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Structural insights into cationic amino acid transport and viral receptor engagement by CAT1

Authors: Lingyun Xia; Bingqian Lin; Rongfeng Zou; Yanyan Wu; Jiaying Xu; Yan Pan; Yuan Yuan; Shuo Li; Yang Yang; Xuemin Chen

Journal: Nature Communications

PubMed ID: 41408058

Doi: 10.1038/s41467-025-67704-6

Products & Services: Protein and Antibody Isolation

Structural insights into cationic amino acid transport and viral receptor engagement by CAT1

Authors: Lingyun Xia; Bingqian Lin; Rongfeng Zou; Yanyan Wu; Jiaying Xu; Yan Pan; Yuan Yuan; Shuo Li; Yang Yang; Xuemin Chen

Journal: Nature Communications

PubMed ID: 41408058

Doi: 10.1038/s41467-025-67704-6

Products & Services: Protein and Antibody Isolation

A rationally designed 18-amino acid peptide with potential as GLP-1 receptor agonist

Authors: Aditi Singh; Sucharita Shadangi; Soumendra Rana

Journal: Frontiers in pharmacology

PubMed ID: 42244872

Doi: 10.3389/fphar.2026.1789257

A tick saliva serpin, Ixs S17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent

Authors: Thu-Thuy Nguyen; Tae Heung Kim; Emily Bencosme-Cuevas; Jacquie Berry; Alex Samuel Kiarie Gaithuma; Moiz Ashraf Ansari; Tae Kwon Kim; Lucas Tirloni; Zeljko Radulovic; James J. Moresco; John R. Yates; Albert Mulenga

Journal: PLOS Pathogens

PubMed ID: 38394332

Doi: 10.1371/journal.ppat.1012032

Products & Services: Monoclonal Antibody Services

Structure-based lead optimization of enterovirus D68 2A protease inhibitors

Authors: Bin Tan; Chang Liu; Kan Li; Prakash Jadhav; George Lambrinidis; Lan Zhu; Linda Olson; Haozhou Tan; Yu Wen; Antonios Kolocouris; Wei Liu; Jun Wang

Journal: Journal of Medicinal Chemistry

PubMed ID: 37857371

Doi: 10.1021/acs.jmedchem.3c00995

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

Authors: Songnan Wang, Randolph M Johnson, Jacqueline A Carozza, Daniel Fernandez, Jan Scicinski, Neil A Verity, Rachel Mardjuki, Xujun Cao, Yingjie Guo, Jacqueline Papkoff, Nigel Ray, Lingyin Li

Journal: Cell reports. Medicine

PubMed ID: 40914167

Doi: 10.1016/j.xcrm.2025.102336

Products & Services: Custom Vector Construction

SMAD3 and p300 complex scaffolding by long non-coding RNA LIMD1-AS1 promotes TGF-β-induced breast cancer cell plasticity

Authors: Chuannan Fan， Davy Cats， Miriam Selle， Olga Khorosjutina， Soniya Dhanjal， Bernhard Schmierer， Hailiang Mei， Peter Ten Dijke， Qian Wang

Journal: Nucleic Acids Research

PubMed ID: 40889156

Doi: 10.1093/nar/gkaf841

Products & Services: CRISPR Services

Translesion DNA polymerases Rev1 and PolH promote LTR-retrotransposon transcription by safeguarding Pol II occupancy in both germline and somatic tissues of Drosophila

Authors: Chongyang Li, Zhe Meng, Qiuju Wen, Wenjuan Yang, Yaqian Xu, Yuening Lyu, Yile Guo, Tong Lyu, Dan Shen, Kun Dou

Journal: Nucleic Acids Research

PubMed ID: 40966519

Doi: 10.1093/nar/gkaf903

OLD amputates the anticodon arm of tRNAs during P2–Lambda interference

Authors: Apurva A Govande, Brian D Matibag, Irem Ünlü, Eric J Wolf, Molly R Sargen, Brooke Ramsey, Sangjin Kim, Sophie Helaine, Ivan R Corrêa Jr, Hoong Chuin Lim

Journal: Nucleic Acids Research

PubMed ID: 40966496

Doi: 10.1093/nar/gkaf874

Products & Services: Gene Services

A NanoLock-enabled, Craspase-based strategy for highly sensitive RNA detection

Authors: Yumeng Xiao, Junyu Chen, Xincan Hou, Hongwei Wang, Kundi Zhang, Sujuan Xu, Tao Jiang, Yangao Huo, Fengyu Zhang, Lichuan Gu

Journal: Nucleic Acids Research

PubMed ID: 40966498

Doi: 10.1093/nar/gkaf907

Products & Services: Gene Services