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Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide

Authors: Laetitia Coassolo; Niels B. Danneskiold-Sams e; Quennie Nguyen; Amanda Wiggenhorn; Meng Zhao; David Cheng-Hao Wang; David Toomer; Jameel Lone; Yichao Wei; Aayan Patel; Irene Liparulo; Deniz Kavi; Lianna W. Wat; Saranya Chidambaranathan Reghupaty; Julie Jae Kim; Tina Asemi; Ewa Bielczyk-Maczynska; Veronica L. Li; Maria Dolores Moya-Garzon; Nicole A. J. Krentz; Andreas Stahl; Danny Hung-Chieh Chou; Liqun Luo; Katrin J. Svensson

Journal: Nature

PubMed ID: 40044869

Doi: 10.1038/s41586-025-08683-y

An investigation across 45 languages and 12 language families reveals a universal language network

Authors: Saima Malik-Moraleda, Dima Ayyash, Jeanne Gallée, Josef Affourtit, Malte Hoffmann, Zachary Mineroff, Olessia Jouravlev, Evelina Fedorenko

Journal: Nat Neurosci

PubMed ID: 35856094

Doi: 10.1038/s41593-022-01114-5

Products & Services: Process Development Services Anti-idiotype antibody service

The NCF1 variant pR90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells

Authors: Yao Meng, Jianyang Ma, Chao Yao, Zhizhong Ye, Huihua Ding, Can Liu, Jun Li, Guanhua Li, Yuke He, Jia Li, Zhihua Yin, Li Wu, Haibo Zhou, Nan Shen

Journal: J Clin Invest

PubMed ID: 35788118

Doi: 10.1172/JCI153619

Products & Services: Protein and Antibody Isolation

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Authors: Rani Burm, Panagiota Maravelia, Gustaf Ahlen, Sandra Ciesek, Noelia Caro Perez, Anna Pasetto, Stephan Urban, Freya Van Houtte, Lieven Verhoye, Heiner Wedemeyer, Magnus Johansson, Lars Frelin, Matti Sällberg, Philip Meuleman

Journal: Gut

PubMed ID: 35977815

Doi: 10.1136/gutjnl-2022-327216

Products & Services: Protein and Antibody Isolation

mmu-microRNA-92a-3p attenuates pulmonary fibrosis by modulating Cpeb4-mediated Smad2/3 signaling pathway

Authors: Mengkun Shi, Huixia Cui, Jialun Shi, Yunqing Mei

Journal: Funct Integr Genomics

PubMed ID: 35909199

Doi: 10.1007/s10142-022-00879-z

Products & Services: Mutant Libraries

Genome of Uncovers an Extensive Arsenal of Virulence-Related Genes among the Broad-Host-Range Necrotrophic Plant Pathogens

Authors: Paul Daly, Dongmei Zhou, Danyu Shen, Yifan Chen, Taiqiang Xue, Siqiao Chen, Qimeng Zhang, Jinfeng Zhang, Jamie McGowan, Feng Cai, Guan Pang, Nan Wang, Taha Majid Mahmood Sheikh, Sheng Deng, Jingjing Li, Hüseyin Okan Soykam, Irem Kara, David A Fitzpatrick, Irina S Druzhinina, Günseli Bayram Akcapinar, Lihui Wei

Journal: Microbiol Spectr

PubMed ID: 35946960

Doi: 10.1128/spectrum.02268-21

Products & Services: Protein Electrophoresis and Western

Sall4 guides p53-mediated enhancer interference upon DNA damage in mouse embryonic stem cells

Authors: Lei Wang, Xiaojun Tan, Lu Chen, Sisi Xu, Weiping Huang, Nan Chen, Yizhou Wu, Chunyan Wang, Daqiang Zhou, Mangmang Li

Journal: Stem Cells

PubMed ID: 35977539

Doi: 10.1093/stmcls/sxac058

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Rotavirus Spike Protein VP4 Mediates Viroplasm Assembly by Association to Actin Filaments

Authors: Janine Vetter, Guido Papa, Michael Seyffert, Kapila Gunasekera, Giuditta De Lorenzo, Mahesa Wiesendanger, Jean-Louis Reymond, Cornel Fraefel, Oscar R Burrone, Catherine Eichwald

Journal: J Virol

PubMed ID: 35938869

Doi: 10.1128/jvi.01074-22

Products & Services: Gene Fragments

Safety and Immunogenicity of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Subgroup of Healthy Adults in Chile

Authors: Susan M Bueno, Katia Abarca, Pablo A González, Nicolás M S Gálvez, Jorge A Soto, Luisa F Duarte, Bárbara M Schultz, Gaspar A Pacheco, Liliana A González, Yaneisi Vázquez, Mariana Ríos, Felipe Melo-González, Daniela Rivera-Pérez, Carolina Iturriaga, Marcela Urzúa, Angélica Domínguez, Catalina A Andrade, Roslye V Berríos-Rojas, Gisela Canedo-Marroquín, Camila Covián, Daniela Moreno-Tapia, Farides Saavedra, Omar P Vallejos, Paulina Donato, Pilar Espinoza, Daniela Fuentes, Marcela González, Paula Guzmán, Paula Muñoz Venturelli, Carlos M Pérez, Marcela Potin, Álvaro Rojas, Rodrigo A Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Aarón Oyarzún-Arrau, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alessandro Sette, Gang Zeng, Weining Meng, José V González-Aramundiz, Alexis M Kalergis

Journal: Clin Infect Dis

PubMed ID: 34537835

Doi: 10.1093/cid/ciab823

Products & Services: Catalog Antibodies

Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus

Authors: Maya Sangesland, Alba Torrents de la Peña, Seyhan Boyoglu-Barnum, Larance Ronsard, Faez Amokrane Nait Mohamed, Thalia Bracamonte Moreno, Ralston M Barnes, Daniel Rohrer, Nils Lonberg, Musie Ghebremichael, Masaru Kanekiyo, Andrew Ward, Daniel Lingwood

Journal: Immunity

PubMed ID: 35952670

Doi: 10.1016/j.immuni.2022.07.006

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