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Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment

Authors: Patricia Guerrero-Ochoa, Raquel Ibáñez-Pérez, Germán Berbegal-Pinilla, Diederich Aguilar, Isabel Marzo, Francisco Corzana, Martha Minjárez-Sáenz, Javier Macías-León, Blanca Conde, Javier Raso, Ramón Hurtado-Guerrero, Alberto Anel

Journal: Biomedicines

PubMed ID: 35740244

Doi: 10.3390/biomedicines10061223

Products & Services: Plasmid DNA Preparation

Electrostatics Drive the Molecular Chaperone BiP to Preferentially Bind Oligomerized States of a Client Protein

Authors: Erin E Deans, Judy L M Kotler, Wei-Shao Wei, Timothy O Street

Journal: J Mol Biol

PubMed ID: 35597552

Doi: 10.1016/j.jmb.2022.167638

Products & Services: Catalog Peptides

A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector

Authors: Javier Martínez-García, Manuela Molina, Leticia Odriozola, Angie Molina, Gloria González-Aseguinolaza, Nicholas D Weber, Cristian Smerdou

Journal: Cell Biosci

PubMed ID: 35641984

Doi: 10.1186/s13578-022-00803-9

Products & Services: PCR Cloning and Subcloning

Atypical B cells up-regulate costimulatory molecules during malaria and secrete antibodies with T follicular helper cell support

Authors: Christine S Hopp, Jeff Skinner, Sarah L Anzick, Christopher M Tipton, Mary E Peterson, Shanping Li, Safiatou Doumbo, Kassoum Kayentao, Aissata Ongoiba, Craig Martens, Boubacar Traore, Peter D Crompton

Journal: Sci Immunol

PubMed ID: 35559666

Doi: 10.1126/sciimmunol.abn1250

Products & Services: Recombinant Proteins

Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses

Authors: Brendan Beaton, Sarah C Sasson, Katherine Rankin, Juliette Raedemaeker, Alexander Wong, Priyanka Hastak, Chansavath Phetsouphanh, Andrew Warden, Vera Klemm, C Mee Ling Munier, Alexandra Carey Hoppe, Fiona Tea, Aleha Pillay, Alberto Ospina Stella, Anupriya Aggarwal, Orly Lavee, Ian D Caterson, Stuart Turville, Anthony D Kelleher, Fabienne Brilot, Judith Trotman

Journal: Am J Hematol

PubMed ID: 35607995

Doi: 10.1002/ajh.26619

Products & Services: Catalog Peptides

Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3

Authors: Qing Zhang, Jun Ren, Fangfang Wang, Manman Pan, Long Cui, Mingqian Li, Fan Qu

Journal: Free Radic Biol Med

PubMed ID: 35594990

Doi: 10.1016/j.freeradbiomed.2022.05.010

Products & Services: Protein Electrophoresis and Western

Multiple stem-loop primers induced cascaded loop-mediated isothermal amplification for direct recognition and specific detection of circular RNAs

Authors: Xin Liu, Pengbo Zhang, Kejian Gao, Xiaoyu Wang, Zhengping Li

Journal: Analyst

PubMed ID: 35506753

Doi: 10.1039/d2an00261b

Products & Services: Protein and Antibody Isolation

A Transfected Parasite Line Expressing eGFP Is Able to Complete the Full Life Cycle of the Parasite in Mammalian and Tick Hosts

Authors: Wendell C Johnson, Hala E Hussein, Janaina Capelli-Peixoto, Jacob M Laughery, Naomi S Taus, Carlos E Suarez, Massaro W Ueti

Journal: Pathogens

PubMed ID: 35745477

Doi: 10.3390/pathogens11060623

Products & Services: Plasmid DNA Preparation

Mammalian Display Platform for the Maturation of Bispecific TCR-Based Molecules

Authors: Janine Dilchert, Martin Hofmann, Felix Unverdorben, Roland Kontermann, Sebastian Bunk

Journal: Antibodies (Basel)

PubMed ID: 35645207

Doi: 10.3390/antib11020034

Products & Services: Custom Vector Construction

IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes

Authors: Jose L Garrido, Matías A Medina, Felipe Bravo, Sarah McGee, Francisco Fuentes-Villalobos, Mario Calvo, Yazmin Pinos, James W Bowman, Christopher D Bahl, Maria Ines Barria, Rebecca A Brachman, Raymond A Alvarez

Journal: Cell Rep

PubMed ID: 35617962

Doi: 10.1016/j.celrep.2022.110904

Products & Services: Peptide Synthesis