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Host adaptation of codon usage in SARS-CoV-2 from mammals indicates potential natural selection and viral fitness

Authors: Yanan Fu, Yanping Huang, Jingjing Rao, Feng Zeng, Ruiping Yang, Huabing Tan, Zhixin Liu, Weixing Du, Long Liu

Journal: Arch Virol

PubMed ID: 36166106

Doi: 10.1007/s00705-022-05612-6

Products & Services: Mutagenesis Services

Context-based sensing of orthosomycin antibiotics by the translating ribosome

Authors: Kyle Mangano, James Marks, Dorota Klepacki, Chayan Kumar Saha, Gemma C Atkinson, Nora Vázquez-Laslop, Alexander S Mankin

Journal: Nat Chem Biol

PubMed ID: 36138139

Doi: 10.1038/s41589-022-01138-9

Products & Services: Protein and Antibody Isolation

Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

Authors: James M Cleary, Betty Rouaisnel, Antoine Daina, Srivatsan Raghavan, Lauren A Roller, Brandon M Huffman, Harshabad Singh, Patrick Y Wen, Nabeel Bardeesy, Vincent Zoete, Brian M Wolpin, Julie-Aurore Losman

Journal: NPJ Precis Oncol

PubMed ID: 36056177

Doi: 10.1038/s41698-022-00304-5

Products & Services: Custom Vector Construction

Respiratory Vaccination with Hemagglutinin Nanoliposomes Protects Mice from Homologous and Heterologous Strains of Influenza Virus

Authors: Zachary R Sia, Kevin Chiem, Wei-Chiao Huang, Amal Seffouh, Amir Teimouri Dereshgi, Tara Hogan, Joaquin Ortega, Bruce A Davidson, Luis Martinez-Sobrido, Jonathan F Lovell

Journal: J Virol

PubMed ID: 36106872

Doi: 10.1128/jvi.01006-22

Products & Services: Mutagenesis Services

The Pivotal Mediating Role of AMPK in Liver Tight Junctions and Liver Regeneration of a Partial-Hepatectomy Mouse Model

Authors: Xiaopeng Yan, Qinghua Shu, Liang Zhao, Bowen Sha, Yufeng Zhang

Journal: Transplant Proc

PubMed ID: 36182577

Doi: 10.1016/j.transproceed.2022.08.029

Products & Services: Protein and Antibody Isolation

Antimicrobial Peptide Mechanism Studied by Scattering-Guided Molecular Dynamics Simulation

Authors: Robert Allsopp, Anna Pavlova, Tyler Cline, Aria M Salyapongse, Richard E Gillilan, Y Peter Di, Berthony Deslouches, Jeffery B Klauda, James C Gumbart, Stephanie Tristram-Nagle

Journal: J Phys Chem B

PubMed ID: 36067064

Doi: 10.1021/acs.jpcb.2c03193

Products & Services: Peptide Synthesis

Frequency dependent growth of bacteria in living materials

Authors: Daniel D Lewis, Ting Gong, Yuanwei Xu, Cheemeng Tan

Journal: Front Bioeng Biotechnol

PubMed ID: 36159663

Doi: 10.3389/fbioe.2022.948483

Products & Services: Gene Synthesis

Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay

Authors: Liping Zhou, Tingting Liu, Mengxia Mo, Yulong Shi, Leyun Wu, Yishui Li, Qiuping Qin, Weiliang Zhu, Chengkun Wu, Likun Gong, Zhijian Xu

Journal: J Chem Inf Model

PubMed ID: 36053674

Doi: 10.1021/acs.jcim.2c00881

Products & Services: Protein and Antibody Isolation

A LILRB1 variant with a decreased ability to phosphorylate SHP-1 leads to autoimmune diseases

Authors: Thivaratana Sinthuwiwat, Supranee Buranapraditkun, Wuttichart Kamolvisit, Siraprapa Tongkobpetch, Wanna Chetruengchai, Chalurmpon Srichomthong, Adjima Assawapitaksakul, Chureerat Phokaew, Patipark Kueanjinda, Tanapat Palaga, Tadech Boonpiyathad, Kanya Suphapeetiporn, Nattiya Hirankarn, Vorasuk Shotelersuk

Journal: Sci Rep

PubMed ID: 36104364

Doi: 10.1038/s41598-022-19334-x

Products & Services: Mutagenesis Services

LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin

Authors: Yao Zhou , Danyang Li , Diyin Li , Aizhong Chen , Liuqing He , Jianhua Luo , Liang Tao

Journal: Commun Biol .

PubMed ID: 36064583

Doi: 10.1038/s42003-022-03873-0

Products & Services: Gene Synthesis