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Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral , Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme

Authors: Nicole E Avalon, Jordan Nafie, Carolina De Marco Verissimo, Luke C Warrensford, Sarah G Dietrick, Amanda R Pittman, Ryan M Young, Fiona L Kearns, Tracess Smalley, Jennifer M Binning, John P Dalton, Mark P Johnson, H Lee Woodcock, A Louise Allcock, Bill J Baker

Journal: J Nat Prod

PubMed ID: 35549259

Doi: 10.1021/acs.jnatprod.2c00054

Products & Services: Custom Vector Construction

A paper-based optical sensor for the screening of viruses through the cysteine residues of their surface proteins: A proof of concept on the detection of coronavirus infection

Authors: Mahnaz D Gholami, Kristyan Guppy-Coles, Serena Nihal, Daman Langguth, Prashant Sonar, Godwin A Ayoko, Chamindie Punyadeera, Emad L Izake

Journal: Talanta

PubMed ID: 35660992

Doi: 10.1016/j.talanta.2022.123630

Products & Services: Recombinant Antibody Expression

Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant

Authors: Kanwal Khan, Salman Ali Khan, Khurshid Jalal, Zaheer Ul-Haq, Reaz Uddin

Journal: Virology

PubMed ID: 35576833

Doi: 10.1016/j.virol.2022.05.001

Products & Services: Peptide Synthesis

Combinatorial Engineering Enables Photoautotrophic Growth in High Cell Density Phosphite-Buffered Media to Support Engineered Chlamydomonas reinhardtii Bio-Production Concepts

Authors: Malak N Abdallah, Gordon B Wellman, Sebastian Overmans, Kyle J Lauersen

Journal: Frontiers in Microbiology

Doi: 10.3389/fmicb.2022.885840

Products & Services: Plasmid DNA Preparation

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP

Authors: Andrea Pawellek; Ursula Ryder; Triin Tammsalu; Lewis J King; Helmi Kreinin; Tony Ly; Ronald T Hay; Richard C Hartley; Angus I Lamond

Journal: Elife

PubMed ID: 28884683

Doi: 10.7554/eLife.27402

Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug resistant fungi

Authors: Xuefei Chen; H. Diessel Duan; Michael J. Hoy; Kalinka Koteva; Michaela Spitzer; Allison K. Guitor; Emily Puumala; Aline A. Fiebig; Guanggan Hu; Bonnie Yiu; Sommer Chou; Zhuyun Bian; Yeseul Choi; Amelia Bing Ya Guo; Wenliang Wang; Sheng Sun; Nicole Robbins; Anna Floyd Averette; Michael A. Cook; Ray Truant; Lesley T. MacNeil; Eric D. Brown; James W. Kronstad; Brian K. Coombes; Leah E. Cowen; Joseph Heitman; Huilin Li; Gerard D. Wright

Journal: Cell

PubMed ID: 41478284

Doi: 10.1016/j.cell.2025.11.036

Products & Services: Protein and Antibody Isolation

A model for drug transport across two membranes of Gram-negative bacteria by an MFS tripartite assembly

Authors: Zhaojun Zhong; Tuerxunjiang Maimaiti; Matthew L. Jackson; Rui Dong; Xueyan Gao; Qing Ouyang; Wenqian Wang; Jinliang Guo; Shangrong Li; Wenyu Shang; Huajun Liu; Hongnian Jiang; Shuo Zhang; Ulrich Zachariae; Ben F. Luisi; Yanjie Chao; Dijun Du

Journal: Nature Communications

PubMed ID: 41839863

Doi: 10.1038/s41467-026-70500-5

Products & Services: Protein and Antibody Isolation

Rgs16 promotes antitumor CD8 T cell exhaustion

Authors: Nina Weisshaar, Jingxia Wu, Yanan Ming, Alaa Madi, Agnes Hotz-Wagenblatt, Sicong Ma, Alessa Mieg, Marvin Hering, Ferdinand Zettl, Kerstin Mohr, Tilo Schlimbach, Nora Ten Bosch, Franziska Hertel, Lisann Müller, Hannah Byren, Mona Wang, Helena Borgers, Mareike Munz, Lukas Schmitt, Franciscus van der Hoeven, Ulrich Kloz, Rafael Carretero, Nikolai Schleußner, Rene-Filip Jackstadt, Ilse Hofmann, Guoliang Cui

Journal: Sci Immunol

PubMed ID: 35622904

Doi: 10.1126/sciimmunol.abh1873

Products & Services: Catalog Peptides

Agrobacterium expressing a type III secretion system delivers Pseudomonas effectors into plant cells to enhance transformation

Authors: Vidhyavathi Raman, Clemencia M Rojas, Balaji Vasudevan, Kevin Dunning, Jaydeep Kolape, Sunhee Oh, Jianfei Yun, Lishan Yang, Guangming Li, Bikram D Pant, Qingzhen Jiang, Kirankumar S Mysore

Journal: Nat Commun

PubMed ID: 35546550

Doi: 10.1038/s41467-022-30180-3

Products & Services: Bacterial Expression

The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism

Authors: Haolin Zhang, Xuemei Gong, Qianqian Zhao, Takahito Mukai, Oscar Vargas-Rodriguez, Huiming Zhang, Yuxing Zhang, Paul Wassel, Kazuaki Amikura, Julie Maupin-Furlow, Yan Ren, Xun Xu, Yuri I Wolf, Kira S Makarova, Eugene V Koonin, Yue Shen, Dieter Söll, Xian Fu

Journal: Nucleic Acids Res

PubMed ID: 35466371

Doi: 10.1093/nar/gkac271

Products & Services: Protein and Antibody Isolation