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Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation
Authors: Jun-Yi Liu, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Shigeharu Yoshida, Kosuke Ogata, Yasushi Ishihama, Yuzuru Imai, Nobutaka Hattori
Journal: Hum Mol Genet
PubMed ID: 35313349
Doi: 10.1093/hmg/ddac064
Products & Services: Mutagenesis Services   
Neuroprotection of Bone Marrow-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicle-Enclosed miR-410 Correlates with HDAC4 Knockdown in Hypoxic-Ischemic Brain Damage
Authors: Mingqi Shen, Rongxiu Zheng, Xuan Kan
Journal: Neurochem Res
PubMed ID: 36028735
Doi: 10.1007/s11064-022-03670-5
Products & Services: Mutant Libraries   
Pathway elucidation of bioactive rhamnosylated ginsenosides in Panax ginseng and their de novo high-level production by engineered Saccharomyces cerevisiae
Authors: Chaojing Li, Xing Yan, Zhenzhen Xu, Yan Wang, Xiao Shen, Lei Zhang, Zhihua Zhou, Pingping Wang
Journal: Commun Biol
PubMed ID: 35918414
Doi: 10.1038/s42003-022-03740-y
Products & Services: Codon Optimization   
Identification of the extracellular metallo-endopeptidases ADAM and ADAMTS in the yellow fever mosquito Aedes aegypti
Authors: Christie S Herd, Xiudao Yu, Yingjun Cui, Alexander W E Franz
Journal: Insect Biochem Mol Biol
PubMed ID: 35932972
Doi: 10.1016/j.ibmb.2022.103815
Products & Services: Polyclonal Antibody Services   
Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses
Authors: Norbert Pardi, Juan Manuel Carreño, George O'Dell, Jessica Tan, Csaba Bajusz, Hiromi Muramatsu, Willemijn Rijnink, Shirin Strohmeier, Madhumathi Loganathan, Dominika Bielak, Molly M H Sung, Ying K Tam, Florian Krammer, Meagan McMahon
Journal: Nat Commun
PubMed ID: 35945226
Doi: 10.1038/s41467-022-32149-8
Products & Services: Gene Synthesis   
Identification, molecular and biochemical characterization of a novel thermoactive and thermostable glucoamylase from Thermoanaerobacter ethanolicus
Authors: Natael M Wayllace, Nicolas Hedín, María V Busi, Diego F Gomez-Casati
Journal: Biotechnol Lett
PubMed ID: 35997915
Doi: 10.1007/s10529-022-03296-1
Products & Services: Codon Optimization   
Reduced sister chromatid cohesion acts as a tumor penetrance modifier
Authors: Jun Wang, Holly R Thomas, Yu Chen, Stefanie M Percival, Stephanie C Waldrep, Ryne C Ramaker, Robert G Thompson, Sara J Cooper, Zechen Chong, John M Parant
Journal: PLoS Genet
PubMed ID: 35994499
Doi: 10.1371/journal.pgen.1010341
Products & Services: Gene Synthesis   
Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening
Authors: Danislav S Spassov, Mariyana Atanasova, Irini Doytchinova
Journal: Molecules
PubMed ID: 36080246
Doi: 10.3390/molecules27175478
Products & Services: Catalog Peptides   
An antibody from single human V-rearranging mouse neutralizes all SARS-CoV-2 variants through BA5 by inhibiting membrane fusion
Authors: Sai Luo, Jun Zhang, Alex J B Kreutzberger, Amanda Eaton, Robert J Edwards, Changbin Jing, Hai-Qiang Dai, Gregory D Sempowski, Kenneth Cronin, Robert Parks, Adam Yongxin Ye, Katayoun Mansouri, Maggie Barr, Novalia Pishesha, Aimee Chapdelaine Williams, Lucas Vieira Francisco, Anand Saminathan, Hanqin Peng, Himanshu Batra, Lorenza Bellusci, Surender Khurana, S Munir Alam, David C Montefiori, Kevin O Saunders, Ming Tian, Hidde Ploegh, Tom Kirchhausen, Bing Chen, Barton F Haynes, Frederick W Alt
Journal: Sci Immunol
PubMed ID: 35951767
Doi: 10.1126/sciimmunol.add5446
Products & Services: Monoclonal Antibody Services   Peptide Synthesis   
TCR extracellular domain genetically linked to CD28, 2B4/41BB and DAP10/CD3ζ -engineered NK cells mediates antitumor effects
Authors: Shance Li, Chaoting Zhang, Luyan Shen, Xia Teng, Yefei Xiao, Bentong Yu, Zheming Lu
Journal: Cancer Immunol Immunother
PubMed ID: 35988132
Doi: 10.1007/s00262-022-03275-5
Products & Services: Custom Vector Construction   
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