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Sequence-specific H, C and N backbone NMR assignments for the N-terminal IgV-like domain (D1) and full extracellular region (D1D2) of PD-L1

Authors: Kayleigh Walker, Lorna C Waters, Geoff Kelly, Frederick W Muskett, Mark D Carr

Journal: Biomol NMR Assign

PubMed ID: 35675028

Doi: 10.1007/s12104-022-10092-5

Products & Services: Codon Optimization

Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses

Authors: Ghizlane Maarifi, Marie-France Martin, Abderezak Zebboudj, Aude Boulay, Pierre Nouaux, Juliette Fernandez, Justine Lagisquet, Dominique Garcin, Raphael Gaudin, Nathalie J Arhel, Sébastien Nisole

Journal: Cell Chem Biol

PubMed ID: 35728599

Doi: 10.1016/j.chembiol.2022.05.009

Products & Services: Recombinant Proteins

An in-library ligation strategy and its application in CRISPR/Cas9 screening of high-order gRNA combinations

Authors: Zhike Lu, Ke Ni, Yingying Wang, Yangfan Zhou, Yini Li, Jianfeng Yan, Qingkai Song, Min Liu, Yujun Xu, Zhenxing Yu, Tiannan Guo and Lijia Ma

Journal: Nucleic Acids Res

PubMed ID: 35670669

Doi: 10.1093/nar/gkac458

Products & Services: Oligo pool

Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

Authors: Xiao-dong Luan, Bin-xian Chen, Wei-juan Shang , Wan-chao Yin , Ye Jin , Lei-ke Zhang , H. Eric Xu and Shu-yang Zhang

Journal: Acta pharmacologica Sinica

Doi: 10.1038/s41401-022-00929-z

Products & Services: Gene Synthesis

Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars

Authors: Chaoyu Tian , Jiangang Yang , Cui Liu , Peng Chen , Tong Zhang , Yan Men , Hongwu Ma , Yuanxia Sun, Yanhe Ma

Journal: Nat Commun

PubMed ID: 35739124

Doi: doi.org/10.1038/s41467-022-31371-8

Products & Services: Gene Synthesis

Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant

Authors: Kirsten E Lyke, Robert L Atmar, Clara Dominguez Islas, Christine M Posavad, Daniel Szydlo, Rahul Paul Chourdhury, Meagan E Deming, Amanda Eaton, Lisa A Jackson, Angela R Branche, Hana M El Sahly, Christina A Rostad, Judith M Martin, Christine Johnston, Richard E Rupp, Mark J Mulligan, Rebecca C Brady, Robert W Frenck, Martín Bäcker, Angelica C Kottkamp, Tara M Babu, Kumaravel Rajakumar, Srilatha Edupuganti, David Dobrzynski, Rhea N Coler, Janet I Archer, Sonja Crandon, Jillian A Zemanek, Elizabeth R Brown, Kathleen M Neuzil, David S Stephens, Diane J Post, Seema U Nayak, Mehul S Suthar, Paul C Roberts, John H Beigel, David C Montefiori

Journal: Cell Rep Med

PubMed ID: 35798000

Doi: 10.1016/j.xcrm.2022.100679

Products & Services: Mutagenesis Services

Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2

Authors: Maria Martinez-Molledo, Emmanuel Nji, Nicolas Reyes

Journal: Nat Struct Mol Biol

PubMed ID: 35710838

Doi: 10.1038/s41594-022-00786-8

Products & Services: PCR Cloning and Subcloning

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

Authors: Juan Luis Pacheco-Garcia, Dmitry S Loginov, Ernesto Anoz-Carbonell, Pavla Vankova, Rogelio Palomino-Morales, Eduardo Salido, Petr Man, Milagros Medina, Athi N Naganathan, Angel L Pey

Journal: Antioxidants (Basel)

PubMed ID: 35740007

Doi: 10.3390/antiox11061110

Products & Services: Custom Vector Construction

Pharmacological Modulation of Melanocortin 1 Receptor Signaling by Mrap Proteins in

Authors: Xiaolu Tai, Yaqun Zhang, Jindong Yao, Xuan Li, Jun Liu, Jiazhen Han, Jianjun Lyu, Gufa Lin, Chao Zhang

Journal: Front Endocrinol (Lausanne)

PubMed ID: 35795143

Doi: 10.3389/fendo.2022.892407

Products & Services: Catalog Peptides

Deletion of COM donor and acceptor domains and the interaction between modules in bacillomycin D produced by

Authors: Ziyan Lv, Wenjie Ma, Ping Zhang, Zhaoxin Lu, Libang Zhou, Fanqiang Meng, Zuwei Wang, Xiaomei Bie

Journal: Synth Syst Biotechnol

PubMed ID: 35782484

Doi: 10.1016/j.synbio.2022.05.007

Products & Services: Plasmid DNA Preparation