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Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy

Authors: Wen Liu, Yi Zou, Kaiming Li, Haiqing Zhong, Longbo Yu, Shushan Ge, Yisheng Lai, Xianchi Dong, Qiang Xu, Wenjie Guo

Journal: J Immunol

PubMed ID: 35725271

Doi: 10.4049/jimmunol.2100938

Products & Services: Mammalian Expression

Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR)

Authors: Johannes C van der Mijn, Qiuying Chen, Kristian B Laursen, Francesca Khani, Xiaofei Wang, Princesca Dorsaint, Andrea Sboner, Steven S Gross, David M Nanus, Lorraine J Gudas

Journal: Mol Carcinog

PubMed ID: 35726553

Doi: 10.1002/mc.23437

Products & Services: Protein and Antibody Isolation

Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection

Authors: Amy R Rappaport, Sue-Jean Hong, Ciaran D Scallan, Leonid Gitlin, Arvin Akoopie, Gregory R Boucher, Milana Egorova, J Aaron Espinosa, Mario Fidanza, Melissa A Kachura, Annie Shen, Gloria Sivko, Anne Van Abbema, Robert L Veres, Karin Jooss

Journal: Nat Commun

PubMed ID: 35672369

Doi: 10.1038/s41467-022-31005-z

Products & Services: Catalog Peptides

Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma

Authors: Victor O Oria, Hongyi Zhang, Christopher R Zito, Chetan K Rane, Xian-Yong Ma, Olivia K Provance, Thuy T Tran, Adebowale Adeniran, Yuval Kluger, Mario Sznol, Marcus W Bosenberg, Harriet M Kluger, Lucia B Jilaveanu

Journal: Cell Mol Life Sci

PubMed ID: 35737114

Doi: 10.1007/s00018-022-04364-5

Products & Services: Gene Synthesis

Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186

Authors: Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Ying Zhu, Maia Vinogradova, Robert B DuBridge, Chad May

Journal: J Immunother Cancer

PubMed ID: 35728872

Doi: 10.1136/jitc-2021-004336

Products & Services: Protein and Antibody Isolation

Molecular insights into intra-complex signal transmission during stressosome activation

Authors: Algirdas Miksys, Lifei Fu, M Gregor Madej, Duarte N Guerreiro, Susann Kaltwasser, Maria Conway, Sema Ejder, Astrid Bruckmann, Jon Marles-Wright, Richard J Lewis, Conor O'Byrne, Jan Pané-Farré, Christine Ziegler

Journal: Commun Biol

PubMed ID: 35760945

Doi: 10.1038/s42003-022-03549-9

Products & Services: Protein and Antibody Isolation

SpyChIP identifies cell type-specific transcription factor occupancy from complex tissues

Authors: Siqian Feng, Richard S Mann

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35696584

Doi: 10.1073/pnas.2122900119

Products & Services: Peptide Synthesis

GLYCINE-RICH RNA-BINDING PROTEIN 7 potentiates effector-triggered immunity through an RNA recognition motif

Authors: Octavina C A Sukarta, Qi Zheng, Erik J Slootweg, Mark Mekken, Melanie Mendel, Vera Putker, André Bertran, Anouk Brand, Hein Overmars, Rikus Pomp, Jan Roosien, Sjef Boeren, Geert Smant, Aska Goverse

Journal: Plant Physiol

PubMed ID: 35218353

Doi: 10.1093/plphys/kiac081

Products & Services: Gene Synthesis

A prion-like domain of TFEB mediates the co-aggregation of TFEB and mHTT

Authors: Junsheng Yang, Huilin Xu, Chaoyue Zhang, Xiaotong Yang, Weijie Cai, Xiaoli Chen

Journal: Autophagy

PubMed ID: 35635192

Doi: 10.1080/15548627.2022.2083857

Products & Services: Protein and Antibody Isolation

Asexual Blood-Stage Malaria Vaccine Candidate PfRipr5: Enhanced Production in Insect Cells

Authors: Ricardo Correia, Bárbara Fernandes, Rute Castro, Hikaru Nagaoka, Eizo Takashima, Takafumi Tsuboi, Akihisa Fukushima, Nicola K Viebig, Hilde Depraetere, Paula M Alves, António Roldão

Journal: Front Bioeng Biotechnol

PubMed ID: 35845392

Doi: 10.3389/fbioe.2022.908509

Products & Services: Insect Expression