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A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4 T-cell immunity

Authors: François Anna, Jodie Lopez, Fanny Moncoq, Catherine Blanc, Pierre Authié, Amandine Noirat, Ingrid Fert, Philippe Souque, Fabien Nevo, Alexandre Pawlik, David Hardy, Sophie Goyard, Denis Hudrisier, Roland Brosch, Françoise Guinet, Olivier Neyrolles, Pierre Charneau, Laleh Majlessi

Journal: Mucosal Immunol

PubMed ID: 36104497

Doi: 10.1038/s41385-022-00566-z

Products & Services: Codon Optimization

Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer

Authors: Duy T Nguyen, Wei Yang, Arun Renganathan, Cody Weimholt, Duminduni H Angappulige, Thanh Nguyen, Robert W Sprung, Gerald L Andriole, Eric H Kim, Nupam P Mahajan, Kiran Mahajan

Journal: Clin Cancer Res

PubMed ID: 35849143

Doi: 10.1158/1078-0432.CCR-21-3603

Products & Services: Peptide Synthesis

HSC70 is a novel binding partner involved in the capture of immunoglobulins on B cells in the NOD mouse

Authors: Emma Renman, Rifat Ekici, Mia Sundström, Kristina Lejon

Journal: Autoimmunity

PubMed ID: 36120986

Doi: 10.1080/08916934.2022.2117307

Products & Services: Recombinant Proteins

Kinetic Characterization and Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferases

Authors: Kayla Glockzin, Demetrios Kostomiris, Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Sinan Gai, Joshua N Buckler, Vern L Schramm, Peter C Tyler, Thomas D Meek, Ardala Katzfuss

Journal: Biochemistry

PubMed ID: 36193631

Doi: 10.1021/acs.biochem.2c00312

Products & Services: Custom Vector Construction

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis

Authors: Marcela A Ferrada, Sinisa Savic, Daniela Ospina Cardona, Jason C Collins, Hugh Alessi, Fernanda Gutierrez-Rodrigues, Dinesh Babu Uthaya Kumar, Lorena Wilson, Wendy Goodspeed, James S Topilow, Julie J Paik, James A Poulter, Tanaz A Kermani, Matthew J Koster, Kenneth J Warrington, Catherine Cargo, Rachel S Tattersall, Christopher J A Duncan, Anna Cantor, Patrycja Hoffmann, Elspeth M Payne, Hanna Bonnekoh, Karoline Krause, Edward W Cowen, Katherine R Calvo, Bhavisha A Patel, Amanda K Ombrello, Daniel L Kastner, Neal S Young, Achim Werner, Peter C Grayson, David B Beck

Journal: Blood

PubMed ID: 35793467

Doi: 10.1182/blood.2022016985

Products & Services: Gene Synthesis

Structure of the PAPP-A complex reveals mechanism of substrate recognition

Authors: Russell A Judge, Janani Sridar, Kathryn Tunyasuvunakool, Rinku Jain, John C K Wang, Christna Ouch, Jun Xu, Amirhossein Mafi, Aaron H Nile, Clint Remarcik, Corey L Smith, Crystal Ghosh, Chen Xu, Vincent Stoll, John Jumper, Amoolya H Singh, Dan Eaton, Qi Hao

Journal: Nat Commun

PubMed ID: 36127359

Doi: 10.1038/s41467-022-33175-2

Products & Services: Protein and Antibody Isolation

The structure of a polyketide synthase bimodule core

Authors: Yves U Tittes, Dominik A Herbst, Solène F X Martin, Hugo Munoz-Hernandez, Roman P Jakob, Timm Maier

Journal: Sci Adv

PubMed ID: 36129979

Doi: 10.1126/sciadv.abo6918

Products & Services: Protein and Antibody Isolation

Multiplex real-time PCR for the detection and differentiation of equid gammaherpesvirus 2 and 5

Authors: Flavia Fürer, Cornel Fraefel, Julia Lechmann