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Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring

Authors: Xiangwei Wu, Huasong Ai, Junxiong Mao, Hongyi Cai, Lu-Jun Liang, Zebin Tong, Zhiheng Deng, Qingyun Zheng, Lei Liu, Man Pan

Journal: nature COMMUNICATION

PubMed ID: 40341121

Doi: doi.org/10.1038/s41467-025-59569-6

Products & Services: Gene Synthesis Codon Optimization PCR Cloning and Subcloning Mutagenesis Services

Structure-guided design of endosomolytic chloroquine-like lipid nanoparticles for mRNA delivery and genome editing

Authors: Zhen Liu, Jiacai Wu, Ning Wang, Yongqi Lin, Ruiteng Song, Min Zhang, Bin Li

Journal: Nature Communications

PubMed ID: 40335474

Doi: 10.1038/s41467-025-59501-y

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Tandem ketone reduction in pepstatin biosynthesis reveals an F420H2-dependent statine pathway

Authors: Jingjun Mo, Asfandyar Sikandar, Haowen Zhao, Ghader Bashiri, Liujie Huo, Martin Empting, Rolf Müller, Chengzhang Fu

Journal: Nature Communications

PubMed ID: 40374670

Doi: 10.1038/s41467-025-59785-0

Products & Services: Gene Synthesis

Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease

Authors: Haozhou Tan, Qianru Zhang, Kyriakos Georgiou, Siyu Zhang, Kan Li, George Lambrinidis, Antonios Kolocouris, Xufang Deng, Jun Wang

Journal: Nature Communications

PubMed ID: 40379662

Doi: 10.1038/s41467-025-59922-9

Products & Services: Codon Optimization

RabE1a- and SEC10b-mediated exocytosis and AP2β-mediated endocytosis are involved in the intracellular transport of tobamoviruses

Authors: Hua-Yu Ma, Yu Kong, Chao Geng, Yan-Ping Tian, Jun Jiang, Zhi-Yong Yan, Xiang-Dong Li

Journal: Plant Biotechnology Journal.

PubMed ID: 40408557

Doi: 10.1111/pbi.70138

Products & Services: Protein and Antibody Isolation

Freezing induced incorporation of betaine in lipid nanoparticles enhances mRNA delivery

Authors: Xingdi Cheng, Xia Zheng, Kun Tao, Haonan Huo, Zhang Liu, Xueguang Lu, Jianjun Wang

Journal: Nature Communications

PubMed ID: 40394015

Doi: 10.1038/s41467-025-60040-9

Products & Services: Gene Synthesis

Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes

Authors: Alexandra Teslenko , Beat Fierz

Journal: SCIENCE ADVANCES

PubMed ID: 40397729

Doi: 10.1126/sciadv.adt7013

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Stomata-targeted nanocarriers enhance plant defense against pathogen colonization

Authors: Suppanat Puangpathumanond, Heng Li Chee, Cansu Sevencan, Xin Yang, On Sun Lau, Tedrick Thomas Salim Lew

Journal: Nature Communications

PubMed ID: 40410152

Doi: 10.1038/s41467-025-60112-w

Products & Services: Recombinant Proteins

An Engineered PfAgo with Wide Catalytic Temperature Range and Substrate Spectrum

Authors: Longyu Wang, Xiaochen Xie, Fuyong Huang, Qiang Wei, Tianxin Cai, Na Yu, Shi Chen, Fei Wang, Wanping Chen, Chin-Yu Chen, Chunhua Li, Lixin Ma

Journal: Advanced Science

PubMed ID: 40364725

Doi: 10.1002/advs.202416631

Structure and mechanism of human vesicular polyamine transporter

Authors: Yi Guo, Ge Yang, Haijiao Liu, Jin Chai, Jie Chen, John Shanklin, Qun Liu, Bin Liu, Min Lu

Journal: Nature Communications

PubMed ID: 40319071

Doi: 10.1038/s41467-025-59549-w

Products & Services: Gene Synthesis