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Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood

Authors: Tetsuhiro Horie, Kazuya Fukasawa, Takanori Yamada, Seiya Mizuno, Takashi Iezaki, Kazuya Tokumura, Sayuki Iwahashi, Shiho Sakai, Akane Suzuki, Takuya Kubo, Ryoma Osumi, Akane Tomizawa, Hiroki Ochi, Shingo Sato, Katsuyuki Kaneda, Satoru Takahashi, Eiichi Hinoi

Journal: Stem Cells

PubMed ID: 35304894

Doi: 10.1093/stmcls/sxac011

Products & Services: Polyclonal Antibody Services

Dynamic modulation of enzyme activity by synthetic CRISPR-Cas6 endonucleases

Authors: Alexander A Mitkas, Mauricio Valverde, Wilfred Chen

Journal: Nat Chem Biol

PubMed ID: 35468950

Doi: 10.1038/s41589-022-01005-7

Products & Services: Monoclonal Antibody Services

Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies

Authors: Manish Jain, Jordan Bouilloux, Ines Borrego, Stéphane Cook, Hubert van den Bergh, Norbert Lange, Georges Wagnieres, Marie-Noelle Giraud

Journal: Pharmaceuticals (Basel)

PubMed ID: 35631388

Doi: 10.3390/ph15050564

Products & Services: Chemicals

Tuning the Sensitivity of Genetically Encoded Fluorescent Potassium Indicators through Structure-Guided and Genome Mining Strategies

Authors: Cristina C Torres Cabán, Minghan Yang, Cuixin Lai, Lina Yang, Fedor V Subach, Brian O Smith, Kiryl D Piatkevich, Edward S Boyden

Journal: ACS Sens

PubMed ID: 35427452

Doi: 10.1021/acssensors.1c02201

Products & Services: Custom Vector Construction

Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants

Authors: Jason Z Zhang, Hsien-Wei Yeh, Alexandra C Walls, Basile I M Wicky, Kaitlin R Sprouse, Laura A VanBlargan, Rebecca Treger, Alfredo Quijano-Rubio, Minh N Pham, John C Kraft, Ian C Haydon, Wei Yang, Michelle DeWitt, John E Bowen, Cameron M Chow, Lauren Carter, Rashmi Ravichandran, Mark H Wener, Lance Stewart, David Veesler, Michael S Diamond, Alexander L Greninger, David M Koelle, David Baker

Journal: Nat Biotechnol

PubMed ID: 35484405

Doi: 10.1038/s41587-022-01280-8

Products & Services: Catalog Peptides

Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway

Authors: Xiaofang Wei, Juan Tan, Hui Gao

Journal: Bioengineered

PubMed ID: 35383535

Doi: 10.1080/21655979.2022.2060626

Products & Services: Custom DNA/RNA Oligos

A third dose of mRNA-1273 vaccine improves SARS-CoV-2 immunity in HCT recipients with low antibody response after 2 doses

Authors: Elena Pettini, Annalisa Ciabattini, Gabiria Pastore, Jacopo Polvere, Simone Lucchesi, Fabio Fiorino, Francesca Montagnani, Alessandro Bucalossi, Monica Tozzi, Giuseppe Marotta, Donata Medaglini

Journal: Blood Adv

PubMed ID: 35073574

Doi: 10.1182/bloodadvances.2021006599

The recombinant defensin/HSA fusion protein that inhibits NF-κb associated with intensive macropinocytosis shows potent efficacy against pancreatic cancer

Authors: Yi-Bo Du, Xiao-Fei Wang, Xiu-Jun Liu, Yi Li, Qing-Fang Miao, Min Jiang, Wei-Jin Sheng, Yong-Su Zhen

Journal: Biochem Pharmacol

PubMed ID: 35489393

Doi: 10.1016/j.bcp.2022.115057

Products & Services: Recombinant Antibody Expression

Functional differentiation of three pheromone binding proteins in Orthaga achatina using mixed-type sex pheromones

Authors: Yu-Xiao Si, Jin-Meng Guo, Hui Liao, Yu Li, Yu Ma, Yu-Wei Zhu, Zhi-Qiang Wei, Shuang-Lin Dong, Qi Yan

Journal: Pestic Biochem Physiol

PubMed ID: 35715036

Doi: 10.1016/j.pestbp.2022.105097

Products & Services: Protein and Antibody Isolation

Hypomethylation-mediated upregulation of the WASF2 promoter region correlates with poor clinical outcomes in hepatocellular carcinoma

Authors: Hye Ri Ahn, Geum Ok Baek, Moon Gyeong Yoon, Ju A Son, Jung Hwan Yoon, Jae Youn Cheong, Hyo Jung Cho, Ho Chul Kang, Jung Woo Eun, Soon Sun Kim

Journal: J Exp Clin Cancer Res

PubMed ID: 35477411

Doi: 10.1186/s13046-022-02365-7

Products & Services: Custom Vector Construction