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A highly efficient transgene knock-in technology in clinically relevant cell types

Authors: Alexander G Allen, Samia Q Khan, Carrie M Margulies, Ramya Viswanathan, Swarali Lele, Laura Blaha, Sean N Scott, Kaitlyn M Izzo, Alexandra Gerew, Rithu Pattali, Nadire R Cochran, Carl S Holland, Amy H Zhao, Stephen E Sherman, Michael C Jaskolka, Meng Wu, Aaron C Wilson, Xiaoqi Sun, Dawn M Ciulla, Deric Zhang, Jacqueline D Nelson, Peisheng Zhang, Patrizia Mazzucato, Yan Huang, Georgia Giannoukos, Eugenio Marco, Michael Nehil, John A Follit, Kai-Hsin Chang, Mark S Shearman, Christopher J Wilson, John A Zuris

Journal: Nat Biotechnol

PubMed ID: 37127662

Doi: 10.1038/s41587-023-01779-8

Products & Services: Gene Synthesis

Structure of a 10-23 Deoxyribozyme Exhibiting a Homodimer Conformation

Authors: Evan Cramer, Sarah Starcovic, Rebekah Avey, Ali Kaya, Aaron Robart

Journal: Res Sq

PubMed ID: 37398199

Doi: 10.21203/rs.3.rs-2252941/v1

Products & Services: Gene Synthesis

Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network

Authors: Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White

Journal: Life Sci Alliance

PubMed ID: 37169593

Doi: 10.26508/lsa.202201466

Products & Services: Stable Cell Lines

Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy

Authors: Nikolas T Martin, Mathieu J F Crupi, Zaid Taha, Joanna Poutou, Jack T Whelan, Sydney Vallati, Julia Petryk, Ricardo Marius, Bradley Austin, Taha Azad, Mason Boulanger, Tamara Burgess, Ilson Sanders, Camille Victoor, Bryan C Dickinson, Jean-Simon Diallo, Carolina S Ilkow, John C Bell

Journal: Pharmaceuticals (Basel)

PubMed ID: 37242495

Doi: 10.3390/ph16050709

Products & Services: Recombinant Proteins

Evaluation of humoral and cellular immune responses induced by a cocktail of recombinant African swine fever virus antigens fused with OprI in domestic pigs

Authors: Guanglei Zhang, Wei Liu, Sicheng Yang, Shuai Song, Yunyun Ma, Guangqing Zhou, Xiaxia Liang, Chun Miao, Junhui Li, Yanhong Liu, Junjun Shao, Huiyun Chang

Journal: Virol J

PubMed ID: 37237390

Doi: 10.1186/s12985-023-02070-7

Products & Services: DNA Sequencing

Preparation of magnetic polyacrylamide hydrogel with chitosan for immobilization of glutamate decarboxylase to produce γ-aminobutyric acid

Authors: Jianjun Wang, Luyao Wang, Chengli Yang, Yihui Zhu, Ziqian Chen, Guanya He, Kaishun Hu, Kaixuan Liu, Beibei Fang, Dali Li, Ruofu Shi

Journal: Prep Biochem Biotechnol

PubMed ID: 37184437

Doi: 10.1080/10826068.2023.2209884

Products & Services: Protein and Antibody Isolation

Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest

Authors: Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi

Journal: Life Sci Alliance

PubMed ID: 37197981

Doi: 10.26508/lsa.202201685

Products & Services: Molecular Biology Reagents

Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities

Authors: Heng Zhang, Jianfeng Yan, Zhike Lu, Yangfan Zhou, Qingfeng Zhang, Tingting Cui, Yini Li, Hui Chen, Lijia Ma

Journal: Cell Discov

PubMed ID: 37193681

Doi: 10.1038/s41421-023-00549-9

Products & Services: Gene Synthesis

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant

Authors: Nanami Senoo, Dinesh K Chinthapalli, Matthew G Baile, Vinaya K Golla, Bodhisattwa Saha, Oluwaseun B Ogunbona, James A Saba, Teona Munteanu, Yllka Valdez, Kevin Whited, Dror Chorev, Nathan N Alder, Eric R May, Carol V Robinson, Steven M Claypool

Journal: biorxiv

PubMed ID: 37205478

Doi: 10.1101/2023.05.05.539595

Products & Services: Molecular Biology Reagents

Arabidopsis calmodulin-like proteins CML13 and CML14 interact with proteins that have IQ domains

Authors: Howard J Teresinski, Bryan Hau, Kyle Symonds, Ryan Kilburn, Kim A Munro, Nathan M Doner, Robert Mullen, Vivian H Li, Wayne A Snedden

Journal: Plant Cell Environ

PubMed ID: 37222394

Doi: 10.1111/pce.14616

Products & Services: Catalog Antibodies