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LIMP2 gene, evolutionarily conserved regulation by TFE3, relieves lysosomal stress induced by cholesterol

Authors: Hanze Guo, Yingying Zhu, Jiarui Li, Qipeng Zhang, Yan Chi

Journal: Life Sci

PubMed ID: 35987341

Doi: 10.1016/j.lfs.2022.120888

Products & Services: Custom Vector Construction

Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase

Authors: Samantha N Muellers, Mattias M Nyitray, Nicholas Reynarowych, Edina Saljanin, Annie Laurie Benzie, Alan R Schoenfeld, Brian J Stockman, Karen N Allen

Journal: Biochemistry

PubMed ID: 35994320

Doi: 10.1021/acs.biochem.2c00361

Products & Services: Recombinant Proteins

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

Authors: Jeroen M J Tas, Ja-Hyun Koo, Ying-Cing Lin, Zhenfei Xie, Jon M Steichen, Abigail M Jackson, Blake M Hauser, Xuesong Wang, Christopher A Cottrell, Jonathan L Torres, John E Warner, Kathrin H Kirsch, Stephanie R Weldon, Bettina Groschel, Bartek Nogal, Gabriel Ozorowski, Sandhya Bangaru, Nicole Phelps, Yumiko Adachi, Saman Eskandarzadeh, Michael Kubitz, Dennis R Burton, Daniel Lingwood, Aaron G Schmidt, Usha Nair, Andrew B Ward, William R Schief, Facundo D Batista

Journal: Immunity

PubMed ID: 35987201

Doi: 10.1016/j.immuni.2022.07.020

Products & Services: Catalog Antibodies

Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers

Authors: Yuqiu Xu, Zhuang Wei, Mei Feng, Dexiang Zhu, Shenglin Mei, Zhongen Wu, Qingyang Feng, Wenju Chang, Meiling Ji, Chenglong Liu, Yuanyuan Zhu, Lian Shen, Fan Yang, Yijiao Chen, Yuxiong Feng, Jianmin Xu, Di Zhu

Journal: Cell Rep

PubMed ID: 36044847

Doi: 10.1016/j.celrep.2022.111295

Products & Services: Recombinant Proteins

Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway

Authors: Haitao Liu, Sha Zhang, Yi Liu, Jing Ma, Wei Chen, Tao Yin, Tongbin Li, Bin Liang, Ling Tao

Journal: Respir Res

PubMed ID: 35986277

Doi: 10.1186/s12931-022-02124-4

Products & Services: Plasmid DNA Preparation

Post-translational control of beige fat biogenesis by PRDM16 stabilization

Authors: Qiang Wang, Huixia Li, Kazuki Tajima, Anthony R P Verkerke, Zachary H Taxin, Zhishuai Hou, Joanne B Cole, Fei Li, Jake Wong, Ichitaro Abe, Rachana N Pradhan, Tadashi Yamamuro, Takeshi Yoneshiro, Joel N Hirschhorn, Shingo Kajimura

Journal: Nature

PubMed ID: 35978186

Doi: 10.1038/s41586-022-05067-4

Products & Services: Custom DNA/RNA Oligos

Immunological profiles associated with distinct parasitemic states in volunteers undergoing malaria challenge in Gabon

Authors: Mikhael D Manurung, Sanne E de Jong, Yvonne Kruize, Yoanne D Mouwenda, Madeleine Eunice Betouke Ongwe, Yabo Josiane Honkpehedji, Jeannot Frézus Zinsou, Jean Claude Dejon-Agobe, Stephen L Hoffman, Peter G Kremsner, Ayola Akim Adegnika, Rolf Fendel, Benjamin Mordmüller, Meta Roestenberg, Bertrand Lell, Maria Yazdanbakhsh

Journal: Sci Rep

PubMed ID: 35922467

Doi: 10.1038/s41598-022-17725-8

Products & Services: Protein and Antibody Isolation

Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors

Authors: Sanghyun P Kim, Nolan R Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C Deniger, Frank J Lowery, Maria R Parkhurst, Lien T Ngo, Satyajit Ray, Yong F Li, Victoria Hill, Maria Florentin, Robert V Masi, Biman C Paria, Noam Levin, Alakesh Bera, Elizabeth A Hedges, Agnes Choi, Praveen D Chatani, Anup Y Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D Prickett, Li Jia, Jonathan M Hernandez, Chuong D Hoang, Paul F Robbins, Stephanie L Goff, Richard M Sherry, James C Yang, Steven A Rosenberg

Journal: Cancer Immunol Res

PubMed ID: 35749374

Doi: 10.1158/2326-6066.CIR-22-0040

Products & Services: Peptide Synthesis

Optimized production and fluorescent labeling of SARS-CoV-2 virus-like particles

Authors: Manon Gourdelier, Jitendriya Swain, Coline Arone, Anita Mouttou, David Bracquemond, Peggy Merida, Saveez Saffarian, Sébastien Lyonnais, Cyril Favard, Delphine Muriaux

Journal: Sci Rep

PubMed ID: 36030323

Doi: 10.1038/s41598-022-18681-z

Products & Services: Plasmid DNA Preparation

Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects

Authors: Mohanraj Gopalswamy, Tobias Kroeger, David Bickel, Benedikt Frieg, Shahina Akter, Stephan Schott-Verdugo, Aldino Viegas, Thomas Pauly, Manuela Mayer, Julia Przibilla, Jens Reiners, Luitgard Nagel-Steger, Sander H J Smits, Georg Groth, Manuel Etzkorn, Holger Gohlke

Journal: Sci Rep

PubMed ID: 35986043

Doi: 10.1038/s41598-022-17913-6

Products & Services: Protein and Antibody Isolation