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The PSI Domain of the MET Oncogene Encodes a Functional Disulfide Isomerase Essential for the Maturation of the Receptor Precursor

Authors: Dogus Murat Altintas, Simona Gallo, Cristina Basilico, Marina Cerqua, Alessio Bocedi, Annapia Vitacolonna, Orsola Botti, Elena Casanova, Ilaria Rancati, Chiara Milanese, Sara Notari, Giorgia Gambardella, Giorgio Ricci, Pier Giorgio Mastroberardino, Carla Boccaccio, Tiziana Crepaldi, Paolo Maria Comoglio

Journal: Int J Mol Sci

PubMed ID: 36293286

Doi: 10.3390/ijms232012427

Products & Services: Codon Optimization

COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

Authors: Giorgia Benegiamo, Maroun Bou Sleiman, Martin Wohlwend, Sandra Rodríguez-López, Ludger J E Goeminne, Pirkka-Pekka Laurila, Marie Klevjer, Minna K Salonen, Jari Lahti, Pooja Jha, Sara Cogliati, José Antonio Enriquez, Ben M Brumpton, Anja Bye, Johan G Eriksson, Johan Auwerx

Journal: Nat Metab

PubMed ID: 36253618

Doi: 10.1038/s42255-022-00655-0

Products & Services: Mammalian Expression

Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium

Authors: Léa Conchou, Bastien Doumèche, Frédéric Galisson, Sébastien Violot, Chloé Dugelay, Eric Diesis, Adeline Page, Anne-Lise Bienvenu, Stéphane Picot, Nushin Aghajari, Lionel Ballut

Journal: Commun Biol

PubMed ID: 36316540

Doi: 10.1038/s42003-022-04091-4

Products & Services: Custom Vector Construction

APC/CCdc20-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset

Authors: Federico Zucca, Clara Visintin, Jiaming Li, Steven P Gygi, Rosella Visintin

Journal: J Cell Biol

PubMed ID: 36269172

Doi: 10.1083/jcb.202203089

Products & Services: Catalog Peptides

EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases

Authors: Ruite Xiang, Laura Fernandez-Lopez, Ana Robles-Martín, Manuel Ferrer, Victor Guallar

Journal: Biomolecules

PubMed ID: 36291739

Doi: 10.3390/biom12101529

Products & Services: Recombinant Proteins

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

Authors: Shuang Yang, Giorgos Hiotis, Yi Wang, Junjian Chen, Jia-Huai Wang, Mikyung Kim, Ellis L Reinherz, Thomas Walz

Journal: Nat Commun

PubMed ID: 36302771

Doi: 10.1038/s41467-022-34008-y

Products & Services: Protein and Antibody Isolation

Development of a simple PCR-RFLP technique for detection and differentiation of E histolytica, E dispar and E moshkovskii

Authors: Sanjib K Sardar, Seiki Kobayashi, Koushik Das, Yumiko Saito-Nakano, Shanta Dutta, Tomoyoshi Nozaki, Sandipan Ganguly

Journal: Parasitol Res

PubMed ID: 36308533

Doi: 10.1007/s00436-022-07706-1

Products & Services: Molecular Biology Tools

Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein

Authors: Xiaodong Luan, Xinming Li, Yufan Li, Gengchen Su, Wanchao Yin, Yi Jiang, Ning Xu, Feng Wang, Wang Cheng, Ye Jin, Leike Zhang, H. Eric Xu, Yi Xue, Shuyang Zhang

Journal: Science Bulletin

Doi: 10.1016/j.scib.2022.10.021

Products & Services: Gene Synthesis

mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts

Authors: Denzil Furtado, Christina Cortez-Jugo, Ya Hui Hung, Ashley I Bush, Frank Caruso

Journal: Mol Pharm

PubMed ID: 36125338

Doi: 10.1021/acs.molpharmaceut.2c00463

Products & Services: Gene Fragments

A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity

Authors: Lian-Sheng Cheng, Yong-Feng Cheng, Wen-Ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang, Guodong Shen

Journal: J Transl Med

PubMed ID: 36076251

Doi: 10.1186/s12967-022-03619-w

Products & Services: Mammalian Expression