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Gene therapy for guanidinoacetate methyltransferase deficiency restores cerebral and myocardial creatine while resolving behavioral abnormalities
Authors: Suhail Khoja, Jenna Lambert, Matthew Nitzahn, Adam Eliav, YuChen Zhang, Mikayla Tamboline, Colleen T Le, Eram Nasser, Yunfeng Li, Puja Patel, Irina Zhuravka, Lindsay M Lueptow, Ilona Tkachyova, Shili Xu, Itzhak Nissim, Andreas Schulze, Gerald S Lipshutz
Journal: Mol Ther Methods Clin Dev
PubMed ID: 35505663
Doi: 10.1016/j.omtm.2022.03.015
Products & Services: Custom Vector Construction   
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules
Authors: Hui Jin, Kazuki Kishida, Noriko Arase, Sumiko Matsuoka, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Ken Yamamoto, Takehiko Sasazuki, Hisashi Arase
Journal: Sci Adv
PubMed ID: 35245125
Doi: 10.1126/sciadv.abj9867
Products & Services: Peptide Synthesis   
Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression
Authors: Yvonne E Smith, Guannan Wang, Ciara L Flynn, Stephen F Madden, Owen MacEneaney, Rodrigo G B Cruz, Cathy E Richards, Hanne Jahns, Marian Brennan, Mattia Cremona, Bryan T Hennessy, Katherine Sheehan, Alexander Casucci, Faizah A Sani, Lance Hudson, Joanna Fay, Sri H Vellanki, Siobhan O'Flaherty, Marc Devocelle, Arnold D K Hill, Kieran Brennan, Saraswati Sukumar, Ann M Hopkins
Journal: Cancers (Basel)
PubMed ID: 35267611
Doi: 10.3390/cancers14051303
Products & Services: Peptide Synthesis   
A Protein vaccine with Alum/c-GAMP/poly(I:C) rapidly boosts robust immunity against SARS-CoV-2 and variants of concern
Authors: Ru-Yan Zhang , Xu-Guang Yin , Shi-Hao Zhou , Hai-Wei Zhang , Jie Lu , Chen-Bin He , Jian Wang , Yu Wen , Yu-Ting Li , Yan-Ling Liu , Ran-Ran Feng , Dong Ding , Hua-Wei Wei , Rui Gong , Guang-Fu Yang , Jun Guo
Journal: Chem Commun
PubMed ID: 35244125
Doi: 10.1039/D2CC00271J
Products & Services: Catalog Peptides   
Development of a p72 trimer-based colloidal gold strip for detection of antibodies against African swine fever virus
Authors: Rui Geng, Yaning Sun, Rui Li, Jifei Yang, Hongfang Ma, Zixuan Qiao, Qingxia Lu, Songlin Qiao, Gaiping Zhang
Journal: Appl Microbiol Biotechnol
PubMed ID: 35291024
Doi: 10.1007/s00253-022-11851-z
Products & Services: Protein and Antibody Isolation   
Baohuoside I Inhibits Tumor Angiogenesis in Multiple Myeloma the Peroxisome Proliferator-Activated Receptor γ/Vascular Endothelial Growth Factor Signaling Pathway
Authors: Ying Chen, Lina Zhang, Xiaoyan Zang, Xuxing Shen, Jianyong Li, Lijuan Chen
Journal: Front Pharmacol
PubMed ID: 35341213
Doi: 10.3389/fphar.2022.822082
Products & Services: Plasmid DNA Preparation   
Development and Validation of a Competitive ELISA Based on Bovine Monoclonal Antibodies for the Detection of Neutralizing Antibodies against Foot-and-Mouth Disease Virus Serotype A
Authors: Yimei Cao, Kun Li, Xiangchuan Xing, Guoqiang Zhu, Yuanfang Fu, Huifang Bao, Xingwen Bai, Pu Sun, Pinghua Li, Jing Zhang, Xueqing Ma, Jian Wang, Zhixun Zhao, Dong Li, Zaixin Liu, Zengjun Lu
Journal: J Clin Microbiol
PubMed ID: 35254106
Doi: 10.1128/jcm.02142-21
Products & Services: Recombinant Proteins   
Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy
Authors: Juan Qin, Jingfeng Zhang, Lianyun Lin, Omid Haji-Ghassemi, Zhi Lin, Kenneth J Woycechowsky, Filip Van Petegem, Yan Zhang, Zhiguang Yuchi
Journal: Elife
PubMed ID: 35297759
Doi: 10.7554/eLife.75346
Products & Services: Mutant Libraries   
Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling
Authors: Maricel Gomez-Soler, Marina P. Gehring, Bernhard C. Lechtenberg,Elmer Zapata-Mercado, Alyssa Ruelos,Mike W. Matsumoto,Kalina Hristova,and Elena B. Pasquale
Journal: iScience
Doi: doi.org/10.1016/j.isci.2022.103870
Products & Services: Peptide Synthesis   
Global profiling of regulatory elements in the histone benzoylation pathway
Authors: Duo Wang , Fuxiang Yan , Ping Wu, Kexue Ge , Muchun Li , Tingting Li , Ying Gao , Chao Peng , Yong Chen
Journal: Nat Commun
PubMed ID: 35296687
Doi: 10.1038/s41467-022-29057-2
Products & Services: Gene Synthesis   
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