurupa A Ghosh, Dinesh Kumar Verma, Gabriela Cabrera, Kwadwo Ofori, Karina Hernandez-Quijada, Jae-Kwan Kim, Joo Hee Chung, Michael Moore, Sung Hwan Moon, Jong Bok Seo, Yong-Hwan Kim

Journal: Int J Mol Sci

PubMed ID: 35457082

Doi: 10.3390/ijms23084262

Products & Services: Protein Electrophoresis and Western