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Enhancing fluxes through the mevalonate pathway in Saccharomyces cerevisiae by engineering the HMGR and β-alanine metabolism

Authors: Surui Lu, Chenyao Zhou, Xuena Guo, Zhengda Du, Yanfei Cheng, Zhaoyue Wang, Xiuping He

Journal: Microb Biotechnol

PubMed ID: 35531990

Doi: 10.1111/1751-7915.14072

Products & Services: Gene Fragments

The key sulfometuron-methyl degrading bacteria isolation based on soil bacterial phylogenetic molecular ecological networks and application for bioremediation of contaminated soil by immobilization

Authors: Hao Zhang, Chun-Yang Liu, Xin Zhang, Hui-Ying Yang, Jie Sun, Cheng-Bin Liu, Na Li

Journal: Ecotoxicol Environ Saf

PubMed ID: 35561546

Doi: 10.1016/j.ecoenv.2022.113605

Products & Services: Protein and Antibody Isolation

Smartly responsive DNA-miRNA hybrids packaged in exosomes for synergistic enhancement of cancer cell apoptosis

Authors: Fan Zhang, Albertina N Isak, Shiqi Yang, Yuchen Song, Lingjie Ren, Chang Feng, Guifang Chen

Journal: Nanoscale

PubMed ID: 35421879

Doi: 10.1039/d1nr08539e

Products & Services: Gene Synthesis

Identification of RBMX as a splicing regulator in Parkinsonian mimetic induced alternative splicing of α-synuclein

Authors: Swaroop Thonda, Ravali L Vinnakota, Swathi V Kona, Shasi V Kalivendi

Journal: Biochim Biophys Acta Gene Regul Mech

PubMed ID: 35577270

Doi: 10.1016/j.bbagrm.2022.194825

Products & Services: Gene Fragments

A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

Authors: Hugo Helbert , Emily M Ploeg , Douwe F Samplonius , Simon N Blok , Ines F Antunes , Verena I Böhmer , Gert Luurtsema , Rudi A J O Dierckx , Ben L Feringa , Philip H Elsinga , Wiktor Szymanski , Wijnand Helfrich

Journal: EJNMMI Radiopharm Chem .

PubMed ID: 35239034

Doi: 10.1186/s41181-022-00155-2

Products & Services: Gene Synthesis

Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD

Authors: Tim Krischuns, Catherine Isel, Petra Drncova, Maria Lukarska, Alexander Pflug, Sylvain Paisant, Vincent Navratil, Stephen Cusack, Nadia Naffakh

Journal: PLoS Pathog

PubMed ID: 35605026

Doi: 10.1371/journal.ppat.1010328

Products & Services: PCR Cloning and Subcloning

Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants

Authors: Yaning Li, Qing Fan, Bing Zhou, Yaping Shen, Yuanyuan Zhang, Lin Cheng, Furong Qi, Shuo Song, Yingying Guo, Renhong Yan, Bin Ju, Zheng Zhang

Journal: iScience

PubMed ID: 35607524

Doi: 10.1016/j.isci.2022.104431

Products & Services: Protein and Antibody Isolation

Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders

Authors: Elif Eroglu, Christopher Y T Yen, Yat-Long Tsoi, Nevin Witman, Ahmed Elewa, Alberto Joven Araus, Heng Wang, Tamara Szattler, Chimezie H Umeano, Jesper Sohlmér, Alexander Goedel, András Simon, Kenneth R Chien

Journal: Nat Cell Biol

PubMed ID: 35550612

Doi: 10.1038/s41556-022-00902-2

Products & Services: Plasmid DNA Preparation

Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2

Authors: Juliana C Ferreira, Samar Fadl, Wael M Rabeh

Journal: J Biol Chem

PubMed ID: 35568197

Doi: 10.1016/j.jbc.2022.102023

Products & Services: Mutant Libraries

Comparative Immunogenicity of Bacterially Expressed Soluble Trimers and Nanoparticle Displayed Influenza Hemagglutinin Stem Immunogens

Authors: Uddipan Kar, Sara Khaleeq, Priyanka Garg, Madhuraj Bhat, Poorvi Reddy, Venkada Subramanian Vignesh, Aditya Upadhyaya, Mili Das, Ghadiyaram Chakshusmathi, Suman Pandey, Somnath Dutta, Raghavan Varadarajan

Journal: Front Immunol

PubMed ID: 35720346

Doi: 10.3389/fimmu.2022.890622

Products & Services: Codon Optimization