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Evolutionary adaptation of the protein folding pathway for secretability
Authors: Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou
Journal: EMBO J
PubMed ID: 36031863
Doi: 10.15252/embj.2022111344
Products & Services: Custom Vector Construction   
Dipeptidyl peptidase 9 triggers BRCA2 degradationand promotes DNA damage repair
Authors: Oguz Bolgi 1 2, Maria Silva-Garcia 2, Breyan Ross 3 4, Esther Pilla 2, Vijayalakshmi Kari 5, Markus Killisch 2, Melanie Spitzner 5, Nadine Stark 6, Christof Lenz 7 8, Konstantin Weiss 9, Laura Donzelli 1, Mark D Gorrell 10, Marian Grade 5, Jan Riemer 9, Henning Urlaub 7 8, Matthias Dobbelstein 6, Robert Huber 3 11 12, Ruth Geiss-Friedlander 1 2
Journal: EMBO Rep
PubMed ID: 35912982
Doi: 10.15252/embr.202154136
Products & Services: Peptide Synthesis   
Regulation of Host Immune Response against Proteins via Computational mRNA Vaccine Design through Transcriptional Modification
Authors: Muhammad Naveed, Khizra Jabeen, Rubina Naz, Muhammad Saad Mughal, Ali A Rabaan, Muhammed A Bakhrebah, Fahad M Alhoshani, Mohammed Aljeldah, Basim R Al Shammari, Mohammed Alissa, Amal A Sabour, Rana A Alaeq, Maha A Alshiekheid, Mohammed Garout, Mohammed S Almogbel, Muhammad A Halwani, Safaa A Turkistani, Naveed Ahmed
Journal: Microorganisms
PubMed ID: 36014038
Doi: 10.3390/microorganisms10081621
Products & Services: Molecular Biology Tools   
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity
Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol
Journal: Biochemistry
PubMed ID: 35951410
Doi: 10.1021/acs.biochem.2c00323
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results
Authors: Christine D Palmer, Amy R Rappaport, Matthew J Davis, Meghan G Hart, Ciaran D Scallan, Sue-Jean Hong, Leonid Gitlin, Lauren D Kraemer, Sonia Kounlavouth, Aaron Yang, Lindsey Smith, Desiree Schenk, Mojca Skoberne, Kiara Taquechel, Martina Marrali, Jason R Jaroslavsky, Charmaine N Nganje, Elizabeth Maloney, Rita Zhou, Daniel Navarro-Gomez, Adrienne C Greene, Gijsbert Grotenbreg, Renee Greer, Wade Blair, Minh Duc Cao, Shawn Chan, Kyounghwa Bae, Alexander I Spira, Sameek Roychowdhury, David P Carbone, Brian S Henick, Charles G Drake, Benjamin J Solomon, Daniel H Ahn, Amit Mahipal, Steve B Maron, Benny Johnson, Raphael Rousseau, Roman Yelensky, Chih-Yi Liao, Daniel V T Catenacci, Andrew Allen, Andrew R Ferguson, Karin Jooss
Journal: Nat Med
PubMed ID: 35970920
Doi: 10.1038/s41591-022-01937-6
Products & Services: Plasmid DNA Preparation   
Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits
Authors: Changjin Liu, Min Lin, Huanyi Hu, Xiaolan Liu, Yanchao Bian, Xiaohua Huang, Xiaoxiang Li, Wenyang Yu, Feng Luo, Shunzhou Deng
Journal: Front Microbiol
PubMed ID: 35992711
Doi: 10.3389/fmicb.2022.960374
Products & Services: Plasmid DNA Preparation   
Investigation of Transcript Variant 6 of as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer
Authors: Xin Zhang, Daniel O'Brien, Xiaohui Zhang
Journal: Oxid Med Cell Longev
PubMed ID: 36071863
Doi: 10.1155/2022/7078787
Products & Services: Plasmid DNA Preparation   
Resolving the zinc binding capacity of honey bee vitellogenin and locating its putative binding sites
Authors: Vilde Leipart, Øyvind Enger, Diana Cornelia Turcu, Olena Dobrovolska, Finn Drabløs, Øyvind Halskau, Gro V Amdam
Journal: Insect Mol Biol
PubMed ID: 36054587
Doi: 10.1111/imb.12807
Products & Services: PCR Cloning and Subcloning   
Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster
Authors: Julia R Port, Dylan H Morris, Jade C Riopelle, Claude Kwe Yinda, Victoria A Avanzato, Myndi G Holbrook, Trenton Bushmaker, Jonathan E Schulz, Taylor A Saturday, Kent Barbian, Colin A Russell, Rose Perry-Gottschalk, Carl I Shaia, Craig Martens, James O Lloyd-Smith, Robert J Fischer, Vincent J Munster
Journal: biorxiv
PubMed ID: 36032963
Doi: 10.1101/2022.08.15.504010
Products & Services: DNA Sequencing   
Dysregulated naive B cells and de novo autoreactivity in severe COVID-19
Authors: Matthew C Woodruff, Richard P Ramonell, Natalie S Haddad, Fabliha A Anam, Mark E Rudolph, Tiffany A Walker, Alexander D Truong, Adviteeya N Dixit, Jenny E Han, Monica Cabrera-Mora, Martin C Runnstrom, Regina Bugrovsky, Jennifer Hom, Erin C Connolly, Igor Albizua, Vidhi Javia, Kevin S Cashman, Doan C Nguyen, Shuya Kyu, Ankur Singh Saini, Michael Piazza, Christopher M Tipton, Arezou Khosroshahi, Greg Gibson, Greg S Martin, Cheryl L Maier, Annette Esper, Scott A Jenks, F Eun-Hyung Lee, Ignacio Sanz
Journal: Nature
PubMed ID: 36044993
Doi: 10.1038/s41586-022-05273-0
Products & Services: Bacterial Expression   

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