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Small-molecule caspase-1 inhibitor CZL80 terminates refractory status epilepticus via inhibition of glutamatergic transmission

Authors: Fei Wang, Yu Wang, Qing-Yang Zhang, Ke-Yu Hu, Ying-Jie Song, Lin Yang, Fan Fei, Ceng-Lin Xu, Sun-Liang Cui, Ye-Ping Ruan, Yi Wang, Zhong Chen

Journal: Acta Pharmacol Sin

PubMed ID: 38514863

Doi: 10.1038/s41401-024-01257-0

Products & Services: Protein Electrophoresis and Western

Occlusal force orchestrates alveolar bone homeostasis via Piezo1 in female mice

Authors: Yiling Yang, Qinggang Dai, Xin Gao, Yanfei Zhu, Mi Ri Chung, Anting Jin, Yuanqi Liu, Xijun Wang, Xiangru Huang, Siyuan Sun, Hongyuan Xu, Jingyi Liu, Lingyong Jiang

Journal: J Bone Miner Res

PubMed ID: 38477783

Doi: 10.1093/jbmr/zjae032

Products & Services: Protein Electrophoresis and Western

Ultrasound-mediated gene delivery specifically targets liver sinusoidal endothelial cells for sustained FVIII expression in hemophilia A mice

Authors: Savannah M Lawton, Megan A Manson, Meng-Ni Fan, Ting-Yen Chao, Chun-Yu Chen, Peter Kim, Carley Campbell, Xiaohe Cai, Amber Vander Kooi, Carol H Miao

Journal: Mol Ther

PubMed ID: 38341614

Doi: 10.1016/j.ymthe.2024.02.010

Products & Services: Protein Electrophoresis and Western

Characterization of cleavage patterns and assembly of N-terminally modified GII6 norovirus VP1 proteins

Authors: Jie Ma, Jinjin Liu, Yuqi Huo

Journal: Arch Virol

PubMed ID: 38386207

Doi: 10.1007/s00705-024-05973-0

Products & Services: Protein Electrophoresis and Western

The CRL5–SPSB3 ubiquitin ligase targets nuclear cGAS for degradation

Authors: Pengbiao Xu , Ying Liu , Chong Liu , Baptiste Guey , Lingyun Li , Pauline Melenec , Jonathan Ricci , Andrea Ablasser

Journal: Nature

PubMed ID: 38418882

Doi: 10.1038/s41586-024-07112-w

Products & Services: Antibody Modification and Purification Services

Effects of polyphenol and gelatin types on the physicochemical properties and emulsion stabilization of polyphenol-crosslinked gelatin conjugates

Authors: Wenjuan Wu, Cuiping Shi, Ye Zi, Huan Gong, Lijia Chen, Guangyi Kan, Xichang Wang, Jian Zhong

Journal: Food Chem X

PubMed ID: 38440057

Doi: 10.1016/j.fochx.2024.101250

Products & Services: Protein Electrophoresis and Western

Generation and Application of Monoclonal Antibodies against Porcine S100A8, S100A9, and S100A12 Proteins Using Hybridoma Technology

Authors: Pengpeng Xia, Xin Ma, Li Yan, Siqi Lian, Xiangyu Li, Yi Luo, Ziyue Chen, Xingduo Ji

Journal: Int J Mol Sci

PubMed ID: 38256103

Doi: 10.3390/ijms25021029

Products & Services: Protein Electrophoresis and Western

Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells

Authors: Chuwen Li, Haiyan Guo, Peisong Zhai, Ming Yan, Chun Liu, Xiaoning Wang, Chaoji Shi, Jiang Li, Tong Tong, Zhiyuan Zhang, Hailong Ma, Jianjun Zhang

Journal: Cancer Res

PubMed ID: 37930937

Doi: 10.1158/0008-5472.CAN-23-1448

Products & Services: Protein Electrophoresis and Western

Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites

Authors: Bingsen Zhang, James Mullmann, Andreas H. Ludewig, Irma R. Fernandez, Tyler R. Bales, Robert S. Weiss & Frank C. Schroeder

Journal: Nature Chemical Biology

PubMed ID: 38167917

Doi: 10.1038/s41589-023-01511-2

Products & Services: Antibody Modification and Purification Services

Cell death induced by nicotine in human neuroblastoma SH-SY5Y cells is mainly attributed to cytoplasmic vacuolation originating from the trans-Golgi network

Authors: Jun Li, Hongjuan Wang, Huan Chen, Xiao Li, Yong Liu, Hongwei Hou, Qingyuan Hu