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Metabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma

Authors: Akira Nakamizo, Yuichiro Miyamatsu, Haruka Hirose, Toshiyuki Amano, Satoshi Matsuo, Minako Fujiwara, Teppei Shimamura, Koji Yoshimoto

Journal: Sci Rep

PubMed ID: 36175487

Doi: 10.1038/s41598-022-20613-w

Products & Services: Catalog Peptides

Translation inhibition efficacy does not determine the Plasmodium berghei liver stage antiplasmodial efficacy of protein synthesis inhibitors

Authors: James L. McLellan; Kirsten K. Hanson

Journal: biorxiv

PubMed ID: 38106175

Doi: 10.1101/2023.12.07.570699

Translation inhibition efficacy does not determine the Plasmodium berghei liver stage antiplasmodial efficacy of protein synthesis inhibitors

Authors: James L. McLellan; Kirsten K. Hanson

Journal: biorxiv

PubMed ID: 38106175

Doi: 10.1101/2023.12.07.570699

Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

Authors: Callum Beach; David MacLean; Dominika Majorova; Stavros Melemenidis; Dhanya K. Nambiar; Ryan K. Kim; Gabriel N. Valbuena; Silvia Guglietta; Carsten Krieg; Mahnaz Darvish-Damavandi; Tatsuya Suwa; Alistair Easton; Lily V.S. Hillson; Ashley K. McCulloch; Ross K. McMahon; Kathryn Pennel; Joanne Edwards; Sean M. O Cathail; Campbell S. Roxburgh; Enric Domingo; Eui Jung Moon; Dadi Jiang; Yanyan Jiang; Qingyang Zhang; Albert C. Koong; Trent M. Woodruff; Edward E. Graves; Tim Maughan; Simon J.A. Buczacki; Manuel Stucki; Quynh-Thu Le; Simon J. Leedham; Amato J. Giaccia; Monica M. Olcina

Journal: The Journal of clinical investigation

PubMed ID: 37824211

Doi: 10.1172/JCI168277

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Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide

Authors: Laetitia Coassolo; Niels B. Danneskiold-Sams e; Quennie Nguyen; Amanda Wiggenhorn; Meng Zhao; David Cheng-Hao Wang; David Toomer; Jameel Lone; Yichao Wei; Aayan Patel; Irene Liparulo; Deniz Kavi; Lianna W. Wat; Saranya Chidambaranathan Reghupaty; Julie Jae Kim; Tina Asemi; Ewa Bielczyk-Maczynska; Veronica L. Li; Maria Dolores Moya-Garzon; Nicole A. J. Krentz; Andreas Stahl; Danny Hung-Chieh Chou; Liqun Luo; Katrin J. Svensson

Journal: Nature

PubMed ID: 40044869

Doi: 10.1038/s41586-025-08683-y

Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma

Authors: Dexter Kai Hao Thng, Tan Boon Toh, Paolo Pigini, Lissa Hooi, Yock Young Dan, Pierce Kah-Hoe Chow, Glenn Kunnath Bonney, Masturah Bte Mohd Abdul Rashid, Ernesto Guccione, Dave Keng Boon Wee, Edward Kai-Hua Chow

Journal: Bioeng Transl Med

PubMed ID: 36684069

Doi: 10.1002/btm2.10363

Products & Services: Protein and Antibody Isolation

OsAMT1;1 and OsAMT1;2 Coordinate Root Morphological and Physiological Responses to Ammonium for Efficient Nitrogen Foraging in Rice

Authors: Xiangyu Wu, Xiaoxiao Xie, Shan Yang, Qianyu Yin, Huairong Cao, Xiaonan Dong, Jing Hui, Zhi Liu, Zhongtao Jia, Chuanzao Mao, Lixing Yuan

Journal: Plant&cell physiology

PubMed ID: 35861152

Doi: 10.1093/pcp/pcac104

Products & Services: Antibody Modification and Purification Services

Mapping monoclonal anti-SARS-CoV-2 antibody repertoires against diverse coronavirus antigens

Authors: Matheus Oliveira de Souza, Bharat Madan, I-Ting Teng, Aric Huang, Lihong Liu, Ahmed S Fahad, Sheila N Lopez Acevedo, Xiaoli Pan, Mallika Sastry, Matias Gutierrez-Gonzalez, Michael T Yin, Tongqing Zhou, David D Ho, Peter D Kwong, Brandon J DeKosky

Journal: Front Immunol

PubMed ID: 36119018

Doi: 10.3389/fimmu.2022.977064

Products & Services: Protein and Antibody Isolation

Vaccine target and carrier molecule nontypeable Haemophilus influenzae protein D dimerizes like the close Escherichia coli GlpQ homolog but unlike other known homolog dimers

Authors: Seth P Jones, Kali H Cook, Melody L Holmquist, Liam J Almekinder, Annie M Delaney, Ryhl Charles, Natalie Labbe, Janai Perdue, Niaya Jackson, Michael E Pichichero, Ravinder Kaur, Lea V Michel, Michael L Gleghorn

Journal: Proteins

PubMed ID: 36065600

Doi: 10.1002/prot.26418

Products & Services: Protein and Antibody Isolation

Peptide-Based HDL as an Effective Delivery System for Lipophilic Drugs to Restrain Atherosclerosis Development

Authors: Junwei Gao, Ziyun Li, Jing Li, Ping Song, Jinsheng Yang, Wei Xiao, Ning Li, Ruodan Xu

Journal: Int J Nanomedicine

PubMed ID: 36097444

Doi: 10.2147/IJN.S374736

Products & Services: Gene Synthesis