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Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy

Authors: Hassan Issafras, Shilong Fan, Chi-Ling Tseng, Yunchih Cheng, Peihua Lin, Lisa Xiao, Yun-Ju Huang, Chih-Hsiang Tu, Ya-Chin Hsiao, Min Li, Yen-Hsiao Chen, Chien-Hsin Ho, Ou Li, Yanling Wang, Sandra Chen, Zhenyu Ji, Eric Zhang, Yi-Ting Mao, Eugene Liu, Shumin Yang, Weidong Jiang

Journal: PLoS ONE

PubMed ID: 34972111

Doi: 10.1371/journal.pone.0257972

Products & Services: Gene Fragments

Impact of Molecular Modifications on the Immunogenicity and Efficacy of Recombinant Raccoon Poxvirus-Vectored Rabies Vaccine Candidates in Mice

Authors: Carly M Malavé, Jaime Lopera-Madrid, Lex G Medina-Magües, Tonie E Rocke, Jorge E Osorio

Journal: Vaccines (Basel)

PubMed ID: 34960182

Doi: 10.3390/vaccines9121436

Products & Services: Plasmid DNA Preparation

Simultaneous binding of the N- and C-terminal cytoplasmic domains of aquaporin 4 to calmodulin

Authors: Hiroaki Ishida, Hans J Vogel, Alex C Conner, Philip Kitchen, Roslyn M Bill, Justin A MacDonald

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 34890582

Doi: 10.1016/j.bbamem.2021.183837

Products & Services: Peptide Synthesis

Development of a high-throughput RT-PCR based viral infectivity assay for monitoring the stability of a replicating recombinant Lymphocytic Choriomeningitis viral vector

Authors: Vineet Gupta, Lorena R Antunez, Soraia Saleh-Birdjandi, Ozan S Kumru, Richard Pospisil, Anders Lilja, Gerhard Fuhrmann, Lee Smith, David B Volkin, Sangeeta B Joshi

Journal: J Virol Methods

PubMed ID: 34954306

Doi: 10.1016/j.jviromet.2021.114440

Products & Services: Protein and Antibody Isolation

Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials

Authors: Jill Whitley, Christopher Zwolinski, Christian Denis, Maureen Maughan, Leonie Hayles, David Clarke, Meghan Snare, Hong Liao, Sean Chiou, Tina Marmura, Holly Zoeller, Ben Hudson, John Peart, Monica Johnson, Amelia Karlsson, Yunfei Wang, Cynthia Nagle, Cherell Harris, Daniel Tonkin, Stephanie Fraser, Lieza Capiz, Christina L Zeno, Yvonne Meli, Diana Martik, Daniel A Ozaki, Amy Caparoni, Jason E Dickens, Drew Weissman, Kevin O Saunders, Barton F Haynes, Gregory D Sempowski, Thomas N Denny, Matthew R Johnson

Journal: Transl Res

PubMed ID: 34871810

Doi: 10.1016/j.trsl.2021.11.009

Products & Services: Plasmid DNA Preparation

Engineered Sphingomonas sp KT-1 PahZ1 monomers efficiently degrade poly(aspartic acid)

Authors: Timothy Lamantia, Amanda Jansch, Justin D Marsee, Mitch H Weiland, Justin M Miller

Journal: Biophys Chem

PubMed ID: 34953381

Doi: 10.1016/j.bpc.2021.106745

Products & Services: Mutagenesis Services

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis

Authors: Lulu Wang, Wenchen Pu, Chun Wang, Lang Lei, Houxuan Li

Journal: J Oral Microbiol

PubMed ID: 34992737

Doi: 10.1080/20002297.2021.2015130

Products & Services: Custom DNA/RNA Oligos

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis

Authors: Lulu Wang, Wenchen Pu, Chun Wang, Lang Lei, Houxuan Li

Journal: J Oral Microbiol

PubMed ID: 34992737

Doi: 10.1080/20002297.2021.2015130

Products & Services: Custom DNA/RNA Oligos

An immunochromatographic assay utilizing magnetic nanoparticles to detect major peanut allergen Ara h 1 in processed foods

Authors: Hsin-Yi Yin, Yi-Ting Li, Wen-Che Tsai, Hong-Yu Dai, Hsiao-Wei Wen

Journal: Food Chem

PubMed ID: 34952385

Doi: 10.1016/j.foodchem.2021.131844

Products & Services: Peptide Synthesis

GST-Perfringolysin O production for the localization and quantification of membrane cholesterol in human and mouse brain and liver

Authors: Leire Goicoechea, Fabian Arenas, Fernanda Castro, Susana Nuñez, Sandra Torres, Carmen Garcia-Ruiz, José C Fernandez-Checa

Journal: STAR Protoc

PubMed ID: 35024626

Doi: 10.1016/j.xpro.2021.101068

Products & Services: Custom DNA/RNA Oligos