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Evolutionary adaptation of the protein folding pathway for secretability
Authors: Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou
Journal: EMBO J
PubMed ID: 36031863
Doi: 10.15252/embj.2022111344
Products & Services: Custom Vector Construction   
Disruption of nuclear envelope integrity as a possible initiating event in tauopathies
Authors: Marine Prissette, Wen Fury, Matthew Koss, Claudia Racioppi, Daria Fedorova, Ella Dragileva, Georgia Clarke, Taylor Pohl, John Dugan, Diana Ahrens, Joyce Chiu, Charleen Hunt, Chia-Jen Siao, Tara Young, Arijit Bhowmick, Vitaliy Rogulin, Mathieu Desclaux, Eric Y Hayden, Michael Podgorski, Min Gao, Lynn E Macdonald, David Frendewey, George D Yancopoulos, Brian Zambrowicz
Journal: Cell Rep
PubMed ID: 36001963
Doi: 10.1016/j.celrep.2022.111249
Products & Services: Synthetic sgRNA and crRNA Service   
Microporous affinity membranes and their incorporation into microfluidic devices for monitoring of therapeutic antibodies
Authors: Joshua D Berwanger, Melinda A Lake, Sanniv Ganguly, Junyan Yang, Christopher J Welch, Jacqueline C Linnes, Merlin Bruening
Journal: Talanta
PubMed ID: 36030739
Doi: 10.1016/j.talanta.2022.123842
Products & Services: Proteins, Expression, Isolation and Analysis   
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
Authors: Timothy A Klein, Dirk W Grebenc, Prakhar Y Shah, Owen D McArthur, Brandon H Dickson, Michael G Surette, Youngchang Kim, John C Whitney
Journal: MBio
PubMed ID: 36036513
Doi: 10.1128/mbio.02137-22
Products & Services: Polyclonal Antibody Services   
USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation
Authors: Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A J Smits
Journal: Cells
PubMed ID: 36010569
Doi: 10.3390/cells11162492
Products & Services: Proteins, Expression, Isolation and Analysis   
Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
Authors: Zhipeng Ai, Xinyu Xiang, Yangquan Xiang, Iwona Szczerbinska, Yuli Qian, Xiao Xu, Chenyang Ma, Yaqi Su, Bing Gao, Hao Shen, Muhammad Nadzim Bin Ramli, Di Chen, Yue Liu, Jia-Jie Hao, Huck Hui Ng, Dan Zhang, Yun-Shen Chan, Wanlu Liu, Hongqing Liang
Journal: Cell Rep
PubMed ID: 36001968
Doi: 10.1016/j.celrep.2022.111240
Products & Services: Catalog Antibody   
Case report: A novel loss-of-function pathogenic variant in the KCNA1 cytoplasmic N-terminus causing carbamazepine-responsive type 1 episodic ataxia
Authors: Rían W Manville, Richard Sidlow, Geoffrey W Abbott
Journal: Front Neurol
PubMed ID: 36016548
Doi: 10.3389/fneur.2022.975849
Products & Services: Custom Vector Construction   
LIMP2 gene, evolutionarily conserved regulation by TFE3, relieves lysosomal stress induced by cholesterol
Authors: Hanze Guo, Yingying Zhu, Jiarui Li, Qipeng Zhang, Yan Chi
Journal: Life Sci
PubMed ID: 35987341
Doi: 10.1016/j.lfs.2022.120888
Products & Services: Custom Vector Construction   
Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase
Authors: Samantha N Muellers, Mattias M Nyitray, Nicholas Reynarowych, Edina Saljanin, Annie Laurie Benzie, Alan R Schoenfeld, Brian J Stockman, Karen N Allen
Journal: Biochemistry
PubMed ID: 35994320
Doi: 10.1021/acs.biochem.2c00361
Products & Services: Recombinant Proteins   
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses
Authors: Jeroen M J Tas, Ja-Hyun Koo, Ying-Cing Lin, Zhenfei Xie, Jon M Steichen, Abigail M Jackson, Blake M Hauser, Xuesong Wang, Christopher A Cottrell, Jonathan L Torres, John E Warner, Kathrin H Kirsch, Stephanie R Weldon, Bettina Groschel, Bartek Nogal, Gabriel Ozorowski, Sandhya Bangaru, Nicole Phelps, Yumiko Adachi, Saman Eskandarzadeh, Michael Kubitz, Dennis R Burton, Daniel Lingwood, Aaron G Schmidt, Usha Nair, Andrew B Ward, William R Schief, Facundo D Batista
Journal: Immunity
PubMed ID: 35987201
Doi: 10.1016/j.immuni.2022.07.020
Products & Services: Catalog Antibody   

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