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Sniper2L is a high-fidelity Cas9 variant with high activity

Authors: Young-Hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Seung-Min Bae, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Benjamin P Kleinstiver, Jungjoon K Lee, Taekjip Ha, Hyongbum Henry Kim

Journal: Nat Chem Biol

PubMed ID: 36894722

Doi: 10.1038/s41589-023-01279-5

Products & Services: Protein and Antibody Isolation

Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults

Authors: Amy C Thomas, Elizabeth Oliver, Holly E Baum, Kapil Gupta, Kathryn L Shelley, Anna E Long, Hayley E Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L Relton, Ashley Toye, Derek N Woolfson, Imre Berger, Anu Goenka, Andrew D Davidson, Kathleen M Gillespie, Alistair J K Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday

Journal: Commun Med (Lond)

PubMed ID: 36922542

Doi: 10.1038/s43856-023-00264-2

Products & Services: Protein and Antibody Isolation

Process development and characterization of recombinant nucleocapsid protein for its application on COVID-19 diagnosis

Authors: Luãnna Elisa Liebscher Vidal, Janaina Figueira-Mansur, Patrícia Barbosa Jurgilas, Ana Paula Correa Argondizzo, Cristiane Pinheiro Pestana, Fernanda Otaviano Martins, Haroldo Cid da Silva Junior, Mariana Miguez, Bernardo Oliveira Loureiro, Christiane de Fátima Silva Marques, Karen Soares Trinta, Leila Botelho Rodrigues da Silva, Marcelle Bral de Mello, Edimilson Domingos da Silva, Renata Chagas Bastos, Gabriela Esteves

Journal: Protein Expr Purif

PubMed ID: 36921810

Doi: 10.1016/j.pep.2023.106263

Products & Services: Molecular Biology Reagents

COVID-19 vaccines based on viral nanoparticles displaying a conserved B-cell epitope show potent immunogenicity and a long-lasting antibody response

Authors: Jessica Fernanda Affonso de Oliveira; Zhongchao Zhao; Yi Xiang; Matthew D. Shin; Kathleen Elizabeth Villase or; Xinyi Deng; Sourabh Shukla; Shaochen Chen; Nicole F. Steinmetz

Journal: Frontiers in Microbiology

PubMed ID: 37152732

Doi: 10.3389/fmicb.2023.1117494

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, Joke Vanden Berghe, Niek Sanders, Ben Wielockx, Rudi Beyaert, Claude Libert

Journal: Front Immunol

PubMed ID: 37006237

Doi: 10.3389/fimmu.2023.1124011

Products & Services: Protein and Antibody Isolation

Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r

Authors: Brianne E Hoglin, Marin V Miner, Ugumuur Erbenebayar, Ciaran A Shaughnessy, Robert M Dores

Journal: Gen Comp Endocrinol

PubMed ID: 36996927

Doi: 10.1016/j.ygcen.2023.114278

Products & Services: Protein and Antibody Isolation

IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity

Authors: Anastasia Geladaris, Silke Häusser-Kinzel, Roxanne Pretzsch, Nitzan Nissimov, Klaus Lehmann-Horn, Darius Häusler, Martin S Weber

Journal: Acta Neuropathol

PubMed ID: 36854993

Doi: 10.1007/s00401-023-02552-6

Products & Services: Protein and Antibody Isolation

IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway

Authors: Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang

Journal: Exp Ther Med

PubMed ID: 37006880

Doi: 10.3892/etm.2023.11868

Products & Services: Protein and Antibody Isolation

miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathways

Authors: Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, Leilei Zhang, Zhinan Hong, Ning Zhang, Haibin Wang, Wuyin Li

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 36942990

Doi: 10.3724/abbs.2023016

Products & Services: Protein and Antibody Isolation

The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity

Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer

Journal: Virus Res

PubMed ID: 36948228

Doi: 10.1016/j.virusres.2023.199099

Products & Services: Protein and Antibody Isolation