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Structural basis of fast N-type inactivation in Kv channels

Authors: Xiao-Feng Tan, Ana I Fernández-Mariño, Yan Li, Tsg-Hui Chang, Kenton J Swartz

Journal: Nature

PubMed ID: 40770100

Doi: 10.1038/s41586-025-09339-7

Products & Services: Peptide Synthesis

Lipid interactions and gating hysteresis suggest a physiological role for mechanosensitive channel YnaI

Authors: Nathan Will, Giorgos Hiotis, Yoshitaka Nakayama, Gabriella Angiulli, Zijing Zhou, Charles D Cox, Boris Martinac, Thomas Walz

Journal: Nature Communications

PubMed ID: 40796571

Doi: 10.1038/s41467-025-62805-8.

Products & Services: PCR Cloning and Subcloning

High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants

Authors: Mihkel Örd, Matthew J Winters, Mythili S Subbanna, Natàlia de Martín Garrido, Victoria I Cushing, Johanna Kliche, Caroline Benz, Ylva Ivarsson, Basil J Greber, Peter M Pryciak, Norman E Davey

Journal: Nature Communications

PubMed ID: 40817109

Doi: 10.1038/s41467-025-62765-z.

Products & Services: Peptide Synthesis

POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?

Authors: Hang Liu, Xinyue Li, Mengyi Li, Ziyang Sun, Xu Wang, Juehong Li, Binbin Xu, Qian Chen, Cunyi Fan, Hongjiang Ruan

Journal: Advanced Science

PubMed ID: 40823759

Doi: 10.1002/advs.202507951

Products & Services: Custom Vector Construction

HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates

Authors: Krystal M Ma, Henry J Sutton, Payal P Pratap, Jon M Steichen, Diane Carnathan, James Quinn, Oleksandr Kalyuzhniy, Alessia Liguori, Sashank Agrawal, Sabyasachi Baboo, Patrick Madden, Christopher A Cottrell, Jordan R Willis, Jeong-Hyun Lee, Elise Landais, Xiaozhen Hu, Parham Ramezani-Rad, Gabriel Ozorowski, Vanessa R Lewis, Jolene K Diedrich, Xiaoya Zhou, Tasha K Altheide, Nicole Phelps, Erik Georgeson, Nushin B Alavi, Danny Lu, Saman Eskandarzadeh, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullen, Murillo Silva, Mariane B Melo, Sunny Himansu, Darrell J Irvine, Dennis R Burton, John R Yates 3rd, James C Paulson, Devin Sok, Ian A Wilson, Guido Silvestri, Andrew B Ward, Shane

Journal: Science immunology

PubMed ID: 40845127

Doi: 10.1126/sciimmunol.adt6660

Products & Services: Recombinant Antibody Expression

Discovery of CRISPR-Cas12a clades using a large language model

Authors: Yuanyuan Feng, Junchao Shi, Zhanwei Li, Yongqian Li, Jiaxi Yang, Shisheng Huang, Jinfang Zheng, Wei Han, Yunbo Qiao, Jun Zhang, Qi Liu, Yao Yang, Chunyi Hu, Lina Wu, Xiaokang Zhang, Jin Tang, Xingxu Huang, Peixiang Ma

Journal: Nature Communications

PubMed ID: 40849498

Doi: 10.1038/s41467-025-63160-4.

Products & Services: Synthetic Guide RNA

DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides

Authors: Qian Ren, Jing Wang, Vinay Idikuda, Shanwen Zhang, Jeehae Shin, W Grant Ludlam, Luis M Real Hernandez, Sara Zdancewicz, Alex J B Kreutzberger, Hucheng Chang, Volker Kiessling, Lukas K Tamm, Ahmad Jomaa, Ilya Levental, Kirill Martemyanov, Baron Chanda, Huan Bao, Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr

Journal: Nature Communications

PubMed ID: 40858559

Doi: 10.1038/s41467-025-63275-8.

Products & Services: Protein and Antibody Isolation

FlaB-expressing bacterial uter membrane vesicles vaccine mediating anti-tumor immune response via promoting DCs activation and lymph nodes-homing

Authors: Kaiwei Wang, Chang Xu, Minming Chen, Yifan Yan, Nanhui Liu, Changhao Zhao, Bo Liu, Yanbin Liu, Jianjiang Chen, Xiaoliang Ding, Yicong Bian, Lin Song, Xuyu Bian, Yumin Wu, Liyan Miao, Zhuang Liu

Journal: Nano Research

PubMed ID: 40817136

Doi: 10.26599/NR.2025.94907612

Products & Services: ELISA Kits

In situ proximity labeling of proteins associated with circRNA and RNA G-quadruplexes

Authors: Jing Mo, Zonggui Chen, Manman Cui, Xin Fang, Ruihan Li, Shanshan Qin, Zhenlin Zhou, Mei Sun, Jinjun Wu, Chuan He, Fang Wang, Haojian Zhang, Xiang Zhou, Xiaocheng Weng

Journal: Nature Chemical Biology

PubMed ID: 40775047

Doi: 10.1038/s41589-025-01993-2

Products & Services: Protein Electrophoresis and Western

Aligned Electrospun Fibers Inducing Cell and Nuclear Morphology Remodeling via Ras-Associated Protein 1/Yes-Associated Protein Signaling Enhances Bone Regeneration

Authors: Shengjie Jiang, Jialiang Zhou, Cancan Zhao, Liyun Wang, Zeyu Fu, Mazaher Gholipourmalekabadi, Xudong Wang, Changyong Yuan, Kaili Lin

Journal: Advanced Fiber Materials

Doi: 10.1007/s42765-025-00596-9

Products & Services: Catalog Antibodies