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页码: 697/5368 每页显示数量

Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents

Authors: Jiyun Zhu, Linfeng Li, Aleksandra Drelich, Bala C Chenna, Drake M Mellott, Zane W Taylor, Vivian Tat, Christopher Z Garcia, Ardala Katzfuss, Chien-Te K Tseng, Thomas D Meek

Journal: Front Chem

PubMed ID: 35860632

Doi: 10.3389/fchem.2022.867928

Products & Services: Gene Synthesis

HJM-561, a Potent, Selective, and Orally Bioavailable EGFR PROTAC that Overcomes Osimertinib-Resistant EGFR Triple Mutations

Authors: Yong Du, Yongfeng Chen, Yuxia Wang, Jinju Chen, Xiaorong Lu, Li Zhang, Yan Li, Zhaofu Wang, Guozhong Ye, George Zhang

Journal: Mol Cancer Ther

PubMed ID: 35499406

Doi: 10.1158/1535-7163.MCT-21-0835

Products & Services: Protein and Antibody Isolation

Analysis of FR901379 Biosynthetic Genes in by Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Based Genomic Manipulation

Authors: Teng-Yun Wei, Yan Zheng, Miyang Wan, Songbai Yang, Jiawei Tang, Yuanjie Wu, Jiyang Li, Shao-Xin Chen

Journal: ACS Chem Biol

PubMed ID: 35822391

Doi: 10.1021/acschembio.2c00250

Products & Services: Gene Fragments

Interaction of Liberibacter Solanacearum with Host Psyllid Vitellogenin and Its Association with Autophagy

Authors: Poulami Sarkar, Murad Ghanim

Journal: Microbiol Spectr

PubMed ID: 35863005

Doi: 10.1128/spectrum.01577-22

Products & Services: Protein and Antibody Isolation

Ligand-induced transmembrane conformational coupling in monomeric EGFR

Authors: Shwetha Srinivasan, Raju Regmi, Xingcheng Lin, Courtney A Dreyer, Xuyan Chen, Steven D Quinn, Wei He, Matthew A Coleman, Kermit L Carraway, Bin Zhang, Gabriela S Schlau-Cohen

Journal: Nat Commun

PubMed ID: 35794108

Doi: 10.1038/s41467-022-31299-z

Products & Services: Mutagenesis Services

Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain

Authors: Gamma Chi , Qiansheng Liang , Akshay Sridhar , John B Cowgill , Kasim Sader , Mazdak Radjainia , Pu Qian , Pablo Castro-Hartmann , Shayla Venkaya , Nanki Kaur Singh , Gavin McKinley , Alejandra Fernandez-Cid , Shubhashish M M Mukhopadhyay , Nicola A Burgess-Brown , Lucie Delemotte , Manuel Covarrubias , Katharina L Dürr

Journal: Nat Commun

PubMed ID: 35840580

Doi: 10.1038/s41467-022-29594-w

Products & Services: Plasmid DNA Preparation

Induction of Broadly Cross-Reactive Antibody Responses to SARS-CoV-2 Variants by S1 Nanoparticle Vaccines

Authors: Cong Sun , Run-Yu Yuan , Chu Xie , Jiu-Feng Sun , Xin-Yan Fang , Yi-Sha Hu , Xiao-Hui Yu, Zheng Liu , Mu-Sheng Zeng , Yin-Feng Kang

Journal: J Virol

PubMed ID: 35699445

Doi: 10.1128/jvi.00383-22

Products & Services: Gene Synthesis Endotoxin Detection & Removal System

Immunogenicity of the third and fourth BNT162b2 mRNA COVID-19 boosters and factors associated with immune response in patients with SLE and rheumatoid arthritis

Authors: Theerada Assawasaksakul, Seelwan Sathitratanacheewin, Preeyaporn Vichaiwattana, Nasamon Wanlapakorn, Yong Poovorawan, Yingyos Avihingsanon, Nawaporn Assawasaksakul, Wonngarm Kittanamongkolchai

Journal: Lupus Sci Med

PubMed ID: 35902168

Doi: 10.1136/lupus-2022-000726

HOXB5-activated ANGPT2 promotes the proliferation, migration, invasion and angiogenic effect of esophageal cancer cells via activating ERK/AKT signaling pathway

Authors: Jing Li, Shanshan Gao

Journal: Exp Ther Med

PubMed ID: 35949323

Doi: 10.3892/etm.2022.11522

Products & Services: Gene Synthesis

Large-scale application of free energy perturbation calculations for antibody design

Authors: Fangqiang Zhu, Feliza A Bourguet, William F D Bennett, Edmond Y Lau, Kathryn T Arrildt, Brent W Segelke, Adam T Zemla, Thomas A Desautels, Daniel M Faissol

Journal: Sci Rep

PubMed ID: 35864134

Doi: 10.1038/s41598-022-14443-z

Products & Services: Catalog Antibodies