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Inhibition of PRMT5 by market drugs as a novel cancer therapeutic avenue

Authors: Lakshmi Prabhu, Matthew Martin, Lan Chen, Özlem Demir, Jiamin Jin, Xiumei Huang, Aishat Motolani, Mengyao Sun, Guanglong Jiang, Harikrishna Nakshatri, Melissa L Fishel, Steven Sun, Ahmad Safa, Rommie E Amaro, Mark R Kelley, Yunlong Liu, Zhong-Yin Zhang, Tao Lu

Journal: Genes Dis

PubMed ID: 37013054

Doi: 10.1016/j.gendis.2022.04.001

Products & Services: Protein and Antibody Isolation

Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements

Authors: Caridad Miró-Pina, Olivia Charmant, Takayuki Kawaguchi, Daniel Holoch, Audrey Michaud, Isadora Cohen, Adeline Humbert, Yan Jaszczyszyn, Guillaume Chevreux, Laurence Del Maestro, Slimane Ait-Si-Ali, Olivier Arnaiz, Raphaël Margueron, Sandra Duharcourt

Journal: Dev Cell

PubMed ID: 35429435

Doi: 10.1016/j.devcel.2022.03.014

Products & Services: Protein and Antibody Isolation

A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models

Authors: Anurupa A Ghosh, Dinesh Kumar Verma, Gabriela Cabrera, Kwadwo Ofori, Karina Hernandez-Quijada, Jae-Kwan Kim, Joo Hee Chung, Michael Moore, Sung Hwan Moon, Jong Bok Seo, Yong-Hwan Kim

Journal: Int J Mol Sci

PubMed ID: 35457082

Doi: 10.3390/ijms23084262

Products & Services: Protein Electrophoresis and Western

Bioactive Hydrolysates from : Optimal Process and Bioactive Properties

Authors: Sara A Cunha, Ezequiel R Coscueta, Paulo Nova, Joana Laranjeira Silva, Maria Manuela Pintado

Journal: Molecules

PubMed ID: 35458702

Doi: 10.3390/molecules27082505

Products & Services: Catalog Peptides

A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells

Authors: Yumei Li, Lingjun Wu, Yueying Liu, Siwen Ma, Biyi Huang, Xianjing Feng, Hui Wang

Journal: Transl Oncol

PubMed ID: 35477065

Doi: 10.1016/j.tranon.2022.101424

Products & Services: Mammalian Expression

The Model for Mucolipidosis Type IV

Authors: Claire Y Allan, Paul R Fisher

Journal: Front Cell Dev Biol

PubMed ID: 35493081

Doi: 10.3389/fcell.2022.741967

Products & Services: Protein and Antibody Isolation

Role of Chitinase-3-like Protein 1 in Cardioprotection and Angiogenesis by Post-Infarction Exercise Training

Authors: Zhuo Li, Fangnan Wu, Lei Xi, Zhenjun Tian

Journal: Biomedicines

PubMed ID: 35625766

Doi: 10.3390/biomedicines10051028

Products & Services: Protein Electrophoresis and Western

Measles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract

Authors: Drishya Kurup, Christoph Wirblich, Rachael Lambert, Leila Zabihi Diba, Benjamin E Leiby, Matthias J Schnell

Journal: npj Vaccines

PubMed ID: 35440656

Doi: 10.1038/s41541-022-00464-2

Products & Services: Gene Synthesis

Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action

Authors: Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A Zubarev, Stig Linder, Pádraig D'Arcy

Journal: Front Oncol

PubMed ID: 35530310

Doi: 10.3389/fonc.2022.852980

Products & Services: Oligo pool

Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota

Authors: Matthew P Ostrowski, Sabina Leanti La Rosa, Benoit J Kunath, Andrew Robertson, Gabriel Pereira, Live H Hagen, Neha J Varghese, Ling Qiu, Tianming Yao, Gabrielle Flint, James Li, Sean P McDonald, Duna Buttner, Nicholas A Pudlo, Matthew K Schnizlein, Vincent B Young, Harry Brumer, Thomas M Schmidt, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Bruce Hamaker, Emiley A Eloe-Fadrosh, Ashootosh Tripathi, Phillip B Pope, Eric C Martens

Journal: Nat Microbiol

PubMed ID: 35365790

Doi: 10.1038/s41564-022-01093-0

Products & Services: Gene Fragments