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Disease-linked mutations cause exposure of a protein quality control degron

Authors: Caroline Kampmeyer, Sven Larsen-Ledet, Morten Rose Wagnkilde, Mathias Michelsen, Henriette K M Iversen, Sofie V Nielsen, Søren Lindemose, Alberto Caregnato, Tommer Ravid, Amelie Stein, Kaare Teilum, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Structure

PubMed ID: 35700725

Doi: 10.1016/j.str.2022.05.016

Products & Services: Gene Synthesis

Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA

Authors: Elena S Kim, Jun Zhou, Hu Zhang, Alexander Marchetti, Maarten van de Klundert, Dawei Cai, Xiaoyang Yu, Bidisha Mitra, Yuanjie Liu, Mu Wang, Ulrike Protzer, Haitao Guo

Journal: PLoS Pathog

PubMed ID: 35679251

Doi: 10.1371/journal.ppat.1010576

Products & Services: Custom DNA/RNA Oligos

Duplication of horizontally acquired GH5_2 enzymes played a central role in the evolution of longhorned beetles

Authors: Na Ra Shin, Daniel Doucet, Yannick Pauchet

Journal: Mol Biol Evol

PubMed ID: 35763818

Doi: 10.1093/molbev/msac128

Products & Services: Custom Vector Construction

A novel dual-targeting delivery system for specific delivery of CRISPR/Cas9 using hyaluronic acid, chitosan and AS1411

Authors: Zahra Khademi, Mohammad Ramezani, Mona Alibolandi, Mohammad Reza Zirak, Zahra Salmasi, Khalil Abnous, Seyed Mohammad Taghdisi

Journal: Carbohydr Polym

PubMed ID: 35725215

Doi: 10.1016/j.carbpol.2022.119691

Products & Services: Plasmid DNA Preparation

The Cross-Protective Immunity Landscape Among Different SARS-CoV-2 Variant RBDs

Authors: Wenqiang Sun, Lihong He, Huicong Lou, Wenhui Fan, Limin Yang, Gong Cheng, Wenjun Liu, Lei Sun

Journal: Front Immunol

PubMed ID: 35757743

Doi: 10.3389/fimmu.2022.898520

Products & Services: Plasmid DNA Preparation

L and L Improve Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats through Suppression of Oxidative Stress

Authors: Shujun Jiang, Quanyan Cai, Yang Gao, Hui Dong, Yan Zhao, Fan Wu, Xin Ba, Yang Luan, Xin Zou, Lijun Xu, Fuer Lu

Journal: Evid Based Complement Alternat Med

PubMed ID: 35707467

Doi: 10.1155/2022/4187359

Products & Services: Custom DNA/RNA Oligos

Activated Stellate Cell Paracrine HGF Exacerbated Pancreatic Cancer Cell Ferroptosis Resistance

Authors: Qiwei Wu, Lian Song, Yaxin Guo, Sai Liu, Wenyao Wang, Huli Liu, Aihua Gong, Xiang Liao, Haitao Zhu, Dongqing Wang

Journal: Oxid Med Cell Longev

PubMed ID: 35693705

Doi: 10.1155/2022/2985249

Products & Services: Custom DNA/RNA Oligos

Biochemical, structural, and functional studies reveal that MAB_4324c from Mycobacterium abscessus is an active tandem repeat N-acetyltransferase

Authors: Husam M A B Alsarraf, Kien Lam Ung, Matt D Johansen, Juliette Dimon, Vincent Olieric, Laurent Kremer, Mickaël Blaise

Journal: FEBS Lett

PubMed ID: 35470425

Doi: 10.1002/1873-3468.14360

Products & Services: Custom Vector Construction

Pore-Forming Cardiotoxin VVA2 (Volvatoxin A2) Variant I82E/L86K Is an Atypical Duplex-Specific Nuclease

Authors: Jia-Qi Lu, Jia-Wen Shou, Ka-Ching Lo, Yun-Sang Tang, Wei-Wei Shi, Pang-Chui Shaw

Journal: Toxins (Basel)

PubMed ID: 35737053

Doi: 10.3390/toxins14060392

Products & Services: Gene Fragments

Structural mechanism of protein recognition by the FW domain of autophagy receptor Nbr1

Authors: Jianxiu Zhang, Ying-Ying Wang, Zhao-Qian Pan, Yulu Li, Jianhua Sui, Li-Lin Du, Keqiong Ye

Journal: Nat Commun

PubMed ID: 35752625

Doi: 10.1038/s41467-022-31439-5

Products & Services: Peptide Synthesis