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Neoantigen Identification and Response to Adoptive Cell Transfer in Anti-PD-1 Naïve and Experienced Patients with Metastatic Melanoma

Authors: Shoshana T Levi, Amy R Copeland, Shirley Nah, Jessica S Crystal, Gabriel D Ivey, Almin Lalani, Mohammad Jafferji, Bradley S White, Neilesh B Parikh, Vid Leko, Sri Krishna, Frank Lowery, Todd D Prickett, Jared J Gartner, Li Jia, Yong F Li, Abraham Sachs, Sivasish Sindiri, Welles Robinson, Billel Gasmi, James C Yang, Stephanie L Goff, Steven A Rosenberg, Paul F Robbins

Journal: Clin Cancer Res

PubMed ID: 35247926

Doi: 10.1158/1078-0432.CCR-21-4499

Products & Services: Plasmid DNA Preparation

Non-synergy of PD-1 blockade with T-cell therapy in solid tumors

Authors: John S Davies, Farrah Karimipour, Ling Zhang, Nisha Nagarsheth, Scott Norberg, Carylinda Serna, Julius Strauss, Shinheng Chiou, James L Gulley, Christian S Hinrichs

Journal: J Immunother Cancer

PubMed ID: 35793866

Doi: 10.1136/jitc-2022-004906

Products & Services: Catalog Peptides

An effective strategy for the humanization of antibody fragments under an accelerated timeline

Authors: Isabella Gizzi Jiacomini, Martina Beltramino, Fanny Boursin, João Carlos Minozzo, Juliana Ferreira de Moura, Philippe Billiald, Larissa Magalhães Alvarenga, Nicolas Aubrey

Journal: Int J Biol Macromol

PubMed ID: 35803408

Doi: 10.1016/j.ijbiomac.2022.06.195

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Endothelial PHD2 deficiency induces nitrative stress suppression of caveolin-1 in pulmonary hypertension

Authors: Bin Liu, Yi Peng, Dan Yi, Narsa Machireddy, Daoyin Dong, Karina Ramirez, Jingbo Dai, Rebecca Vanderpool, Maggie M Zhu, Zhiyu Dai, You-Yang Zhao

Journal: Eur Respir J

PubMed ID: 35798360

Doi: 10.1183/13993003.02643-2021

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Low molecular weight fucoidan alleviates cerebrovascular damage by promoting angiogenesis in type 2 diabetes mice

Authors: Zhi Li, Ning Wu, Jing Wang, Yang Yue, Lihua Geng, Quanbin Zhang

Journal: Int J Biol Macromol

PubMed ID: 35841956

Doi: doi.org/10.1016/j.ijbiomac.2022.07.053

Products & Services: Protein Electrophoresis and Western

Structural insight into apelin receptor-G protein stoichiometry

Authors: Yang Yue , Lier Liu , Li-Jie Wu , Yiran Wu , Ling Wang , Fei Li , Junlin Liu , Gye-Won Han , Bo Chen , Xi Lin , Rebecca L Brouillette , Émile Breault , Jean-Michel Longpré , Songting Shi , Hui Lei , Philippe Sarret , Raymond C Stevens , Michael A Hanson , Fei Xu

Journal: Nat Struct Mol Biol

PubMed ID: 35817871

Doi: 10.1038/s41594-022-00797-5

Products & Services: Peptide Synthesis

Grp94 Works Upstream of BiP in Protein Remodeling Under Heat Stress

Authors: Yaa S Amankwah, Preston Collins, Yasmeen Fleifil, Erin Unruh, Kevin J Ruiz Márquez, Katherine Vitou, Andrea N Kravats

Journal: J Mol Biol

PubMed ID: 35905823

Doi: 10.1016/j.jmb.2022.167762

Products & Services: Protein and Antibody Isolation

Proteomic and Phosphoproteomic Analyses Reveal Gibel Carp Responses to Cyprinid Herpesvirus 2 Infection

Authors: Chen Xu, Yiqun Li, Zidong Xiao, Jie Yang, Mingyang Xue, Nan Jiang, Yan Meng, Wenzhi Liu, Yuding Fan, Yong Zhou

Journal: J Proteome Res

PubMed ID: 35792615

Doi: 10.1021/acs.jproteome.2c00253

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[C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease

Authors: Tharick A Pascoal, Mira Chamoun, Elad Lax, Hsiao-Ying Wey, Monica Shin, Kok Pin Ng, Min Su Kang, Sulantha Mathotaarachchi, Andrea L Benedet, Joseph Therriault, Firoza Z Lussier, Frederick A Schroeder, Jonathan M DuBois, Baileigh G Hightower, Tonya M Gilbert, Nicole R Zürcher, Changning Wang, Robert Hopewell, Mallar Chakravarty, Melissa Savard, Emilie Thomas, Sara Mohaddes, Sarah Farzin, Alyssa Salaciak, Stephanie Tullo, A Claudio Cuello, Jean-Paul Soucy, Gassan Massarweh, Heungsun Hwang, Eliane Kobayashi, Bradley T Hyman, Bradford C Dickerson, Marie-Christine Guiot, Moshe Szyf, Serge Gauthier, Jacob M Hooker, Pedro Rosa-Neto

Journal: Nat Commun

PubMed ID: 35853847

Doi: 10.1038/s41467-022-30653-5

Products & Services: Protein Electrophoresis and Western

Genome-wide CRISPR Screening Reveals Pyrimidine Metabolic Reprogramming in 5-FU Chronochemotherapy of Colorectal Cancer

Authors: Ya Niu, Xinyi Fan, Yaping Wang, Jiaxin Lin, Luchun Hua, Xiaobo Li, Ruizhe Qian, Chao Lu

Journal: Front Oncol

PubMed ID: 35903686

Doi: 10.3389/fonc.2022.949715

Products & Services: Recombinant Proteins