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Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors

Authors: Ru Dong, Cheng Zhang, Chao Wang, Xin Zhou, Wen Li, Jin-Yang Zhang, Min Wang, Yong Xu, Li-Ping Sun

Journal: Bioorg Med Chem

PubMed ID: 34999525

Doi: 10.1016/j.bmc.2021.116592

Products & Services: Catalog Antibodies

Author Correction: Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro

Authors: Trine Lisberg Toft-Bertelsen, Mads Gravers Jeppesen, Eva Tzortzini, Kai Xue, Karin Giller, Stefan Becker, Amer Mujezinovic, Bo Hjorth Bentzen, Loren B Andreas, Antonios Kolocouris, Thomas Nitschke Kledal, Mette Marie Rosenkilde

Journal: Commun Biol

PubMed ID: 34893762

Doi: 10.1038/s42003-021-02940-2

Products & Services: Gene Synthesis

SlpB Protein Enhances the Probiotic Potential of NCDO 2118 in Colitis Mice Model

Authors: Giovanna A Belo, Bárbara F Cordeiro, Emiliano R Oliveira, Marina P Braga, Sara H da Silva, Bruno G Costa, Flaviano Dos S Martins, Gwénaël Jan, Yves Le Loir, Alfonso Gala-García, Enio Ferreira, Vasco Azevedo, Fillipe L R do Carmo

Journal: Front Pharmacol

PubMed ID: 34987390

Doi: 10.3389/fphar.2021.755825

Products & Services: Gene Synthesis

Immunization with short peptide particles reveals a functional CD8 T-cell neoepitope in a murine renal carcinoma model

Authors: Xuedan He, Shiqi Zhou, Melissa Dolan, Yuhao Shi, Jianxin Wang, Breandan Quinn, Dushyant Jahagirdar, Wei-Chiao Huang, Moriya Tsuji, Roberto Pili, Fumito Ito, Joaquin Ortega, Scott I Abrams, John M L Ebos, Jonathan F Lovell

Journal: J Immunother Cancer

PubMed ID: 34862254

Doi: 10.1136/jitc-2021-003101

Products & Services: Peptide Synthesis

Glycan Masking of Epitopes in the NTD and RBD of the Spike Protein Elicits Broadly Neutralizing Antibodies Against SARS-CoV-2 Variants

Authors: Wei-Shuo Lin, I-Chen Chen, Hui-Chen Chen, Yi-Chien Lee, Suh-Chin Wu

Journal: Front Immunol

PubMed ID: 34925381

Doi: 10.3389/fimmu.2021.795741

Products & Services: Mutagenesis Services

Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis of Proteins

Authors: Clara L Kielkopf, William Bauer, Ina L Urbatsch

Journal: Cold Spring Harb Protoc

PubMed ID: 34853120

Doi: 10.1101/pdb.prot102228

Products & Services: Protein and Antibody Isolation

CFAP61 is required for sperm flagellum formation and male fertility in human and mouse

Authors: Siyu Liu, Jintao Zhang, Zine Eddine Kherraf, Shuya Sun, Xin Zhang, Caroline Cazin, Charles Coutton, Raoudha Zouari, Shuqin Zhao, Fan Hu, Selima Fourati Ben Mustapha, Christophe Arnoult, Pierre F Ray, Mingxi Liu

Journal: Development

PubMed ID: 34792097

Doi: 10.1242/dev.199805

Products & Services: Plasmid DNA Preparation

Phylogeny of Leptographium qinlingensis cytochrome P450 genes and transcription levels of six CYPs in response to different nutrition media or terpenoids

Authors: Lulu Dai, Jie Zheng, Jiaqi Ye, Hui Chen

Journal: Arch Microbiol

PubMed ID: 34894279

Doi: 10.1007/s00203-021-02616-9

Products & Services: DNA Sequencing

De novo design of a transcription factor for a progesterone biosensor

Authors: Kun Liu, Yunsen Zhang, Ke Liu, Yunqiu Zhao, Bei Gao, Xinyi Tao, Ming Zhao, Feng-Qing Wang, Dongzhi Wei

Journal: Biosens Bioelectron

PubMed ID: 35134684

Doi: 10.1016/j.bios.2021.113897

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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

Authors: Zhenghai Tang, Dominique Davidson, Rui Li, Ming-Chao Zhong, Jin Qian, Jun Chen, André Veillette

Journal: Cell Rep

PubMed ID: 34910922

Doi: 10.1016/j.celrep.2021.110111

Products & Services: Custom Vector Construction