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Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life

Authors: Torleif Tollefsrud Gjølberg, Rahel Frick, Simone Mester, Stian Foss, Algirdas Grevys, Lene Støkken Høydahl, Øystein Kalsnes Jørstad, Tilman Schlothauer, Inger Sandlie, Morten C Moe, Jan Terje Andersen

Journal: Commun Biol

PubMed ID: 35982144

Doi: 10.1038/s42003-022-03787-x

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Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport

Authors: Adrian Pascal Nievergelt, Ilia Zykov, Dennis Diener, Aditya Chhatre, Tim-Oliver Buchholz, Markus Delling, Stefan Diez, Florian Jug, Luděk Štěpánek, Gaia Pigino

Journal: Curr Biol

PubMed ID: 35926510

Doi: 10.1016/j.cub.2022.07.033

Products & Services: Codon Optimization

ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants

Authors: Neeltje van Doremalen, Jonathan E Schulz, Danielle R Adney, Taylor A Saturday, Robert J Fischer, Claude Kwe Yinda, Nazia Thakur, Joseph Newman, Marta Ulaszewska, Sandra Belij-Rammerstorfer, Greg Saturday, Alexandra J Spencer, Dalan Bailey, Colin A Russell, Sarah C Gilbert, Teresa Lambe, Vincent J Munster

Journal: Nat Commun

PubMed ID: 35941149

Doi: 10.1038/s41467-022-32248-6

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Identification of the Shigella flexneri Wzy Domain Modulating Wzz_pHS-2 Interaction and Detection of the Wzy/Wzz/Oag Complex

Authors: Alice Ascari, Elizabeth Ngoc Hoa Tran, Bart A Eijkelkamp, Renato Morona

Journal: J Bacteriol

PubMed ID: 35980183

Doi: 10.1128/jb.00224-22

Products & Services: Protein and Antibody Isolation

Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains

Authors: Lining Lu, Xiaoguo Zhai, Xiaolong Li, Shuansuo Wang, Lijun Zhang, Luyang Wang, Xi Jin, Lujun Liang, Zhiheng Deng, Zichen Li, Yanfeng Wang, Xiangdong Fu, Honggang Hu, Jiawei Wang, Ziqing Mei, Zhengguo He, Feng Wang

Journal: Nat Commun

PubMed ID: 35945250

Doi: 10.1038/s41467-022-32364-3

Products & Services: Codon Optimization

Dynamicity and persistence of severe acute respiratory syndrome coronavirus-2 antibody response after double dose and the third dose with BBV-152 and AZD1222 vaccines: A prospective, longitudinal cohort study

Authors: Debaprasad Parai, Hari Ram Choudhary, Girish Chandra Dash, Susmita Behera, Narayan Mishra, Dipti Pattnaik, Sunil Kumar Raghav, Sanjeeb Kumar Mishra, Subrat Kumar Sahoo, Aparajita Swain, Ira Mohapatra, Matrujyoti Pattnaik, Aparnamayee Moharana, Sandhya Rani Jena, Ira Praharaj, Subhra Subhadra, Srikanta Kanungo, Debdutta Bhattacharya, Sanghamitra Pati

Journal: Front Microbiol

PubMed ID: 36016787

Doi: 10.3389/fmicb.2022.942659

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Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism

Authors: Carolina Gismene, Jorge Enrique Hernández González, Angela Rocio Niño Santisteban, Andrey Fabricio Ziem Nascimento, Lucas Dos Santos Cunha, Fábio Rogério de Moraes, Cristiano Luis Pinto de Oliveira, Caio C Oliveira, Paola Jocelan Scarin Provazzi, Pedro Geraldo Pascutti, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti

Journal: Int J Mol Sci

PubMed ID: 36077258

Doi: 10.3390/ijms23179857

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Purification of Crimean Congo Hemorrhagic Fever Virus (CCHFV) Nucleocapsid Protein Using Detergent Gradient and Free Thawing

Authors: Austin Royster, Sheema Mir

Journal: Bio Protoc

PubMed ID: 36082370

Doi: 10.21769/BioProtoc.4483

Products & Services: Plasmid DNA Preparation

Tachykinin Neuropeptides and Amyloid β (25-35) Assembly: Friend or Foe?

Authors: Xikun Liu, Pritam Ganguly, Yingying Jin, Michael J Jhatro, Joan-Emma Shea, Steven K Buratto, Michael T Bowers

Journal: J Am Chem Soc

PubMed ID: 35917596

Doi: 10.1021/jacs.2c03845

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Platinum nanoparticles (PtNPs)-based CRISPR/Cas12a platform for detection of nucleic acid and protein in clinical samples

Authors: Jiajie Liang, Peijun Teng, Liangshan Hu, Guanbo He, Qifang Song, Ying Zhang, Bin Peng, Gan Li, Wei Xiao, Donglin Cao, Yong Tang

Journal: Anal Chim Acta

PubMed ID: 36038232

Doi: 10.1016/j.aca.2022.340203

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