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Unusual (2R,6R)-bicyclo[3.1.1]heptane ring construction in fungal a-trans-bergamotene biosynthesis

Authors: Yan-Hua Wen , Tian-Jiao Chen , Long-Yu Jiang , Li Li , Mengbo Guo , Yu Peng , Jing-Jing Chen , Fei Pei , Jin-Ling Yang , Rui-Shan Wang , Ting Gong , Ping Zhu

Journal: iScience

PubMed ID: 35345459

Doi: 10.1016/j.isci.2022.104030

Products & Services: Gene Synthesis

Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus

Authors: Chathura D Suraweera , Mark G Hinds , Marc Kvansakul

Journal: Viruses

PubMed ID: 35458468

Doi: 10.3390/v14040738

Products & Services: Gene Synthesis

Lactobacillus murinus alleviate intestinal ischemia/reperfusion injury through promoting the release of interleukin-10 from M2 macrophages via Toll-like receptor 2 signaling

Authors: Jingjuan Hu, Fan Deng, Bingcheng Zhao, Zebin Lin, Qishun Sun, Xiao Yang, Mei Wu, Shida Qiu, Yu Chen, Zhengzheng Yan, Sidan Luo, Jin Zhao, Weifeng Liu, Cai Li, Ke Xuan Liu

Journal: Microbiome

PubMed ID: 35241180

Doi: 10.1186/s40168-022-01227-w

Products & Services: Protein and Antibody Isolation

Targeting lipophagy in macrophages improves repair in multiple sclerosis

Authors: Mansour Haidar, Melanie Loix, Sam Vanherle, Tess Dierckx, Tim Vangansewinkel, Pascal Gervois, Esther Wolfs, Ivo Lambrichts, Jeroen F J Bogie, Jerome J A Hendriks

Journal: Autophagy

PubMed ID: 35282773

Doi: 10.1080/15548627.2022.2047343

Products & Services: Endotoxin Detection & Removal System

oligosaccharides increase serotonin in the brain and ameliorate depression promoting 5-hydroxytryptophan production in the gut microbiota

Authors: Zheng-Wei Zhang, Chun-Sheng Gao, Heng Zhang, Jian Yang, Ya-Ping Wang, Li-Bin Pan, Hang Yu, Chi-Yu He, Hai-Bin Luo, Zhen-Xiong Zhao, Xin-Bo Zhou, Yu-Li Wang, Jie Fu, Pei Han, Yu-Hui Dong, Gang Wang, Song Li, Yan Wang, Jian-Dong Jiang, Wu Zhong

Journal: Acta Pharm Sin B

PubMed ID: 35967282

Doi: 10.1016/j.apsb.2022.02.032

Products & Services: PCR Cloning and Subcloning

Genetic ablation of the Bsx homeodomain transcription factor in zebrafish: Impact on mature pineal gland morphology and circadian behavior

Authors: Mikkel Bloss Carstensen, Adar Medvetzky, Alon Weinberger, Wolfgang Driever, Yoav Gothilf, Martin Fredensborg Rath

Journal: J Pineal Res

PubMed ID: 35249239

Doi: 10.1111/jpi.12795

Products & Services: Plasmid DNA Preparation

Two independent cis-acting elements are required for the guard cell-specific expression of SCAP1, which is essential for late stomatal development

Authors: Kosuke Moriwaki, Shuichi Yanagisawa, Koh Iba, Juntaro Negi

Journal: Plant J

PubMed ID: 35061307

Doi: 10.1111/tpj.15679

Products & Services: Gene Fragments

Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators

Authors: Jared P Beyersdorf, Swapnil Bawage, Nahid Iglesias, Hannah E Peck, Ryan A Hobbs, Jay A Wroe, Chiara Zurla, Charles A Gersbach, Philip J Santangelo

Journal: ACS Nano

PubMed ID: 35357116

Doi: 10.1021/acsnano.1c10631

Products & Services: Gene Synthesis

Superior antitumor immunotherapy efficacy of kynureninase modified CAR-T cells through targeting kynurenine metabolism

Authors: Quanjun Yang, Juan Hao, Mengyi Chi, Yaxian Wang, Bo Xin, Jinglu Huang, Jin Lu, Jie Li, Xipeng Sun, Chunyan Li, Yan Huo, Jianping Zhang, Yonglong Han, Cheng Guo

Journal: Oncoimmunology

PubMed ID: 35355679

Doi: 10.1080/2162402X.2022.2055703

Products & Services: Synthetic Guide RNA

Generation of Gal-enhanced bifunctional tumor vaccine

Authors: Jian He, Yu Huo, Zhikun Zhang, Yiqun Luo, Xiuli Liu, Qiaoying Chen, Pan Wu, Wei Shi, Tao Wu, Chao Tang, Huixue Wang, Lan Li, Xiyu Liu, Yong Huang, Yongxiang Zhao, Lu Gan, Bing Wang, Liping Zhong

Journal: Acta Pharm Sin B

PubMed ID: 35865091

Doi: 10.1016/j.apsb.2022.03.002

Products & Services: Custom Vector Construction