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SARS-CoV-2 Omicron BA1 and BA2 are attenuated in rhesus macaques as compared to Delta

Authors: Neeltje van Doremalen, Manmeet Singh, Taylor A Saturday, Claude Kwe Yinda, Lizzette Perez-Perez, W Forrest Bohler, Zachary A Weishampel, Matthew Lewis, Jonathan E Schulz, Brandi N Williamson, Kimberly Meade-White, Shane Gallogly, Atsushi Okumura, Friederike Feldmann, Jamie Lovaglio, Patrick W Hanley, Carl Shaia, Heinz Feldmann, Emmie de Wit, Vincent J Munster, Kyle Rosenke

Journal: biorxiv

PubMed ID: 35971544

Doi: 10.1101/2022.08.01.502390

Products & Services: Plasmid DNA Preparation

Dengue Virus NS4b N-Terminus Disordered Region Interacts with NS3 Helicase C-Terminal Subdomain to Enhance Helicase Activity

Authors: Satyamurthy Kundharapu, Tirumala Kumar Chowdary

Journal: Viruses

PubMed ID: 36016333

Doi: 10.3390/v14081712

Products & Services: Custom DNA/RNA Oligos

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Authors: Julia Carnevale, Eric Shifrut, Nupura Kale, William A Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P Bapat, Morgan E Diolaiti, Patrick O'Leary, Shane Vedova, Julia Belk, Bence Daniel, Theodore L Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maelys Born-Bony, Bindu Hegde, Scott Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson

Journal: Nature

PubMed ID: 36002574

Doi: 10.1038/s41586-022-05126-w

Products & Services: ORF cDNA Clones/MolecularCloud

Engineering cell morphology by CRISPR interference in Acinetobacter baylyi ADP1

Authors: Jin Luo, Elena Efimova, Daniel Christoph Volke, Ville Santala, Suvi Santala

Journal: Microb Biotechnol

PubMed ID: 36005297

Doi: 10.1111/1751-7915.14133

Products & Services: Synthetic Guide RNA

CRISPR-Cas9-directed gene tagging using a single integrase-defective lentiviral vector carrying a transposase-based Cas9 off switch

Authors: Emil Aagaard Thomsen, Kristian Alsbjerg Skipper, Sofie Andersen, Didde Haslund, Thomas Wisbech Skov, Jacob Giehm Mikkelsen

Journal: Mol Ther Nucleic Acids

PubMed ID: 36090759

Doi: 10.1016/j.omtn.2022.08.005

Products & Services: Gene Fragments

Expression of ENaC subunits in epithelia

Authors: Gustavo Frindt, Joel R Meyerson, Alexandra Satty, Joseph M Scandura, Lawrence G Palmer

Journal: J Gen Physiol

PubMed ID: 35939271

Doi: 10.1085/jgp.202213124

Products & Services: Custom Vector Construction

Heterologous Expression and Characterization of a Full-length Protozoan Nitroreductase from Leishmania orientalis isolate PCM2

Authors: Panu Pimviriyakul, Yuvarun Kapaothong, Theerapat Tangsupatawat

Journal: Mol Biotechnol

PubMed ID: 36042106

Doi: 10.1007/s12033-022-00556-3

Products & Services: Recombinant Proteins

A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein

Authors: Jiachen Huang, Rose J Miller, Jarrod J Mousa

Journal: Front Immunol

PubMed ID: 36003370

Doi: 10.3389/fimmu.2022.941865

Products & Services: Plasmid DNA Preparation

In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM

Authors: Cheng-Yu Huang, Piotr Draczkowski, Yong-Sheng Wang, Chia-Yu Chang, Yu-Chun Chien, Yun-Han Cheng, Yi-Min Wu, Chun-Hsiung Wang, Yuan-Chih Chang, Yen-Chen Chang, Tzu-Jing Yang, Yu-Xi Tsai, Kay-Hooi Khoo, Hui-Wen Chang, Shang-Te Danny Hsu

Journal: Nat Commun

PubMed ID: 35986008

Doi: 10.1038/s41467-022-32588-3

Products & Services: Codon Optimization

Safety and Humoral and Cellular Immunogenicity of the BNT162b2 SARS-CoV-2 Vaccine in Liver-Transplanted Adolescents Compared to Healthy Adolescents

Authors: Palittiya Sintusek, Supranee Buranapraditkun, Siriporn Khunsri, Varattaya Saengchaisukhonkit, Preeyaporn Vichaiwattana, Donchida Srimuan, Thanunrat Thongmee, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 36016212

Doi: 10.3390/vaccines10081324