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Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2

Authors: Jun Lan, Peng Chen, Weiming Liu, Wenlin Ren, Linqi Zhang, Qiang Ding, Qi Zhang, Xinquan Wang, Jiwan Ge

Journal: Structure

PubMed ID: 35917815

Doi: 10.1016/j.str.2022.07.005

Products & Services: Gene Synthesis

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Authors: Brian R Shy, Vivasvan S Vykunta, Alvin Ha, Alexis Talbot, Theodore L Roth, David N Nguyen, Wolfgang G Pfeifer, Yan Yi Chen, Franziska Blaeschke, Eric Shifrut, Shane Vedova, Murad R Mamedov, Jing-Yi Jing Chung, Hong Li, Ruby Yu, David Wu, Jeffrey Wolf, Thomas G Martin, Carlos E Castro, Lumeng Ye, Jonathan H Esensten, Justin Eyquem, Alexander Marson

Journal: Nat Biotechnol

PubMed ID: 36008610

Doi: 10.1038/s41587-022-01418-8

Products & Services: Gene Synthesis

Novel antiinflammatory biologics shaped by parasite-host coevolution

Authors: Stephanie M Ryan, Roland Ruscher, Wayne A Johnston, Darren A Pickering, Malcolm W Kennedy, Brian O Smith, Linda Jones, Geraldine Buitrago, Matt A Field, Adrian J Esterman, Connor P McHugh, Daniel J Browne, Martha M Cooper, Rachael Y M Ryan, Denise L Doolan, Christian R Engwerda, Kim Miles, Makedonka Mitreva, John Croese, Tony Rahman, Kirill Alexandrov, Paul R Giacomin, Alex Loukas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36037362

Doi: 10.1073/pnas.2202795119

Products & Services: Mammalian Expression

[Honokiol reduces doxorubicin-induced cardiotoxicity by inhibiting pyroptosis activating AMPK/Nrf2 signaling]

Authors: F Xiong, R Liu, Y Li, N Sun

Journal: Nan Fang Yi Ke Da Xue Xue Bao

PubMed ID: 36073220

Doi: 10.12122/j.issn.1673-4254.2022.08.13

Products & Services: Catalog Antibodies

Hydrogel Injection Molding to Generate Complex Cell Encapsulation Geometries

Authors: Amy E Emerson, Alec B McCall, Sarah R Brady, Emily M Slaby, Jessica D Weaver

Journal: ACS Biomater Sci Eng

PubMed ID: 36044604

Doi: 10.1021/acsbiomaterials.2c00640

Products & Services: Protein and Antibody Isolation

De Novo Design of an Androgen Receptor DNA Binding Domain Targeted peptide PROTAC for Prostate Cancer Therapy

Authors: Bohan Ma; Yizeng Fan; Dize Zhang; Yi Wei; Yanlin Jian; Donghua Liu; Zixi Wang; Yang Gao; Jian Ma; Yule Chen; Shan Xu; Lei Li

Journal: Advanced Science

PubMed ID: 35971165

Doi: 10.1002/advs.202201859

Products & Services: Plasmid DNA Preparation

Immunoprophylaxis using polypeptide chimera vaccines plus adjuvant system promote Th1 response controlling the spleen parasitism in hamster model of visceral leishmaniasis

Authors: Miriã Rodrigues Gusmão, Thaís Lopes Valentim Di Paschoali Ostolin, Lívia Mendes Carvalho, Ana Flávia Pereira Costa, Gabriel José Lucas Moreira, Jamille Mirelle de Oliveira Cardoso, Rodrigo Dian de Oliveira Aguiar-Soares, Alexandre Barbosa Reis, Rory Cristiane Fortes de Brito, Bruno Mendes Roatt

Journal: Vaccine

PubMed ID: 35963820

Doi: 10.1016/j.vaccine.2022.08.005

Products & Services: Custom Vector Construction

Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation

Authors: Jun-Yi Liu, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Shigeharu Yoshida, Kosuke Ogata, Yasushi Ishihama, Yuzuru Imai, Nobutaka Hattori

Journal: Hum Mol Genet

PubMed ID: 35313349

Doi: 10.1093/hmg/ddac064

Products & Services: Mutagenesis Services

Neuroprotection of Bone Marrow-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicle-Enclosed miR-410 Correlates with HDAC4 Knockdown in Hypoxic-Ischemic Brain Damage

Authors: Mingqi Shen, Rongxiu Zheng, Xuan Kan

Journal: Neurochem Res

PubMed ID: 36028735

Doi: 10.1007/s11064-022-03670-5

Products & Services: Mutant Libraries

Pathway elucidation of bioactive rhamnosylated ginsenosides in Panax ginseng and their de novo high-level production by engineered Saccharomyces cerevisiae

Authors: Chaojing Li, Xing Yan, Zhenzhen Xu, Yan Wang, Xiao Shen, Lei Zhang, Zhihua Zhou, Pingping Wang

Journal: Commun Biol

PubMed ID: 35918414

Doi: 10.1038/s42003-022-03740-y

Products & Services: Codon Optimization