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Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity

Authors: Benedikt Goretzki, Christoph Wiedemann, Brett A McCray, Stefan L Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K Donohue, Cy M Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J Sumner, Gerhard Hummer, Ute A Hellmich

Journal: Nat Commun

PubMed ID: 37443299

Doi: 10.1038/s41467-023-39808-4

Products & Services: Plasmid DNA Preparation

Absolute Quantification of Photoreceptor Outer Segment Proteins

Authors: Nikolai P Skiba, Tylor R Lewis, William J Spencer, Carson M Castillo, Andrej Shevchenko, Vadim Y Arshavsky

Journal: J Proteome Res

PubMed ID: 37493966

Doi: 10.1021/acs.jproteome.3c00267

Products & Services: Peptide Synthesis

Computationally Designed Small Molecules Disassemble Both Soluble Oligomers and Protofibrils of Amyloid β-Protein Responsible for Alzheimer's Disease

Authors: Yingying Jin, Matthew A Downey, Ambuj Singh, Steven K Buratto, Michael T Bowers

Journal: ACS Chem Neurosci

PubMed ID: 37442126

Doi: 10.1021/acschemneuro.3c00266

Products & Services: Protein and Antibody Isolation

Notch Intracellular Domains form Transcriptionally Active Heterodimeric Complexes on Sequence-paired Sites

Authors: Tana R Gazdik, Jacob J Crow, Tyler Lawton, Chloe J Munroe, Hannah Theriault, Travis M Wood, Allan R Albig

Journal: Res Sq

PubMed ID: 37546896

Doi: 10.21203/rs.3.rs-3147210/v1

Products & Services: Protein and Antibody Isolation

Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1

Authors: Eva-Maria Thüring, Christian Hartmann, Janesha C Maddumage, Airah Javorsky, Birgitta E Michels, Volker Gerke, Lawrence Banks, Patrick O Humbert, Marc Kvansakul, Klaus Ebnet

Journal: Commun Biol

PubMed ID: 37430142

Doi: 10.1038/s42003-023-05088-3

Products & Services: Peptide Synthesis Peptide Synthesis

Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis

Authors: Aleksandra W Debowski, Nicole M Bzdyl, David R Thomas, Nichollas E Scott, Christopher H Jenkins, Jua Iwasaki, Emily A Kibble, Chen Ai Khoo, Nicolas J Scheuplein, Pamela M Seibel, Theresa Lohr, Georgie Metters, Charles S Bond, Isobel H Norville, Keith A Stubbs, Nicholas J Harmer, Ulrike Holzgrabe, Hayley J Newton, Mitali Sarkar-Tyson

Journal: PLoS Pathog

PubMed ID: 37399210

Doi: 10.1371/journal.ppat.1011491

Products & Services: Protein and Antibody Isolation

Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins

Authors: Ashley P Viera Ortiz, Gregory Cajka, Olamide A Olatunji, Bailey Mikytuck, Ophir Shalem, Edward B Lee

Journal: Brain

PubMed ID: 36516294

Doi: 10.1093/brain/awac479

Products & Services: DNA Sequencing

Investigating the aggregation perspective of Dengue virus proteome

Authors: Shivani Krishna Kapuganti, Kumar Udit Saumya, Deepanshu Verma, Rajanish Giri

Journal: Virology

PubMed ID: 37473502

Doi: 10.1016/j.virol.2023.07.010

Products & Services: Peptide Synthesis

N6-Methyladenosine Promotes Translation of VEGFA to Accelerate Angiogenesis in Lung Cancer

Authors: Haisheng Zhang, Jiawang Zhou, Jiexin Li, Zhaotong Wang, Zhuojia Chen, Ziyan Lv, Lichen Ge, Guoyou Xie, Guoming Deng, Yalan Rui, Hongbing Huang, Likun Chen, Hongsheng Wang

Journal: Cancer Res

PubMed ID: 37103476

Doi: 10.1158/0008-5472.CAN-22-2449

Products & Services: Custom RNAi Services

Viral manipulation of cell polarity signalling

Authors: Airah Javorsky, Patrick O Humbert, Marc Kvansakul

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 37437846

Doi: 10.1016/j.bbamcr.2023.119536

Products & Services: Molecular Biology Reagents