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DNA tile self-assembly driven by antibody-mediated four-way branch migration

Authors: Xingdi Cui, Yuan Liu, Qiang Zhang

Journal: Analyst

PubMed ID: 35467671

Doi: 10.1039/d1an02273c

Products & Services: Gene Synthesis

A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME

Authors: Xuejun Xiao, Yan Peng, Zheyue Wang, Louqian Zhang, Tingting Yang, Yangyang Sun, Yufeng Chen, Wenqing Zhang, Xinxia Chang, Wen Huang, Shuning Tian, Zhenqing Feng, Nabi Xinhua, Qi Tang, Yuan Mao

Journal: Pharmacol Res

PubMed ID: 35605813

Doi: 10.1016/j.phrs.2022.106269

Products & Services: Protein and Antibody Isolation

The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

Authors: Peter John, Marc C Pulanco, Phillip M Galbo, Yao Wei, Kim C Ohaegbulam, Deyou Zheng, Xingxing Zang

Journal: Nat Commun

PubMed ID: 35523809

Doi: 10.1038/s41467-022-30143-8

Products & Services: Protein and Antibody Isolation

Enhancement of Farnesoid X Receptor Inhibits Migration, Adhesion and Angiogenesis through Proteasome Degradation and VEGF Reduction in Bladder Cancers

Authors: Chien-Rui Lai, Hisao-Hsien Wang, Hsin-Han Chang, Yu-Ling Tsai, Wen-Chiuan Tsai, Chen-Ray Lee, Chih-Ying Changchien, Yu-Chen Cheng, Sheng-Tang Wu, Ying Chen

Journal: Int J Mol Sci

PubMed ID: 35563650

Doi: 10.3390/ijms23095259

Products & Services: PCR Cloning and Subcloning

Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT

Authors: Sarah Heckmatt Shafik, Sashika Natasha Richards, Ben Corry, Rowena Elizabeth Martin

Journal: PLoS Biol

PubMed ID: 35507548

Doi: 10.1371/journal.pbio.3001616

Products & Services: Custom Vector Construction

Thermostable H1 hemagglutinin stem with M2e epitopes provides broad cross-protection against group1 and 2 influenza A viruses

Authors: Jeeva Subbbiah, Judy Oh, Ki-Hye Kim, Chong Hyun Shin, Bo Ryoung Park, Noopur Bhatnagar, Yu-Jin Jung, Youri Lee, Bao-Zhong Wang, Baik-Lin Seong, Sang-Moo Kang

Journal: Mol Ther Methods Clin Dev

PubMed ID: 35755946

Doi: 10.1016/j.omtm.2022.05.007

Products & Services: Custom Vector Construction

Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain

Authors: Sucharita Sarkar, Brent Runge, Ryan W Russell, Kumar Tekwani Movellan, Daniel Calero, Somayeh Zeinalilathori, Caitlin M Quinn, Manman Lu, Guillermo Calero, Angela M Gronenborn, Tatyana Polenova

Journal: J Am Chem Soc

PubMed ID: 35638584

Doi: 10.1021/jacs.2c03320

Products & Services: Codon Optimization

Expression and purification of the NG domain from human SRα, a key component of the Signal Recognition Particle (SRP) receptor

Authors: Madeline S McRae, Brendon Wang, RobertM G Hyson, Rezwan Siddiquee, Anthony P Duff, Sandro F Ataide, Ann H Kwan

Journal: Protein Expr Purif

PubMed ID: 35640773

Doi: 10.1016/j.pep.2022.106121

Products & Services: Custom Vector Construction

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP

Authors: Andrea Pawellek; Ursula Ryder; Triin Tammsalu; Lewis J King; Helmi Kreinin; Tony Ly; Ronald T Hay; Richard C Hartley; Angus I Lamond

Journal: Elife

PubMed ID: 28884683

Doi: 10.7554/eLife.27402

A model for drug transport across two membranes of Gram-negative bacteria by an MFS tripartite assembly

Authors: Zhaojun Zhong; Tuerxunjiang Maimaiti; Matthew L. Jackson; Rui Dong; Xueyan Gao; Qing Ouyang; Wenqian Wang; Jinliang Guo; Shangrong Li; Wenyu Shang; Huajun Liu; Hongnian Jiang; Shuo Zhang; Ulrich Zachariae; Ben F. Luisi; Yanjie Chao; Dijun Du

Journal: Nature Communications

PubMed ID: 41839863

Doi: 10.1038/s41467-026-70500-5

Products & Services: Protein and Antibody Isolation