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Crystal Structures of Epstein-Barr Virus Bcl-2 Homolog BHRF1 Bound to Bid and Puma BH3 Motif Peptides

Authors: Chathura D Suraweera, Mark G Hinds, Marc Kvansakul

Journal: Viruses

PubMed ID: 36298777

Doi: 10.3390/v14102222

Products & Services: Bacterial Expression

Greater Phosphorylation of AMPK and Multiple AMPK Substrates in the Skeletal Muscle of 24 Month-old Calorie Restricted Compared to Ad Libitum Fed Male Rats

Authors: Amy Zheng, Seong Eun Kwak, Jesper B Birk, Edward B Arias, Dominic Thorley, Jørgen F P Wojtaszewski, Gregory D Cartee

Journal: J Gerontol A Biol Sci Med Sci

PubMed ID: 36269629

Doi: 10.1093/gerona/glac218

Products & Services: Catalog Antibodies

Structural insights into acetylated histone ligand recognition by the BDP1 bromodomain of Plasmodium falciparum

Authors: Ajit Kumar Singh, Margaret Phillips, Saleh Alkrimi, Marco Tonelli, Samuel P Boyson, Kiera L Malone, Jay C Nix, Karen C Glass

Journal: Int J Biol Macromol

PubMed ID: 36328269

Doi: 10.1016/j.ijbiomac.2022.10.247

Products & Services: Custom Vector Construction

Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry

Authors: Tom Dixon, Derek MacPherson, Barmak Mostofian, Taras Dauzhenka, Samuel Lotz, Dwight McGee, Sharon Shechter, Utsab R Shrestha, Rafal Wiewiora, Zachary A McDargh, Fen Pei, Rajat Pal, João V Ribeiro, Tanner Wilkerson, Vipin Sachdeva, Ning Gao, Shourya Jain, Samuel Sparks, Yunxing Li, Alexander Vinitsky, Xin Zhang, Asghar M Razavi, István Kolossváry, Jason Imbriglio, Artem Evdokimov, Louise Bergeron, Wenchang Zhou, Jagat Adhikari, Benjamin Ruprecht, Alex Dickson, Huafeng Xu, Woody Sherman, Jesus A Izaguirre

Journal: Nat Commun

PubMed ID: 36202813

Doi: 10.1038/s41467-022-33575-4

Products & Services: Gene Synthesis

G3BP/Rin-Binding Motifs Inserted into Flexible Regions of nsP2 Support RNA Replication of Chikungunya Virus

Authors: Sainan Wang, Andres Merits

Journal: J Virol

PubMed ID: 36226983

Doi: 10.1128/jvi.01278-22

Products & Services: Plasmid DNA Preparation Gene Synthesis

Mediator subunit MED1 differentially modulates mutant thyroid hormone receptor intracellular dynamics in Resistance to Thyroid Hormone syndrome

Authors: Moyao Wang, Vincent R Roggero, Lizabeth A Allison

Journal: Mol Cell Endocrinol

PubMed ID: 36191835

Doi: 10.1016/j.mce.2022.111781

Products & Services: Protein and Antibody Isolation

A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity

Authors: Lian-Sheng Cheng, Yong-Feng Cheng, Wen-Ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang, Guodong Shen

Journal: J Transl Med

PubMed ID: 36076251

Doi: 10.1186/s12967-022-03619-w

Products & Services: Mammalian Expression

Nuclear Factor Kappa B Promotes Ferritin Heavy Chain Expression in in Response to Nucleopolyhedrovirus Infection

Authors: Linbao Zhu, Yingxue Liu, Ancheng Wang, Xiya Chen, Handan Zhu, Zhihao Huang, Huihua Cao, Shihuo Liu, Jiaping Xu

Journal: Int J Mol Sci

PubMed ID: 36142290

Doi: 10.3390/ijms231810380

Products & Services: Recombinant Antibody Expression

Tumor-Intrinsic PD-L1 Exerts an Oncogenic Function through the Activation of the Wnt/β-Catenin Pathway in Human Non-Small Cell Lung Cancer

Authors: Yunxia Ma, Rumyana Marinkova, Miljana Nenkov, Lai Jin, Otmar Huber, Jürgen Sonnemann, Natália Peca, Nikolaus Gaßler, Yuan Chen

Journal: Int J Mol Sci

PubMed ID: 36232331

Doi: 10.3390/ijms231911031

Products & Services: Mammalian Expression

A review post-vaccination SARS-CoV-2 serological test: Method and antibody titer response

Authors: Melania Janisha Devi, Shabarni Gaffar, Yeni Wahyuni Hartati

Journal: Anal Biochem

PubMed ID: 36122603

Doi: 10.1016/j.ab.2022.114902

Products & Services: Recombinant Proteins