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BT8009; a Nectin-4 targeting Bicycle® Toxin Conjugate for treatment of solid tumors

Authors: Michael Rigby, Gavin Bennett, Liuhong Chen, Gemma E Mudd, Helen Harrison, Paul J Beswick, Katerine van Rietschoten, Sophie M Watcham, Heather S Scott, Amy N Brown, Peter U Park, Carly Campbell, Eric Haines, Johanna Lahdenranta, Michael J Skynner, Phil Jeffrey, Nicholas Keen, Kevin Lee

Journal: Mol Cancer Ther

PubMed ID: 36112771

Doi: 10.1158/1535-7163.MCT-21-0875

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Förster resonance energy transfer-based kinase mutation phenotyping reveals an aberrant facilitation of Ca/calmodulin-dependent CaMKIIα activity in mutations related to intellectual disability

Authors: Hajime Fujii, Hiroyuki Kidokoro, Yayoi Kondo, Masahiro Kawaguchi, Shin-Ichiro Horigane, Jun Natsume, Sayaka Takemoto-Kimura, Haruhiko Bito

Journal: Front Mol Neurosci

PubMed ID: 36117912

Doi: 10.3389/fnmol.2022.970031

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Small secreted peptides encoded on the wheat ( L) genome and their potential roles in stress responses

Authors: Dongdong Tian, Qi Xie, Zhichao Deng, Jin Xue, Wei Li, Zenglin Zhang, Yifei Dai, Bo Zheng, Tiegang Lu, Ive De Smet, Yongfeng Guo

Journal: Front Plant Sci

PubMed ID: 36212358

Doi: 10.3389/fpls.2022.1000297

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Toll-like receptor 4 signaling pathway mediates both liver and kidney injuries in mice with hepatorenal syndrome

Authors: Mingliang Wang, Tingting Qin, Yunyun Zhang, Ting Zhang, Zirui Zhuang, Yingyu Wang, Yongfang Ding, Yunru Peng

Journal: Am J Physiol Gastrointest Liver Physiol

PubMed ID: 36165507

Doi: 10.1152/ajpgi.00048.2022

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Function identification and characterization of ZRT and IRT-like proteins computationally for nutrition and biofortification in rice

Authors: Khaled Fathy Abdelmotelb Mohammed, Tanushri Kaul, Pawan Kumar Agrawal, Arulprakash Thangaraj, Rashmi Kaul, Sudhir K Sopory

Journal: J Biomol Struct Dyn

PubMed ID: 36111599

Doi: 10.1080/07391102.2022.2118169

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Lymphocyte Subpopulations Associated with Neutralizing Antibody Levels of SARS-CoV-2 for COVID-19 Vaccination

Authors: Wan-Ting Huang, Shao-Wen Weng, Hong-Tai Tzeng, Feng-Chun Yen, Yu-Shao Chiang, Huey-Ling You

Journal: Vaccines (Basel)

PubMed ID: 36146627

Doi: 10.3390/vaccines10091550

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Single-chain insulin analogs threaded by the insulin receptor αCT domain

Authors: Nicholas A Smith, John G Menting, Michael A Weiss, Michael C Lawrence, Brian J Smith

Journal: Biophys J

PubMed ID: 36181268

Doi: 10.1016/j.bpj.2022.09.038

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Oral or intranasal immunization with recombinant Lactobacillus plantarum displaying head domain of Swine Influenza A virus hemagglutinin protects mice from H1N1 virus

Authors: Yufei Zhang, Li Yang, Jiali Zhang, Kun Huang, Xiaomei Sun, Ying Yang, Ting Wang, Qiang Zhang, Zhong Zou, Meilin Jin

Journal: Microb Cell Fact

PubMed ID: 36085207

Doi: 10.1186/s12934-022-01911-4

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Chemoenzymatic Synthesis of SARS-CoV-2 Homogeneous O-Linked Glycopeptides for Exploring Their Inhibition Functions

Authors: Yongheng Rong, Xingyun Wang, Weian Mao, Fang Yuan, Min Chen, Shengjun Wang, Peng George Wang, Zhigang Wu, Yunjiao He, Yun Kong

Journal: ACS Infect Dis

PubMed ID: 36095241

Doi: 10.1021/acsinfecdis.2c00383

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Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C

Authors: Jianli Tang, Sahibzada Waheed Abdullah, Pinghua Li, Jin'en Wu, Chenchen Pei, Suyu Mu, Yunlu Wang, Shiqi Sun, Huichen Guo

Journal: MBio

PubMed ID: 36106732

Doi: 10.1128/mbio.01434-22

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