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SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity

Authors: Sandile Cele, Farina Karim, Gila Lustig, James Emmanuel San, Tandile Hermanus, Houriiyah Tegally, Jumari Snyman, Thandeka Moyo-Gwete, Eduan Wilkinson, Mallory Bernstein, Khadija Khan, Shi-Hsia Hwa, Sasha W Tilles, Lavanya Singh, Jennifer Giandhari, Ntombifuthi Mthabela, Matilda Mazibuko, Yashica Ganga, Bernadett I Gosnell, Salim Abdool Karim, Willem Hanekom, Wesley C Van Voorhis, Thumbi Ndung'u, Richard J Lessells, Penny L Moore, Mahomed-Yunus S Moosa, Tulio de Oliveira, Alex Sigal

Journal: medrxiv

PubMed ID: 34909798

Doi: 10.1101/2021.09.14.21263564

Products & Services: Monoclonal Antibody Services

Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic

Authors: Justin R Randall, Gillian Davidson, Renee M Fleeman, Santos A Acosta, Ian M Riddington, T Jeffrey Cole, Cory D DuPai, Bryan W Davies

Journal: iScience

PubMed ID: 35005555

Doi: 10.1016/j.isci.2021.103611

Products & Services: Peptide Synthesis

Mechanistic Insights into the Preference for Tandem Binding Sites in DNA Recognition by FOXM1

Authors: Huajun Zhang, Shuyan Dai, Xujun Liang, Jun Li, Yongheng Chen

Journal: J Mol Biol

PubMed ID: 34973238

Doi: 10.1016/j.jmb.2021.167426

Products & Services: Custom DNA/RNA Oligos

Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography

Authors: Johannes Elferich, Sarah Clark, Jingpeng Ge, April Goehring, Aya Matsui, Eric Gouaux

Journal: Elife

PubMed ID: 34964715

Doi: 10.7554/eLife.74512

Products & Services: Polyclonal Antibody Services

Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy

Authors: Hassan Issafras, Shilong Fan, Chi-Ling Tseng, Yunchih Cheng, Peihua Lin, Lisa Xiao, Yun-Ju Huang, Chih-Hsiang Tu, Ya-Chin Hsiao, Min Li, Yen-Hsiao Chen, Chien-Hsin Ho, Ou Li, Yanling Wang, Sandra Chen, Zhenyu Ji, Eric Zhang, Yi-Ting Mao, Eugene Liu, Shumin Yang, Weidong Jiang

Journal: PLoS ONE

PubMed ID: 34972111

Doi: 10.1371/journal.pone.0257972

Products & Services: Gene Fragments

Impact of Molecular Modifications on the Immunogenicity and Efficacy of Recombinant Raccoon Poxvirus-Vectored Rabies Vaccine Candidates in Mice

Authors: Carly M Malavé, Jaime Lopera-Madrid, Lex G Medina-Magües, Tonie E Rocke, Jorge E Osorio

Journal: Vaccines (Basel)

PubMed ID: 34960182

Doi: 10.3390/vaccines9121436

Products & Services: Plasmid DNA Preparation

Development of a Highly Sensitive Luciferase-Based Reporter System To Study Two-Step Protein Secretion in Cyanobacteria

Authors: David A Russo, Julie A Z Zedler, Fabian D Conradi, Nils Schuergers, Poul Erik Jensen, Conrad W Mullineaux, Annegret Wilde, Georg Pohnert

Journal: J Bacteriol

PubMed ID: 34898262

Doi: 10.1128/JB.00504-21

Products & Services: Gene Synthesis

Different response of Acipenser gueldenstaedtii CRP/SAP and SAA to bacterial challenge and chronic thermal stress sheds light on the innate immune system of sturgeons

Authors: Marcio Aversa-Marnai, Mauricio Castellano, Ignacio Quartiani, Daniel Conijesky, Alejandro Perretta, Andrea Villarino, Valeria Silva-Álvarez, Ana María Ferreira

Journal: Fish Shellfish Immunol

PubMed ID: 34971737

Doi: 10.1016/j.fsi.2021.12.029

Products & Services: Recombinant Proteins

Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patients

Authors: Qihong Yan, Ping He, Xiaohan Huang, Kun Luo, Yudi Zhang, Haisu Yi, Qian Wang, Feng Li, Ruitian Hou, Xiaodi Fan, Pingchao Li, Xinglong Liu, Huan Liang, Yijun Deng, Zhaoming Chen, Yunfei Chen, Xiaoneng Mo, Liqiang Feng, Xiaoli Xiong, Song Li, Jian Han, Linbing Qu, Xuefeng Niu, Ling Chen

Journal: Emerg Microbes Infect

PubMed ID: 33944697

Doi: 10.1080/22221751.2021.1925594

Products & Services: Serology SARS-Cov-2 detection kits

Lactobacillus lactis and Pediococcus pentosaceus-driven reprogramming of gut microbiome and metabolome ameliorates the progression of non-alcoholic fatty liver disease

Authors: Jeong Seok Yu, Gi Soo Youn, Jieun Choi, Chang-Ho Kim, Byung Yong Kim, Seung-Jo Yang, Je Hee Lee, Tae-Sik Park, Byoung Kook Kim, Yeon Bee Kim, Seong Woon Roh, Byeong Hyun Min, Hee Jin Park, Sang Jun Yoon, Na Young Lee, Ye Rin Choi, Hyeong Seob Kim, Haripriya Gupta, Hotaik Sung, Sang Hak Han, Ki Tae Suk, Do Yup Lee

Journal: Clin Transl Med

PubMed ID: 34965016

Doi: 10.1002/ctm2.634

Products & Services: Protein and Antibody Reagents