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Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

Authors: Tilman L B Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J Jacobi, Cornelius M Funk, Florian H Geyer, Jing Li, Ignazio Piseddu, Bruno L Cadilha, Stephan Ledderose, Jennifer Zwilling, Shunya Ohmura, David Anz, Annette Künkele, Frederick Klauschen, Thomas G P Grünewald, Maximilian M L Knott

Journal: Mol Cancer

PubMed ID: 36229873

Doi: 10.1186/s12943-022-01641-6

Products & Services: Recombinant Proteins

An inducible gene from glycoside hydrolase one family of decreases larval survival when feeding on host plant

Authors: Wei Chen, Yuhong Dong, Ling Zheng, Yingfang Lai, Feifei Li, Li Zhou, Beibei Wang, Minsheng You, Weiyi He

Journal: Front Physiol

PubMed ID: 36338470

Doi: 10.3389/fphys.2022.1013092

Products & Services: Recombinant Antibody Expression

Discovery and functional characterization of the oncogenicity and targetability of a novel gene fusion in pediatric angiosarcoma

Authors: Payal Jain, Sudarshan Iyer, Joshua Straka, Lea F Surrey, Jennifer Pogoriler, Harry Han, Tiffany Smith, Christine Busch, Elizabeth Fox, Marilyn Li, Angela J Waanders, Adam Resnick, Monika A Davare

Journal: Cold Spring Harb Mol Case Stud

PubMed ID: 36307212

Doi: 10.1101/mcs.a006222

Products & Services: Plasmid DNA Preparation

Protein kinase C beta relieves autism-like behavior in EN2 knockout mice via upregulation of the FTO/PGC-1α/UCP1 axis

Authors: Xingyu Song, Qibo Hu, Xiaoheng Xu, Wei Pan

Journal: J Biochem Mol Toxicol

PubMed ID: 36239013

Doi: 10.1002/jbt.23236

Products & Services: Molecular Biology Reagents

Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules

Authors: Daniel A. Ciulla; Zihan Xu; John L. Pezzullo; Patricia Dranchak; Chunyu Wang; Jos -Luis Giner; James Inglese; Brian P. Callahan

Journal: Methods in enzymology

PubMed ID: 37245899

Doi: 10.1016/bs.mie.2023.03.001

Products & Services: Protein Electrophoresis and Western

Deciphering the Immunogenicity of Monkeypox Proteins for Designing the Potential mRNA Vaccine

Authors: Mohibullah Shah; Samavia Jaan; Muhammad Shehroz; Asifa Sarfraz; Khamna Asad; Tehreem Ul Wara; Aqal Zaman; Riaz Ullah; Essam A. Ali; Umar Nishan; Suvash Chandra Ojha

Journal: ACS Omega

PubMed ID: 38024731

Doi: 10.1021/acsomega.3c07866

Products & Services: Molecular Biology Tools

TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans

Authors: Desmarini Desmarini, Daniel Truong, Lorna Wilkinson-White, Chandrika Desphande, Mario Torrado, Joel P Mackay, Jacqueline M Matthews, Tania C Sorrell, Sophie Lev, Philip E Thompson, Julianne Teresa Djordjevic

Journal: Biomolecules

PubMed ID: 36291735

Doi: 10.3390/biom12101526

Products & Services: Plasmid DNA Preparation

Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)

Authors: Shi Min Tan, Wei-Guang Seetoh

Journal: Sci Rep

PubMed ID: 36271274

Doi: 10.1038/s41598-022-21678-3

Products & Services: Mammalian Expression

Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins

Authors: Phillip L Davidson, Haobing Guo, Jane S Swart, Abdull J Massri, Allison Edgar, Lingyu Wang, Alejandro Berrio, Hannah R Devens, Demian Koop, Paula Cisternas, He Zhang, Yaolei Zhang, Maria Byrne, Guangyi Fan, Gregory A Wray

Journal: Nat Ecol Evol

PubMed ID: 36266460

Doi: 10.1038/s41559-022-01906-9

Products & Services: PCR Cloning and Subcloning

Structural basis of TRPV3 inhibition by an antagonist

Authors: Junping Fan, Linghan Hu, Zongwei Yue, Daohong Liao, Fusheng Guo, Han Ke, Daohua Jiang, Yong Yang, Xiaoguang Lei

Journal: Nat Chem Biol

PubMed ID: 36302896

Doi: 10.1038/s41589-022-01166-5

Products & Services: Catalog Peptides