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PAM-free hairpin target binding activates trans-cleavage activity of Cas12a

Authors: Xiaolong Li, Zixuan Zhu, Jiani Wu, Changjiang Li, Zhujun Liu, Jinjin Wang, Pu Li, Zhen Zhang, Yongming Huang, Jiaxin Hong, Tongbo Wu

Journal: Nucleic Acids Research

PubMed ID: 40557869

Doi: 10.1093/nar/gkaf596

Products & Services: CRISPR Plasmids

An Antagonism Between Ethylene Signaling and DNA Methylation Orchestrates the Progression of Leaf Senescence in Non-heading Chinese Cabbage

Authors: Dingyu Zhang, Yong Luo, Han Wang, Xiaofeng Li, Liming Miao, Lu Gao, Haibo Hao, Xinman Wang, Benke Kuai, Hongfang Zhu, Guodong Ren

Journal: Advanced Science

PubMed ID: 40549976

Doi: 10.1002/advs.202414954

An Il12 mRNA-LNP adjuvant enhances mRNA vaccine-induced CD8 T cell responses

Authors: Emily A Aunins, Anthony T Phan, Mohamad-Gabriel Alameh, Garima Dwivedi, Elisa Cruz-Morales, David A Christian, Ying Tam, Molly E Bunkofske, Anabel Zabala Peñafiel, Keenan M O'Dea, Maria Merolle, Colleen Furey, Phillip Scott, Robert H Vonderheide, Scott E Hensley, Ross M Kedl, Drew Weissman, Christopher A Hunter

Journal: Science immunology

PubMed ID: 40478935

Doi: 10.1126/sciimmunol.ads1328

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Authors: Ya-Zhen Hu, Ting Wang, Chang-Song Wu, Jie Wang, Xue-Qing Han, Yong-An Zhang, Xu-Jie Zhang

Journal: Advanced Science

Doi: 10.1002/advs.202500388

Products & Services: Endotoxin Detection & Removal System

Sindbis virus is suppressed in the yellow fever mosquito aedes aegypti by Atg6/BECN1 (autophagy-related 6)-mediated activation of autophagy

Authors: Sujit Pujhari, Chan C Heu, Marco Brustolin, Rebecca M Johnson, Donghun Kim, Jason L Rasgon

Journal: Autophagy

PubMed ID: 40574305

Doi: 10.1080/15548627.2025.2523735

Products & Services: Plasmid DNA Preparation

Mechanistic studies of small molecule ligands selective to RNA single G bulges

Authors: Shalakha Hegde, Sana Akhter, Zhichao Tang, Chang Qi, Chenguang Yu, Anna Lewicka, Yu Liu, Kushal Koirala, Mikhail Reibarkh, Kevin P Battaile, Anne Cooper, Scott Lovell, Erik D Holmstrom, Xiao Wang, Joseph A Piccirilli, Qi Gao, Yinglong Miao, Jingxin Wang

Journal: Nucleic Acids Research

PubMed ID: 40557870

Doi: 10.1093/nar/gkaf559

Antimicrobial and Potent Anti- Biofilm Properties of Rationally Designed α- Helix Antimicrobial Peptides

Authors: Motasim Ismael, Khayeli Juliah, Madivoli Edwin

Journal: Journal of Peptide Science

PubMed ID: 40326595

Doi: 10.1002/psc.70027

Products & Services: Peptide Synthesis

Control of seed-to-seedling transition by an upstream open reading frame in ABSCISIC ACID DEFICIENT2

Authors: Zhen Wang , Xiaofan Zhang ， Can Zhou , Xiaofeng Cao

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40478869

Doi: 10.1073/pnas.2502155122

Products & Services: Gene Synthesis

Collective Biosynthesis of Plant Spirooxindole Alkaloids through Enzyme Discovery and Engineering

Authors: Danni Chu, Hongkui Wang, Zhiwen Nie, Kang-Li Li, Jiaqing Cao, Meijing Yang, Qin Yin, Yang Gu, Yindi Jiang

Journal: Journal of the American Chemical Society

PubMed ID: 40504680

Doi: 10.1021/jacs.5c02990

Products & Services: Gene Synthesis

Dectin-1 facilitates lung fungal-mediated pulmonary fibrosis

Authors: Ding Qiu, Shuishen Zhang, Chanyan Huang, Xinying Wang, Jianping Deng, Haiyang Sun, Bingbing Feng, Ying Tan, Kaile Ji, Shaoting Xu, Xiaoqi Ye, Chao Cheng, Shigeru Kakuta, Yoshiyuki Adachi, Yoichiro Iwakura, Shuai Wang, Shaowei Dong, Ce Tang

Journal: Immunity

PubMed ID: 40494347

Doi: 10.1016/j.immuni.2025.05.007

Products & Services: Catalog Antibodies