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mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts

Authors: Denzil Furtado, Christina Cortez-Jugo, Ya Hui Hung, Ashley I Bush, Frank Caruso

Journal: Mol Pharm

PubMed ID: 36125338

Doi: 10.1021/acs.molpharmaceut.2c00463

Products & Services: Gene Fragments

A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity

Authors: Lian-Sheng Cheng, Yong-Feng Cheng, Wen-Ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang, Guodong Shen

Journal: J Transl Med

PubMed ID: 36076251

Doi: 10.1186/s12967-022-03619-w

Products & Services: Mammalian Expression

Translation inhibition efficacy does not determine the Plasmodium berghei liver stage antiplasmodial efficacy of protein synthesis inhibitors

Authors: James L. McLellan; Kirsten K. Hanson

Journal: biorxiv

PubMed ID: 38106175

Doi: 10.1101/2023.12.07.570699

Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors

Authors: Hisataka Ogawa; Tomoya Ekawa; Yu Mizote; Takashi Akazawa; Hideaki Tahara

Journal: Frontiers in Immunology

PubMed ID: 40666525

Doi: 10.3389/fimmu.2025.1506204

Products & Services: Custom Vector Construction

Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors

Authors: Hisataka Ogawa; Tomoya Ekawa; Yu Mizote; Takashi Akazawa; Hideaki Tahara

Journal: Frontiers in Immunology

PubMed ID: 40666525

Doi: 10.3389/fimmu.2025.1506204

Products & Services: Custom Vector Construction

Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors

Authors: Hisataka Ogawa; Tomoya Ekawa; Yu Mizote; Takashi Akazawa; Hideaki Tahara

Journal: Frontiers in Immunology

PubMed ID: 40666525

Doi: 10.3389/fimmu.2025.1506204

Products & Services: Custom Vector Construction

Viruses inhibit TIR gcADPR signaling to overcome bacterial defense

Authors: Azita Leavitt, Erez Yirmiya, Gil Amitai, Allen Lu, Jeremy Garb, Ehud Herbst, Benjamin R Morehouse, Samuel J Hobbs, Sadie P Antine, Zhen-Yu J Sun, Philip J Kranzusch, Rotem Sorek

Journal: Nature

PubMed ID: 36174646

Doi: 10.1038/s41586-022-05375-9

Products & Services: Custom Vector Construction

Glycosyltransferase engineering and multi-glycosylation routes development facilitating synthesis of high-intensity sweetener mogrosides

Authors: Jiao Li, Shicheng Mu, Jiangang Yang, Cui Liu, Yanfei Zhang, Peng Chen, Yan Zeng, Yueming Zhu, Yuanxia Sun

Journal: iScience

PubMed ID: 36248741

Doi: 10.1016/j.isci.2022.105222

Products & Services: Mutant Libraries

Evaluating Primary Endpoints for COVID-19 Therapeutic Trials to Assess Recovery

Authors: David J Douin, Lianne Siegel, Greg Grandits, Andrew Phillips, Neil R Aggarwal, Jason Baker, Samuel M Brown, Christina C Chang, Anna L Goodman, Birgit Grund, Elizabeth S Higgs, Catherine L Hough, Daniel D Murray, Roger Paredes, Mahesh Parmar, Sarah Pett, Mark N Polizzotto, Uriel Sandkovsky, Wesley H Self, Barnaby E Young, Abdel G Babiker, Victoria J Davey, Virginia Kan, Annetine C Gelijns, Gail Matthews, B Taylor Thompson, H Clifford Lane, James D Neaton, Jens D Lundgren, Adit A Ginde

Journal: Am J Respir Crit Care Med

PubMed ID: 35580040

Doi: 10.1164/rccm.202112-2836OC

Products & Services: Catalog Antibodies

Impact of hypertension on long-term humoral and cellular response to SARS-CoV-2 infection

Authors: Chang Chu, Anne Schönbrunn, Kristin Klemm, Volker von Baehr, Bernhard K Krämer, Saban Elitok, Berthold Hocher

Journal: Front Immunol

PubMed ID: 36119050

Doi: 10.3389/fimmu.2022.915001