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Disentangling the recognition complexity of a protein hub using a nanopore

Authors: Lauren Ashley Mayse, Ali Imran, Motahareh Ghahari Larimi, Michael S Cosgrove, Aaron James Wolfe, Liviu Movileanu

Journal: Nat Commun

PubMed ID: 35190547

Doi: 10.1038/s41467-022-28465-8

Products & Services: Plasmid DNA Preparation

Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy

Authors: Sheng-Han Kuo, Inmaculada Tasset, Melody M Cheng, Antonio Diaz, Ming-Kai Pan, Ori J Lieberman, Samantha J Hutten, Roy N Alcalay, Sangjun Kim, Pilar Ximénez-Embún, Li Fan, Donghoon Kim, Han Seok Ko, Talene Yacoubian, Ellen Kanter, Ling Liu, Guomei Tang, Javier Muñoz, Sergio Pablo Sardi, Aiqun Li, Li Gan, Ana Maria Cuervo, David Sulzer

Journal: Sci Adv

PubMed ID: 35138901

Doi: 10.1126/sciadv.abm6393

Products & Services: Catalog Peptides

Affibody Modified G-quadruplex DNA Micelles Incorporating Polymeric 5-Fluorodeoxyuridine for Targeted Delivery of Curcumin to Enhance Synergetic Therapy of HER2 Positive Gastric Cancer

Authors: Chao Zhang, Shuangqing Fu, Fanghua Zhang, Mengnan Han, Xuming Wang, Jie Du, Honglei Zhang, Wei Li

Journal: Nanomaterials (Basel)

PubMed ID: 35215023

Doi: 10.3390/nano12040696

Products & Services: Custom DNA/RNA Oligos

KIF18B promotes breast cancer cell proliferation, migration and invasion by targeting TRIP13 and activating the Wnt/β-catenin signaling pathway

Authors: Lan Liu, Zhaofeng Zhang, Xiulin Xia, Jing Lei

Journal: Oncol Lett

PubMed ID: 35251343

Doi: 10.3892/ol.2022.13232

Products & Services: Custom Vector Construction

A CRISPR-based nucleic acid detection method for severe fever with thrombocytopenia syndrome virus

Authors: Yansong Zhang, Xuanyang Bai, Jinhui Li, Jing Xie, Huan Li, Lang Yang, Peihan Li, Peng Li, Hao Dong, Qichao Chen, Xinyan Hu, Yun Wang, Tingting Jiang, Hongbin Song, Leili Jia, Lizhong Li

Journal: Virus Res

PubMed ID: 35143909

Doi: 10.1016/j.virusres.2022.198691

Products & Services: Protein and Antibody Isolation

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

Authors: Guillaume A Petit, Yaoqin Hong, Karrera Y Djoko, Andrew E Whitten, Emily J Furlong, Airlie J McCoy, Jacqueline M Gulbis, Makrina Totsika, Jennifer L Martin, Maria A Halili

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35234148

Doi: 10.1107/S2059798322000729

Products & Services: Bacterial Expression

Human cardiac myosin-binding protein C phosphorylation- and mutation-dependent structural dynamics monitored by time-resolved FRET

Authors: Rhye-Samuel Kanassatega, Thomas A Bunch, Victoria C Lepak, Christopher Wang, Brett A Colson

Journal: J Mol Cell Cardiol

PubMed ID: 35227736

Doi: 10.1016/j.yjmcc.2022.02.005

Products & Services: Gene Fragments

Serum TK1 protein and C-reactive protein correlate to treatment response and predict survival in dogs with hematologic malignancies

Authors: S Saellström, H Sharif, K K Jagarlamudi, H Rönnberg, L Wang, S Eriksson

Journal: Res Vet Sci

PubMed ID: 35245727

Doi: 10.1016/j.rvsc.2022.02.019

Products & Services: Catalog Peptides

Cathepsin B inhibitor alleviates Th1, Th17, and Th22 transcription factor signaling dysregulation in experimental autoimmune encephalomyelitis

Authors: Mushtaq A Ansari, Ahmed Nadeem, Musaad A Alshammari, Sabry M Attia, Saleh A Bakheet, Mohammad R Khan, Thamer H Albekairi, Abdullah F Alasmari, Khaled Alhosaini, Faleh Alqahtani, Haneen A Al-Mazroua, Sheikh F Ahmad

Journal: Exp Neurol

PubMed ID: 35122866

Doi: 10.1016/j.expneurol.2022.113997

Products & Services: Custom DNA/RNA Oligos

Safety and immunogenicity of heterologous and homologous inactivated and adenoviral-vectored COVID-19 vaccine regimens in healthy adults: a prospective cohort study

Authors: Nasamon Wanlapakorn, Nungruthai Suntronwong, Harit Phowatthanasathian, Ritthideach Yorsaeng, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Chompoonut Auphimai, Donchida Srimuan, Thaksaporn Thatsanatorn, Suvichada Assawakosri, Sitthichai Kanokudom, Yong Poovorawan

Journal: Hum Vaccin Immunother

PubMed ID: 35209809

Doi: 10.1080/21645515.2022.2029111