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Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine

Authors: Peter J. Halfmann; Kathryn Loeffler; Augustine Duffy; Makoto Kuroda; Jie E. Yang; Elizabeth R. Wright; Yoshihiro Kawaoka; Ravi S. Kane

Journal: Nature Communications

PubMed ID: 38346966

Doi: 10.1038/s41467-024-45495-6

Products & Services: PCR Cloning and Subcloning

Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis

Authors: Marianna de Carvalho Clímaco, Luiza Almeida de Figueiredo, Rayane Cristina Lucas, Guilherme Rafael Gomide Pinheiro, Luísa Mourão Dias Magalhães, Ana Laura Grossi de Oliveira, Raquel Martins Almeida, Fernando Sérgio Barbosa, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Tiago Antonio Mendes, Bin Zhan, Kathryn Marie Jones, Peter Hotez, Maria Elena Bottazzi, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara

Journal: Vaccine

PubMed ID: 37479612

Doi: 10.1016/j.vaccine.2023.07.020

Products & Services: Gene Synthesis

Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis

Authors: Jie Chen, Rui Zhang, Feng Li, Shengli Lin, Jian Wang

Journal: Dig Liver Dis

PubMed ID: 37495427

Doi: 10.1016/j.dld.2023.07.010

Products & Services: Molecular Biology Reagents

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Authors: Prakash Jadhav; Bo Huang; Jerzy Osipiuk; Xiaoming Zhang; Haozhou Tan; Christine Tesar; Michael Endres; Robert Jedrzejczak; Bin Tan; Xufang Deng; Andrzej Joachimiak; Jianfeng Cai; Jun Wang

Journal: European Journal of Medicinal Chemistry

PubMed ID: 38065031

Doi: 10.1016/j.ejmech.2023.116011

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Authors: Prakash Jadhav; Bo Huang; Jerzy Osipiuk; Xiaoming Zhang; Haozhou Tan; Christine Tesar; Michael Endres; Robert Jedrzejczak; Bin Tan; Xufang Deng; Andrzej Joachimiak; Jianfeng Cai; Jun Wang

Journal: European Journal of Medicinal Chemistry

PubMed ID: 38065031

Doi: 10.1016/j.ejmech.2023.116011

Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery

Authors: Natalie S Wallace, John E Gadbery, Cameron I Cohen, Amy K Kendall, Lauren P Jackson

Journal: biorxiv

PubMed ID: 37502979

Doi: 10.1101/2023.07.18.549521

Products & Services: Protein and Antibody Isolation

Non-canonical function of folate/folate receptor 1 during neural tube formation

Authors: Olga A Balashova, Alexios A Panoutsopoulos, Olesya Visina, Jacob Selhub, Paul S Knoepfler, Laura N Borodinsky

Journal: biorxiv

PubMed ID: 37503108

Doi: 10.1101/2023.07.19.549718

Products & Services: Catalog Peptides

Novel Frizzled-specific antibody-based Wnt mimetics and Wnt superagonists selectively activate WNT/β-catenin signaling in target tissues

Authors: Yorick Post, Archana Dilip, Liqin Xie, Asmiti Sura, Nicholas Suen, Jay Ye, Devin Mutha, Angela T Liu, Huy Nguyen, Elizabeth Whisler, Darshini Shah, Shalaka Deshmukh, Navrose Dhaliwal, Ben Bauer, Eskedar Nigatu, Anh Diep, Tom Lopez, Tristan W Fowler, Sung-Jin Lee, Chenggang Lu, Wen-Chen Yeh, Hui Chen, Yang Li

Journal: Cell Chem Biol

PubMed ID: 37413985

Doi: 10.1016/j.chembiol.2023.06.006

Products & Services: Gene Synthesis

Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis

Authors: Yi Zhou, Guofei Cui, Hongwei Xu, Joanne Chun, Doris Yang, Zheng Zhang, Lihui Yang, Jingxiao Wang, Meijuan Wan, Diego F Calvisi, Shumei Lin, Xin Chen, Haichuan Wang

Journal: Cell Death Dis

PubMed ID: 37500626

Doi: 10.1038/s41419-023-05958-y

Products & Services: Catalog Peptides

An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for Preliminary Ex Vivo Analysis

Authors: Aregitu Mekuriaw Arega, Ajit Kumar Dhal, Kali Prasad Pattanaik, Sasmita Nayak, Rajani Kanta Mahapatra

Journal: Appl Biochem Biotechnol

PubMed ID: 37498378

Doi: 10.1007/s12010-023-04658-9

Products & Services: Gene Synthesis