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Noncanonical roles of chemokine regions in CCR9 activation revealed by structural modeling and mutational mapping

Authors: Inês De Magalhaes Pinheiro, John R D Dawson, Nicolas Calo, Marianne Paolini-Bertrand, Kalyana Bharati Akondi, Gavin Tan, Tracy M Handel, Irina Kufareva, Oliver Hartley

Journal: Nature Communications

PubMed ID: 40825773

Doi: 10.1038/s41467-025-62321-9.

Products & Services: Mutagenesis Services

Insights into type IX secretion from PorKN cogwheel structure bound to PorG and attachment complexes

Authors: Dhana G Gorasia, Eric Hanssen, Manasi Mudaliyar, Craig J Morton, Sepideh Valimehr, Christine Seers, Lianyi Zhang, Matthew T Doyle, Debnath Ghosal, Paul D Veith, Eric C Reynolds

Journal: Nature Communications

PubMed ID: 40830366

Doi: 10.1038/s41467-025-63163-1.

Products & Services: Polyclonal Antibody Services

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Authors: Xin Zhou, Miesje M van der Stoel, Shreyas Kaptan, Haoran Li, Shiqian Li, Maarit Hölttä, Helena Vihinen, Eija Jokitalo, Christoph Thiele, Olli Pietiläinen, Shin Morioka, Junko Sasaki, Takehiko Sasaki, Ilpo Vattulainen, Elina Ikonen

Journal: Nature Communications

PubMed ID: 40841558

Doi: 10.1038/s41467-025-63125-7.

Products & Services: Polyclonal Antibody Services

Vortex-Generated Microdroplets Enable Simple, Rapid, and Low-Volume Measurement of Condensate Volume and Concentration

Authors: Feipeng Chen, Ho Cheung Shum

Journal: Advanced Science

PubMed ID: 40841927

Doi: 10.1002/advs.202511197

Products & Services: Catalog Peptides

4D structural biology-quantitative dynamics in the eukaryotic RNA exosome complex

Authors: Jobst Liebau, Daniela Lazzaretti, Torben Fürtges, Anna Bichler, Michael Pilsl, Till Rudack, Remco Sprangers

Journal: Nature Communications

PubMed ID: 40849410

Doi: 10.1038/s41467-025-62982-6.

Products & Services: Codon Optimization

Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis

Authors: Susovan Sarkar, Hao-Yang Liu, Feng Yuan, Brandon T Malady, Liping Wang, Eileen M Lafer, Jessica Perez, Jon M Huibregtse, Jeanne C Stachowiak

Journal: Nature Communications

PubMed ID: 40854908

Doi: 10.1038/s41467-025-63238-z.

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Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH

Authors: Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr

Journal: Nature Communications

PubMed ID: 40858607

Doi: 10.1038/s41467-025-62819-2.

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Nascent liver proteome reveals enzymes and transcription regulators under physiological and alcohol exposure conditions

Authors: Jiayu Gu, Lihui Lao, Linzhen Hu, Jia Zang, Chao Liu, Ruixi Wan, Ling Tang, Ying Yuan, Yulin Chen, Shixian Lin

Journal: Nature Communications

PubMed ID: 40858584

Doi: 10.1038/s41467-025-63212-9.

Products & Services: Protein and Antibody Isolation

Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education

Authors: Shilpi Agrawal, Abbey L Stokes, Christopher E Nelson

Journal: biorxiv

PubMed ID: 40766677

Doi: 10.1101/2025.07.31.667476

Products & Services: Catalog IVT RNA products

Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

Authors: Javier Moral-Sanz; Isabel Fern ndez-Carrasco; Valentina Ramponi; Amanda Garrido; Izhar Karbat; Pablo Cabezas-Sainz; Esperanza Rivera-de-Torre; Osama Elsallabi; Roberto Mart n-Hern ndez; Jos L. L pez-Aceituno; Nathan L. Price; Laura Sanchez; Gonzalo Colmenarejo; lvaro Mart nez-del-Pozo; Irina Vetter; Angel Cogolludo; Francisco Perez-Vizcaino; Jorge Del-Pozo; Eitan Reuveny; Manuel A. Fern ndez-Rojo; Paul D. Robbins; Rafael de Cabo; Manuel Serrano; Maria P. Ikonomopoulou

Journal: Nature Aging

PubMed ID: 41526742

Doi: 10.1038/s43587-025-01030-w

Products & Services: PCR Cloning and Subcloning