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Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

Authors: Chao Wang, Li Fan, Rabia R Khawaja, Bangyan Liu, Lihong Zhan, Lay Kodama, Marcus Chin, Yaqiao Li, David Le, Yungui Zhou, Carlo Condello, Lea T Grinberg, William W Seeley, Bruce L Miller, Sue-Ann Mok, Jason E Gestwicki, Ana Maria Cuervo, Wenjie Luo, Li Gan

Journal: Nat Commun

PubMed ID: 35413950

Doi: 10.1038/s41467-022-29552-6

Products & Services: Endotoxin Detection & Removal System

Structural insights into the peptide selectivity and activation of human neuromedin U receptors

Authors: Chongzhao You , Yumu Zhang , Peiyu Xu , Sijie Huang , Wanchao Yin, H Eric Xu , Yi Jiang

Journal: Nat Commun

PubMed ID: 35440625

Doi: 10.1038/s41467-022-29683-w

Products & Services: Peptide Synthesis

Family 1 Glycosyltransferase UGT706F8 from Selectively Catalyzes the Synthesis of Silibinin 7--β-d-Glucoside

Authors: Gonzalo N Bidart, Natalia Putkaradze, Folmer Fredslund, Christian Kjeldsen, Ander Garralda Ruiz, Jens Ø Duus, David Teze, Ditte H Welner

Journal: ACS Sustain Chem Eng

PubMed ID: 35493695

Doi: 10.1021/acssuschemeng.1c07593

Products & Services: Bacterial Expression

Novel insight into the transformation of peptides and potential benefits in brown fermented goat milk by mesoporous magnetic dispersive solid phase extraction-based peptidomics

Authors: Wei Jia, An Du, Zibian Fan, Lin Shi

Journal: Food Chem

PubMed ID: 35504074

Doi: 10.1016/j.foodchem.2022.133110

Products & Services: Protein and Antibody Isolation

Dynamics of Neutralizing Antibody and T-Cell Responses to SARS-CoV-2 and Variants of Concern after Primary Immunization with CoronaVac and Booster with BNT162b2 or ChAdOx1 in Health Care Workers

Authors: Watsamon Jantarabenjakul, Pimpayao Sodsai, Napaporn Chantasrisawad, Anusara Jitsatja, Sasiprapa Ninwattana, Nattakarn Thippamom, Vichaya Ruenjaiman, Chee Wah Tan, Rakchanok Pradit, Jiratchaya Sophonphan, Supaporn Wacharapluesadee, Lin-Fa Wang, Thanyawee Puthanakit, Nattiya Hirankarn, Opass Putcharoen

Journal: Vaccines (Basel)

PubMed ID: 35632395

Doi: 10.3390/vaccines10050639

Products & Services: Recombinant Proteins

Neutralizing antibody responses 300 days after SARS-CoV-2 infection and induction of high antibody titers after vaccination

Authors: Doris Urlaub, Natalie Wolfsdorff, Jan-Erik Hoffmann, Stefanie Dorok, Markus Hoffmann, Moritz Anft, Naomi Pieris, Patrick Günther, Bernhard Schaaf, Uwe Cassens, Peter Bröde, Maren Claus, Lea K Picard, Sabine Wingert, Simone Backes, Deniz Durak, Nina Babel, Stefan Pöhlmann, Frank Renken, Stefan Raunser, Carsten Watzl

Journal: Eur J Immunol

PubMed ID: 35247269

Doi: 10.1002/eji.202149758

Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2

Authors: Natalie Hofmann, Marica Grossegesse, Markus Neumann, Lars Schaade, Andreas Nitsche

Journal: Sci Rep

PubMed ID: 35241780

Doi: 10.1038/s41598-022-07597-3

Products & Services: Recombinant Proteins

Leptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells

Authors: Himanshu Arora, Rehana Qureshi, Kajal Khodamoradi, Deepa Seetharam, Madhumita Parmar, Derek J Van Booven, Isabelle Catherine Issa, Robert Sackstein, Dolores Lamb, Joshua M Hare, Ranjith Ramasamy

Journal: Cell Death Dis

PubMed ID: 35246515

Doi: 10.1038/s41419-022-04658-3

Products & Services: Gene Synthesis

Selection and Application of ssDNA Aptamers for Fluorescence Biosensing Detection of Malachite Green

Authors: Miaojia Xie, Zanlin Chen, Fengguang Zhao, Ying Lin, Suiping Zheng, Shuangyan Han

Journal: Foods

PubMed ID: 35327224

Doi: 10.3390/foods11060801

Products & Services: Gene Synthesis

Sequence-specific destabilization of azurin by tetramethylguanidinium-dipeptide ionic liquids

Authors: Roshani Patel, Austin K Clark, Gabriella DeStefano, Isabella DeStefano, Hunter Gogoj, Erin Gray, Aashka Y Patel, Joshua T Hauner, Gregory A Caputo, Timothy D Vaden

Journal: Biochem Biophys Rep

PubMed ID: 35280523

Doi: 10.1016/j.bbrep.2022.101242

Products & Services: Bacterial Expression