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Complementary Roles of Antibody Heavy and Light Chain Somatic Hypermutation in Conferring Breadth and Potency to the HIV-1-Specific CAP256-VRC26 bNAb Lineage
Authors: David Sacks, Kevin Wiehe, Lynn Morris, Penny L Moore
Journal: J Virol
PubMed ID: 35510865
Doi: 10.1128/jvi.00270-22
Products & Services: Catalog Antibodies   
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage
Authors: Xiaoli S Wu, Xue-Yan He, Jonathan J Ipsaro, Yu-Han Huang, Jonathan B Preall, David Ng, Yan Ting Shue, Julien Sage, Mikala Egeblad, Leemor Joshua-Tor, Christopher R Vakoc
Journal: Nature
PubMed ID: 35576971
Doi: 10.1038/s41586-022-04842-7
Products & Services: ORF cDNA Clones/MolecularCloud   
Molecular mechanism of the wake-promoting agent TAK-925
Authors: Jie Yin, Yanyong Kang, Aaron P McGrath, Karen Chapman, Megan Sjodt, Eiji Kimura, Atsutoshi Okabe, Tatsuki Koike, Yuhei Miyanohana, Yuji Shimizu, Rameshu Rallabandi, Peng Lian, Xiaochen Bai, Mack Flinspach, Jef K De Brabander, Daniel M Rosenbaum
Journal: Nat Commun
PubMed ID: 35614071
Doi: 10.1038/s41467-022-30601-3
Products & Services: Protein and Antibody Isolation   
Zika Virus Envelope Protein Domain III Produced in Has the Potential for Diagnostic Applications
Authors: John Willians Oliveira Prates, Mariana Fonseca Xisto, João Vitor da Silva Rodrigues, João Pedro Cruz Colombari, Júlia Maria Alves Meira, Roberto Sousa Dias, Cynthia Canedo da Silva, E Sérgio Oliveira de Paula
Journal: Diagnostics (Basel)
PubMed ID: 35626353
Doi: 10.3390/diagnostics12051198
Products & Services: Recombinant Antibody Expression   
BpEIN31 represses leaf senescence by inhibiting synthesis of ethylene and abscisic acid in Betula platyphylla
Authors: Shiyu Song, Mengyan Ge, Wei Wang, Chenrui Gu, Kun Chen, Qingzhu Zhang, Qibin Yu, Guifeng Liu, Jing Jiang
Journal: Plant Sci
PubMed ID: 35696929
Doi: 10.1016/j.plantsci.2022.111330
Products & Services: Protein Tools   
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen
Authors: Zaid Taha, Rozanne Arulanandam, Glib Maznyi, Elena Godbout, Madalina E Carter-Timofte, Naziia Kurmasheva, Line S Reinert, Andrew Chen, Mathieu J F Crupi, Stephen Boulton, Geneviève Laroche, Alexandra Phan, Reza Rezaei, Nouf Alluqmani, Anna Jirovec, Alexandra Acal, Emily E F Brown, Ragunath Singaravelu, Julia Petryk, Manja Idorn, Kyle G Potts, Hayley Todesco, Cini John, Douglas J Mahoney, Carolina S Ilkow, Patrick Giguère, Tommy Alain, Marceline Côté, Søren R Paludan, David Olagnier, John C Bell, Taha Azad, Jean-Simon Diallo
Journal: Mol Ther
PubMed ID: 35526097
Doi: 10.1016/j.ymthe.2022.04.025
Products & Services: Mammalian Expression   
Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant
Authors: Kanwal Khan, Salman Ali Khan, Khurshid Jalal, Zaheer Ul-Haq, Reaz Uddin
Journal: Virology
PubMed ID: 35576833
Doi: 10.1016/j.virol.2022.05.001
Products & Services: Peptide Synthesis   
BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia
Authors: Ari Sudwarts, Supriya Ramesha, Tianwen Gao, Moorthi Ponnusamy, Shuai Wang, Mitchell Hansen, Alena Kozlova, Sara Bitarafan, Prateek Kumar, David Beaulieu-Abdelahad, Xiaolin Zhang, Lisa Collier, Charles Szekeres, Levi B Wood, Jubao Duan, Gopal Thinakaran, Srikant Rangaraju
Journal: Mol Neurodegener
PubMed ID: 35526014
Doi: 10.1186/s13024-022-00535-x
Products & Services: Plasmid DNA Preparation   
Bioengineered miR-34a modulates mitochondrial inner membrane protein 17 like 2 (MPV17L2) expression toward the control of cancer cell mitochondrial functions
Authors: Wan-Rong Yi, Mei-Juan Tu, Ai-Xi Yu, Jun Lin, Ai-Ming Yu
Journal: Bioengineered
PubMed ID: 35579419
Doi: 10.1080/21655979.2022.2076399
Products & Services: Plasmid DNA Preparation   
De Novo Arginine Synthesis Is Required for Full Virulence of pv During Walnut Bacterial Blight Disease
Authors: Cíntia H D Sagawa, Renata de A B Assis, Paulo A Zaini, Houston Saxe, Phillip A Wilmarth, Michelle Salemi, Brett S Phinney, Abhaya M Dandekar
Journal: Phytopathology
PubMed ID: 34941365
Doi: 10.1094/PHYTO-07-21-0302-R
Products & Services: Mutagenesis Services   
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