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[C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease

Authors: Tharick A Pascoal, Mira Chamoun, Elad Lax, Hsiao-Ying Wey, Monica Shin, Kok Pin Ng, Min Su Kang, Sulantha Mathotaarachchi, Andrea L Benedet, Joseph Therriault, Firoza Z Lussier, Frederick A Schroeder, Jonathan M DuBois, Baileigh G Hightower, Tonya M Gilbert, Nicole R Zürcher, Changning Wang, Robert Hopewell, Mallar Chakravarty, Melissa Savard, Emilie Thomas, Sara Mohaddes, Sarah Farzin, Alyssa Salaciak, Stephanie Tullo, A Claudio Cuello, Jean-Paul Soucy, Gassan Massarweh, Heungsun Hwang, Eliane Kobayashi, Bradley T Hyman, Bradford C Dickerson, Marie-Christine Guiot, Moshe Szyf, Serge Gauthier, Jacob M Hooker, Pedro Rosa-Neto

Journal: Nat Commun

PubMed ID: 35853847

Doi: 10.1038/s41467-022-30653-5

Products & Services: Protein Electrophoresis and Western

The two-domain elevator-type mechanism of zinc-transporting ZIP proteins

Authors: Anders Wiuf, Jonas Hyld Steffen, Eva Ramos Becares, Christina Grønberg, Dhani Ram Mahato, Søren G F Rasmussen, Magnus Andersson, Tristan Croll, Kamil Gotfryd, Pontus Gourdon

Journal: Sci Adv

PubMed ID: 35857505

Doi: 10.1126/sciadv.abn4331

Products & Services: Mutagenesis Services

Pneumolysin suppresses the initial macrophage pro-inflammatory response to Streptococcus pneumoniae

Authors: Jimstan Periselneris, Carolin T Turner, Giuseppe Ercoli, Gabriella Szylar, Caroline M Weight, Teresa Thurston, Matthew Whelan, Gillian Tomlinson, Mahdad Noursadeghi, Jeremy Brown

Journal: Immunology

PubMed ID: 35835695

Doi: 10.1111/imm.13546

Products & Services: Catalog Peptides

Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance

Authors: Xinlei Zhuang, Zhe Wang, Jiansheng Fan, Xuefei Bai, Yingchun Xu, James J Chou, Tingjun Hou, Shuqing Chen, Liqiang Pan

Journal: Nat Commun

PubMed ID: 35907884

Doi: 10.1038/s41467-022-32159-6

Products & Services: Polyclonal Antibody Services

Cutting Edge: Promoting T Cell Factor 1 T Cell Self-Renewal to Improve Programmed Cell Death Protein 1 Blockade

Authors: Peter H Wang, Robert Washburn, Rohan Maniar, Michael Mu, Olivia Ringham, Radomir Kratchmarov, Brian S Henick, Steven L Reiner

Journal: J Immunol

PubMed ID: 35905999

Doi: 10.4049/jimmunol.2200317

Products & Services: Mammalian Expression

Development of Highly Sensitive Sandwich ELISA for the Early-Phase Diagnosis of Chikungunya Virus Utilizing rE2-E1 Protein

Authors: Mohammad Islamuddin, Abuzer Ali, Wajihul Hasan Khan, Amena Ali, Syed Kazim Hasan, Mohd Abdullah, Kentaro Kato, Malik Zainul Abdin, Shama Parveen

Journal: Infect Drug Resist

PubMed ID: 35924014

Doi: 10.2147/IDR.S347545

Products & Services: Gene Synthesis

Evaluation of residue variability in a conformation-specific context and during evolutionary sequence reconstruction narrows drug resistance selection in Abl1 tyrosine kinase

Authors: Felipe A M Otsuka, Sinisa Bjelic

Journal: Protein Sci

PubMed ID: 35762721

Doi: 10.1002/pro.4354

Products & Services: PCR Cloning and Subcloning

Proteomic Network of Antibiotic-Induced Outer Membrane Vesicles Released by Extensively Drug-Resistant Elizabethkingia anophelis

Authors: Ming-Hsien Chiang, Fang-Ju Chang, Dinesh Kumar Kesavan, Aparna Vasudevan, Huaxi Xu, Kuo-Lun Lan, Shu-Wei Huang, Hung-Sheng Shang, Yi-Ping Chuang, Ya-Sung Yang, Te-Li Chen

Journal: Microbiol Spectr

PubMed ID: 35852325

Doi: 10.1128/spectrum.00262-22

Products & Services: Bacterial Expression

HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics

Authors: Matthew D Surette, Nicholas Waglechner, Kalinka Koteva, Gerard D Wright

Journal: Mol Cell

PubMed ID: 35907401

Doi: 10.1016/j.molcel.2022.06.019

Products & Services: Protein and Antibody Isolation

Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal

Authors: Huiyun Liu, Daniel Heller-Trulli, Claire L Moore

Journal: iScience

PubMed ID: 35992060

Doi: 10.1016/j.isci.2022.104804

Products & Services: Custom Vector Construction